Q9JGF2

PR
Gene name
ORF1
Protein name
Non-structural polyprotein 1AB
Names
Species
Avian nephritis virus 1 (ANV-1)
KEGG Pathway
EC number
2.7.7.48: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-60 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q9JGF2

Entry ID Method Resolution Chain Position Source

No variants for Q9JGF2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9JGF2

No associated diseases with Q9JGF2

2 regional properties for Q9JGF2

Type Name Position InterPro Accession
domain RNA-directed RNA polymerase, C-terminal domain 1167 - 1452 IPR001205
domain RNA-directed RNA polymerase, catalytic domain 1257 - 1390 IPR007094

Functions

Description
EC Number 2.7.7.48 Nucleotidyltransferases
Subcellular Localization
  • Host membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
host cell membrane Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
cysteine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.

3 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
viral RNA genome replication The replication of a viral RNA genome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASAGPTGAG ARPPKAFTAQ AGLAKLVNPA GLNSILARGK EKFGGTQAWK ELMGCDVIFA
70 80 90 100 110 120
RSISHWYGIK GTTYYELTVA LGQPLYKPVT DPELTEEEKA VMTAVQSRFA QSNSSVVLTR
130 140 150 160 170 180
TLLNKTCELK DRIRELTDEL GQTEVHLARE KVKAAALKLE NRKLFVENQE LKDQLEKERT
190 200 210 220 230 240
KHGWKGLKTL CLWIFLATLI GGYITGSNAA CTLVDVPSPM KVGYDTFKQM CIHKDSYLPD
250 260 270 280 290 300
GAFDKESLAL ECSKQMDYMD CKEVITDSIS GKTSFAGMLR DVFRVDEIVT AIRTVVRFAM
310 320 330 340 350 360
DFSLAYPICV MFVLILTRNK KHAIISACCA LVAKCCGLRL LPFTLVLTYA PSETAIAGCI
370 380 390 400 410 420
YGLGYISIPL VTFLHWVGLV LKAILVPDDC YIGTRVSHAL AWSIMLPMWI ITQELMAFTE
430 440 450 460 470 480
FPLELQIVTT VVVCTAGFGF RYLTGTVTIT EPDGTVKKYK RIFNAKSAIG TISTVFFEKA
490 500 510 520 530 540
KAIRGVIPSF PSKADNIVKI EVDVDGGSAG VGFRLGNYIY TAGHVVGEAK IAKITWKGLT
550 560 570 580 590 600
SQAKVLGHIE LPLFTDTLAR LEIPKPFQQL PVFRLAKSSE NDYVQMVCFD NQLQNVVTFS
610 620 630 640 650 660
GWANIDGDYL NAPFETYAGT SGSPIINRDG RMLGVHFGSN AVVSQGFVIT RLFATEPAVK
670 680 690 700 710 720
QCKSDEDLAD EIVRKVMGGI RISFASLTSE LEKQRDELNA LKQMVNDLID TDLVALEKKK
730 740 750 760 770 780
GKTKRTVRGQ KHKTKAISKA AFMKTKVLTE EEYRRLEEEG FTKDEIKDIV DNLREQAWLD
790 800 810 820 830 840
YQNQLDEEGD DDWYEQMEED QRINDQIDQN IERDLEDRGE WYGQRKITFK QRAMLRFIQL
850 860 870 880 890 900
GRQQQVATVS FPDGYEDRAE ELYNKVVTTE DLPEGETSEA ALSLPNKIVH QAGKRLNFKH
910 920 930 940 950 960
VKIHPDKTFM KSGVTQIEEK PEGDIILKAK TTTLAPKEEP VIQQVEQQPQ VEQQQQPQQP
970 980 990 1000 1010 1020
VVEEKKRTPP PKPQRKPKTG AKAKCLDCGE TFVERQDFHV CKSKKLNEPP SGGYTPVPDH
1030 1040 1050 1060 1070 1080
LRWNNWQIYM EPLDLRITVP ENYPILGHIA IDKLVERKKK VNDPLLKMLE QPKCEGFTST
1090 1100 1110 1120 1130 1140
TWTRKAYTKS FEKFDYGDAV DFVQDYPELT AFADAAVLAE VGYMEGTHVI PIQETSKNMD
1150 1160 1170 1180 1190 1200
STPAFPKMLD FDSERDYLEA HGMKEYIDTQ LGVQSGKPLW WCFLKNEILK EKKVSEDDIR
1210 1220 1230 1240 1250 1260
IITCSDPVIT RLGASFDSEQ NERMKERTET HHAQVGWTPF FGGLDKRVRR ITSCGRTQVL
1270 1280 1290 1300 1310 1320
ELDWTRFDGT IPVQLFQRMR ELRKFFLTRR SRRRYGKLLD WYNAQLTDRI TLLPTGEVTH
1330 1340 1350 1360 1370 1380
VKKGNPSGQF STTVDNNLVN EWLTAFEFGY QHLENHGIIP TVRDYRANVD FLCYGDDRLL
1390 1400 1410 1420 1430 1440
AFNPSFVNYD PQVTIDMYKN IFGMWVKPEN IKLFDSPTGS SFCGFTLVKP HGQWVGVVNV
1450 1460 1470 1480 1490 1500
NKLLQSLKTP TRRLPDLESL WGKLVSLKIM CYHSDPEAVS YLSNQIRRVE EYARAEGIEL
1510
PEVGPDFYRK IW