Q9KA77

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans)
KEGG Pathway
bha:BH2413
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

9-171 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9KA77

Entry ID Method Resolution Chain Position Source
AF-Q9KA77-F1 Predicted AlphaFoldDB

No variants for Q9KA77

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9KA77

No associated diseases with Q9KA77

6 regional properties for Q9KA77

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 231 - 400 IPR000795
domain Small GTP-binding protein domain 233 - 390 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 46 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 157 - 205 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 505 - 621 IPR023115
domain Translation initiation factor IF-2, domain II 406 - 500 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRKMRIYEYA KEKNLSSKEV IEKLKGLNVH VSNHMSVIDE KTITLLEGNG NQKQGGSGKP
70 80 90 100 110 120
EQQKKAGEKK PAQDHGQRKP NTAPAKANNQ HDRSQGSDQQ KGKAQDGGQK PKHKGNKNKK
130 140 150 160 170 180
QHQKNNNNKR NQRGRGRQPE MNKAKPLPEK VTFSGSLTVG ELAEKLNKEP SELIKKLMFL
190 200 210 220 230 240
GVMATINQEL DKDSIELICE DYGVEVEEEV IIDETDIESY VVEDDPSLLK ERPPVVTIMG
250 260 270 280 290 300
HVDHGKTTLL DSIRNTKVTE GEAGGITQHI GAYQVTVEGK KITFLDTPGH AAFTTMRARG
310 320 330 340 350 360
AQVTDITILV VAADDGVMPQ TKEAISHAKA AGVPIIVAVN KMDKETANPD RVMQELTEYE
370 380 390 400 410 420
LVPEAWGGET IFVNVSALTG TGIDELLEMV LLVAEVEELK ANPDRLARGT VIEAELDKGR
430 440 450 460 470 480
GPVATLLVQS GTLKVGDPIV VGSTFGRVRA MVNDEGRRVK AVGPSTPVEI TGLNDVPQAG
490 500 510 520 530 540
DQFQAFADEK KARSIGEARA TRQKEEERAE TSKVSLDDLF NQIQQGEVKE INVIIKADVQ
550 560 570 580 590 600
GSVEAMRGSL EKIDVEGVKI NIIHTGVGAI TESDIILAAA SNAIVIGFNV RPDGGAKRTA
610 620 630 640 650 660
EQEKVDIRLH RVIYNAIEEI EAAMKGMLDP EYEEKIIGQV EVRTTFKVSR IGTIAGSYVT
670 680 690 700 710 720
EGKIVRDATV RLIRDGVVIY EGSINALKRF KDDVKEVAQG YECGITLENF NDIKEGDIIE
AYVMEEIERT