Q9KI19

PR
Gene name
rpoS
Protein name
RNA polymerase sigma factor RpoS
Names
Sigma S, Sigma-38
Species
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
KEGG Pathway
cbu:CBU_1669
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-109 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9KI19

Entry ID Method Resolution Chain Position Source
AF-Q9KI19-F1 Predicted AlphaFoldDB

No variants for Q9KI19

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9KI19

No associated diseases with Q9KI19

10 regional properties for Q9KI19

Type Name Position InterPro Accession
domain RNA polymerase sigma-70 141 - 154 IPR000943-1
domain RNA polymerase sigma-70 165 - 173 IPR000943-2
domain RNA polymerase sigma-70 289 - 301 IPR000943-3
domain RNA polymerase sigma-70 310 - 325 IPR000943-4
domain RNA polymerase sigma-70 325 - 336 IPR000943-5
domain RNA polymerase sigma-70 region 3 197 - 271 IPR007624
domain RNA polymerase sigma-70 region 2 117 - 186 IPR007627
domain RNA polymerase sigma-70 region 4 285 - 338 IPR007630
domain RNA polymerase sigma-70 region 1.2 79 - 110 IPR009042
domain RNA polymerase sigma-70 like domain 113 - 339 IPR014284

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
sigma factor activity Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.

1 GO annotations of biological process

Name Definition
DNA-templated transcription initiation The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKTKTTKKTI KKAAKKIKKP SKRKIKKTAK KSRPKKPIKA SDHGLIFAKT KKETTEKEDA
70 80 90 100 110 120
ELANAKAKTK KRRETRSSDP TQIYLRELGF QPLLNAKEEL KIARRVHKGD PKARKQMIEA
130 140 150 160 170 180
NLRLVVKIAR HYVNRGLPFL DLIEEGNLGL LTAVEKFDPE RGFRFSTYAT WWIRQTIERA
190 200 210 220 230 240
IMNQSRTVRL PIHVIKELNV YLRTAKKLTQ EVDHEATPED VAHLIDKPVQ EIRRIMDLAP
250 260 270 280 290 300
SATSIDVPIS EDGQKSLVDT LADDNNIDPA RLIQNVDLQD HIERWLAQLD ERHREVVILR
310 320 330 340 350
FGLHENEKGT LEAVGKAVGL TRERVRQIQI DALQQLRHIL EMEGVTGEEV ED