Q9KPV0

PR
Gene name
glnD
Protein name
Bifunctional uridylyltransferase/uridylyl-removing enzyme
Names
UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein
Species
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
KEGG Pathway
vch:VC_2262
EC number
2.7.7.59: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-58 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9KPV0

Entry ID Method Resolution Chain Position Source
AF-Q9KPV0-F1 Predicted AlphaFoldDB

No variants for Q9KPV0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9KPV0

No associated diseases with Q9KPV0

6 regional properties for Q9KPV0

Type Name Position InterPro Accession
domain ACT domain 693 - 777 IPR002912-1
domain ACT domain 800 - 876 IPR002912-2
domain Polymerase, nucleotidyl transferase domain 57 - 108 IPR002934
domain HD/PDEase domain 447 - 600 IPR003607
domain HD domain 451 - 584 IPR006674
domain PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase 176 - 314 IPR013546

Functions

Description
EC Number 2.7.7.59 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
[protein-PII] uridylyltransferase activity Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).
phosphoric diester hydrolase activity Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.

2 GO annotations of biological process

Name Definition
nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
regulation of nitrogen utilization Any process that modulates the frequency, rate or extent of nitrogen utilization.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPYQSPITFQ EPQLTVESLK QQLESFTEYQ KQEFFDHHPV TDLVLGRSEY MDLLLHRLWQ
70 80 90 100 110 120
FFGFDELVEV SLVAVGGYGR GELHPLSDID LLVLSQQPLS EQVANKISQF LTLLWDLKLE
130 140 150 160 170 180
IGHAVRTVEQ CAEIGKADLT VATNLQEARL LCGCEETFHR LKMVIHSESF WPSEIFYQAK
190 200 210 220 230 240
VREQKERHAR YHDTTYNLEP DIKSTPGGLR DIHTLSWVAR RHFGATSLYE MSRFGFLTDA
250 260 270 280 290 300
EYRELVECQD FLWRVRFALH IELKRYDNRL TFAHQVQVAR HLGYFGEGNR GIEMMMKEFF
310 320 330 340 350 360
RTLRRVAELN KMLLKIFDKA ILNNGEEAEA VIIDDDFQRR GNMIEARKPA LFQARPETIL
370 380 390 400 410 420
DMFLHMASDS TIESVAPATM RQLRTARRRL NKFLHTLPAA REKFIELVRH PNALHKAFSQ
430 440 450 460 470 480
MHKLGVLAAY LPQWNQIVGQ MQFDLFHVYT VDEHSIRLLK HIHLFSDANN HDRHPICCEI
490 500 510 520 530 540
YPKIQKKELL ILAAIFHDIG KGRGGDHSEI GADEAFDFCI EHGLSKPEAK LVAWLVKNHL
550 560 570 580 590 600
LMSVTAQRRD IYDPDVIIEF AKKVRDEERL EYLVCLTVAD ICATNPELWN SWKRTLLAEL
610 620 630 640 650 660
FYSTQRALRR GLENPVDVRE RIRHNQQMAS ALLRKEGFSS REIEVLWQRF KADYFLRHTH
670 680 690 700 710 720
KQIAWHCTHL LRHEDSSKPL VLLSKKATRG GTEVFIYTKD QAALFATVVA ELDRRNLNVH
730 740 750 760 770 780
DAQIMASKDG YVLDTFMVLD QNGQAIEEDR HQALIRHLVH VLEDGRPTTQ KARRIPRNLQ
790 800 810 820 830 840
HFKVKTQVDF LPTKSKKRTL MEFVALDTPG LLATVGATFA ELNLDLHAAK ITTIGERAED
850 860 870
LFILTNAQGT RLNEEEEQHL REKLIEHVAE LAPSAQ