Q9JZ24
Gene name |
trmB |
Protein name |
tRNA (guanine-N(7)-)-methyltransferase |
Names |
tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase |
Species |
Neisseria meningitidis serogroup B (strain MC58) |
KEGG Pathway |
nme:NMB1328 |
EC number |
2.1.1.33: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9JZ24
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9JZ24-F1 | Predicted | AlphaFoldDB |
No variants for Q9JZ24
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9JZ24 | |||||
No associated diseases with Q9JZ24
No regional properties for Q9JZ24
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9JZ24 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.33 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| tRNA methyltransferase complex | A multimeric protein complex involved in the methylation of specific nucleotides in tRNA. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| tRNA (guanine-N7-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| RNA (guanine-N7)-methylation | The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule. |
| tRNA methylation | The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTDTAENQTQ | NNWQAGHPRS | IRSFVLRQSH | MTAAQQRAID | TLWDSFGIDY | QATPADLDAR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FGSSRPKILE | IGFGMGTATA | EIARRLPETD | FLAIDVHGPG | VGNLLKLIDE | NHLENIRVMR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HDAVEVVENM | LQDGSLDGIH | IFFPDPWHKK | RHHKRRLIQA | PFIAKLLPKL | KTGGYIHLAT |
| 190 | 200 | 210 | 220 | 230 | |
| DWEEYAQQML | EVLSSFDSLQ | NTAADYAPTP | DYRPETKFEA | RGKRLGHGVW | DLVFKRIG |