Q9JMB0

PR
Gene name
Gkap1 (Gkap42)
Protein name
G kinase-anchoring protein 1
Names
cGMP-dependent protein kinase-anchoring protein of 42 kDa
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:56278
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-64 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9JMB0

Entry ID Method Resolution Chain Position Source
AF-Q9JMB0-F1 Predicted AlphaFoldDB

14 variants for Q9JMB0

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389260550 52 N>K No EVA
rs3389289756 93 Q>L No EVA
rs3389260528 106 S>* No EVA
rs234698486 117 K>R No EVA
rs250380433 152 E>D No EVA
rs3389244403 174 D>E No EVA
rs3389215347 176 P>H No EVA
rs3389298071 181 L>F No EVA
rs3389283328 182 K>N No EVA
rs3389283382 197 S>L No EVA
rs3389288142 197 S>T No EVA
rs3389283369 199 S>Y No EVA
rs3389288094 225 K>Q No EVA
rs3389280133 236 T>R No EVA

No associated diseases with Q9JMB0

1 regional properties for Q9JMB0

Type Name Position InterPro Accession
domain Pyruvate phosphate dikinase, AMP/ATP-binding 1079 - 1277 IPR002192

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.

1 GO annotations of molecular function

Name Definition
identical protein binding Binding to an identical protein or proteins.

3 GO annotations of biological process

Name Definition
G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase (GC) activity and a subsequent increase in the concentration of cyclic GMP (cGMP).
positive regulation of insulin receptor signaling pathway Any process that increases the frequency, rate or extent of insulin receptor signaling.
signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASAVLSSVL TTASRFALLQ VDSGSGSDSE PGKGKGRSNG KSQTLGNKAT SNEKKREKRR
70 80 90 100 110 120
KKKEQQQSEA NELRNLAFKK IPQKSSHSIC NVQHELSSPN PAQKESREEN WQEWRQKDEQ
130 140 150 160 170 180
LTSEMFEADL EKALLLSKLE YEEHKQDYEN AETASTQTKG INKKDKRKNH QGKDKPVTVS
190 200 210 220 230 240
LKDFQCEDHI SKKAEESNSA QTLSHDGGFF NRLEDDVHKI LIREKRREQL TEHNGTDNSP
250 260 270 280 290 300
APEHNQEVGL KDGRIERLKL ELERKDAEIQ KLKAVITQWE AKYKEVKARN GQLLKMLQEG
310 320 330 340 350 360
EMKDKAEILL QVDESQSIKN ELTVQVSSLH AALEQERSKV KVLQAELAKY QGGRKGKRNF
EPDHCR