Q9KNI7

PR
Gene name
add
Protein name
Adenosine deaminase
Names
Adenosine aminohydrolase
Species
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
KEGG Pathway
vch:VC_2751
EC number
3.5.4.4: In cyclic amidines
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

263-334 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for Q9KNI7

Entry ID Method Resolution Chain Position Source
6N91 X-ray 205 A A/B 1-334 PDB
AF-Q9KNI7-F1 Predicted AlphaFoldDB

No variants for Q9KNI7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9KNI7

No associated diseases with Q9KNI7

1 regional properties for Q9KNI7

Type Name Position InterPro Accession
domain Adenosine deaminase domain 7 - 329 IPR001365

Functions

Description
EC Number 3.5.4.4 In cyclic amidines
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
2'-deoxyadenosine deaminase activity Catalysis of the reaction: 2'-deoxyadenosine + H2O = deoxyinosine + NH3.
adenosine deaminase activity Catalysis of the reaction: adenosine + H2O = inosine + NH3.
zinc ion binding Binding to a zinc ion (Zn).

5 GO annotations of biological process

Name Definition
adenosine catabolic process The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.
hypoxanthine salvage Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo synthesis.
inosine biosynthetic process The chemical reactions and pathways resulting in the formation of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.
nucleotide metabolic process The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
purine ribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MITSSLPLTD LHRHLDGNIR TQTILELGQK FGVKLPANTL QTLTPYVQIV EAEPSLVAFL
70 80 90 100 110 120
SKLDWGVAVL GDLDACRRVA YENVEDALNA RIDYAELRFS PYYMAMKHSL PVTGVVEAVV
130 140 150 160 170 180
DGVRAGVRDF GIQANLIGIM SRTFGTDACQ QELDAILSQK NHIVAVDLAG DELGQPGDRF
190 200 210 220 230 240
IQHFKQVRDA GLHVTVHAGE AAGPESMWQA IRDLGATRIG HGVKAIHDPK LMDYLAQHRI
250 260 270 280 290 300
GIESCLTSNL QTSTVDSLAT HPLKRFLEHG ILACINTDDP AVEGIELPYE YEVAAPQAGL
310 320 330
SQEQIRQAQL NGLELAFLSD SEKKALLAKA ALRG