Q9KKS5

PR
Gene name
nagB
Protein name
Glucosamine-6-phosphate deaminase
Names
GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase
Species
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
KEGG Pathway
vch:VC_A1025
EC number
3.5.99.6: In other compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

120-191 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for Q9KKS5

Entry ID Method Resolution Chain Position Source
4R7T X-ray 210 A A/B/C 1-266 PDB
5HJ5 X-ray 170 A A/B/C/D 1-266 PDB
AF-Q9KKS5-F1 Predicted AlphaFoldDB

No variants for Q9KKS5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9KKS5

No associated diseases with Q9KKS5

7 regional properties for Q9KKS5

Type Name Position InterPro Accession
conserved_site Twin-arginine translocation pathway, signal sequence 1 - 31 IPR006311
domain Molybdopterin oxidoreductase 96 - 567 IPR006656
domain Molybdopterin dinucleotide-binding domain 714 - 822 IPR006657
domain Molybdopterin oxidoreductase, 4Fe-4S domain 39 - 95 IPR006963
conserved_site Twin-arginine translocation pathway, signal sequence, bacterial/archaeal 3 - 31 IPR019546
binding_site Molybdopterin oxidoreductase, molybdopterin cofactor binding site 44 - 61 IPR027467
domain Nitrate reductase NapA-like, molybdopterin-binding domain 710 - 828 IPR041957

Functions

Description
EC Number 3.5.99.6 In other compounds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
glucosamine-6-phosphate deaminase activity Catalysis of the reaction: D-glucosamine 6-phosphate + H(2)O = beta-D-fructose 6-phosphate + NH(4)(+).
identical protein binding Binding to an identical protein or proteins.

4 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
glucosamine catabolic process The chemical reactions and pathways resulting in the breakdown of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.
N-acetylglucosamine catabolic process The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.
N-acetylneuraminate catabolic process The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRLIPLKAAA QVGKWAAAHI VKRINEFQPT AERPFVLGLP TGGTPLATYK ALIEMHKAGE
70 80 90 100 110 120
VSFKHVVTFN MDEYVGLAAD HPESYRSFMY NNFFNHIDIQ EENINLLNGN TDDHEAECKR
130 140 150 160 170 180
YEDKIKSYGK INLFMGGVGN DGHIAFNEPA SSLSSRTRIK TLTEDTRIAN SRFFDGDINQ
190 200 210 220 230 240
VPKYALTIGV GTLLDAQEIM ILVTGHNKAL ALQAAVEGSV NHLWTVSALQ LHPKAVIVCD
250 260
EPSTQELKVK TVKYFTELEA KNIVGF