Q9K6W8

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans)
KEGG Pathway
bha:BH3606
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

757-838 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9K6W8

Entry ID Method Resolution Chain Position Source
AF-Q9K6W8-F1 Predicted AlphaFoldDB

No variants for Q9K6W8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9K6W8

No associated diseases with Q9K6W8

9 regional properties for Q9K6W8

Type Name Position InterPro Accession
domain Helicase, C-terminal 415 - 570 IPR001650
conserved_site SEC-C motif 820 - 837 IPR004027
domain SecA DEAD-like, N-terminal 5 - 383 IPR011115
domain SecA Wing/Scaffold 569 - 779 IPR011116
domain SecA, preprotein cross-linking domain 227 - 339 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 88 - 246 IPR014001
domain SecA motor DEAD 2 - 571 IPR014018
conserved_site SecA conserved site 481 - 496 IPR020937
domain SecA, C-terminal helicase domain 401 - 541 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLGLLKKVVG DPSQRQLKKN QKIADQVEAL SDEMKSLSDD GLRQKTEEFK KRYKNGESLD
70 80 90 100 110 120
DLLPEAYAVV REAATRVLNM TPYPVQILGA IALHQGNIAE MKTGEGKTLV GTMPVYLNAL
130 140 150 160 170 180
AGKGVHVVTV NDYLARRDSE QMGAMFEFLG LTVGLNVPGL SKEEKKEAYQ ADITYGTNNE
190 200 210 220 230 240
FGFDYLRDNM VLYKEQMVQR SLNFALVDEV DSILIDEART PLIISGSVER STKLYSQANS
250 260 270 280 290 300
FVRVLKNEED YTLDEKTKSV QLTEEGVNKA ERAFNIDNLF DQRHVQLLHH INQAMKAHVV
310 320 330 340 350 360
MHRDADYVVE NGEIVIVDQF TGRLMKGRRY SDGLHQAIEA KEGLQIQRES MTLASITFQN
370 380 390 400 410 420
YFRMYQKLAG MTGTAKTEEE EFRNIYGMDV MVIPTNKPVI RDDRPDLIFK TMDAKFKAVV
430 440 450 460 470 480
NEIEELYKKG QPVLVGTVSV ETSELVSTLL KKRRIPHHVL NAKNHEKEAE IIENAGHRGA
490 500 510 520 530 540
VTIATNMAGR GTDIKLGEGV RELGGLHVLG TERHESRRID NQLRGRSGRQ GDPGSSQFYL
550 560 570 580 590 600
SMEDELMRRF GSDNMRAMMD KLGMEEDQPI ESKLVSRAVE TAQKRVEGNN FDARKQILQY
610 620 630 640 650 660
DDVMREQREI IYKQRMEVLE SDNLREIVEK MILSVIERNV QLHTPESEVP EDWDYGAIVN
670 680 690 700 710 720
FMKANLLNED DLTEKDIWGK DPEEIVEIIY DKVIERYNKK EEEFTPEHMR EFEKVIMLRT
730 740 750 760 770 780
VDRKWMNHID QMDQLRQGIH LRAYGQNDPL REYRFEGFEM FEAMVASIEE EVAMYVMKAQ
790 800 810 820 830
VQQNLQREKV AEGQAVQPKP TDGDSKAKRQ PVRKKETVGR NEPCPCGSGK KYKNCCGQ