Q9J7Z2

PR
Gene name
Protein name
RNA-directed RNA polymerase
Names
RdRp, RNA replicase, Protein A
Species
Pariacoto virus (PaV)
KEGG Pathway
vg:956347
EC number
2.7.7.48: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

844-949 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q9J7Z2

Entry ID Method Resolution Chain Position Source

No variants for Q9J7Z2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9J7Z2

No associated diseases with Q9J7Z2

3 regional properties for Q9J7Z2

Type Name Position InterPro Accession
domain RNA-directed RNA polymerase, C-terminal domain 465 - 696 IPR001205
domain RNA-directed RNA polymerase, catalytic domain 558 - 683 IPR007094
domain Nodavirus methyltransferase domain 91 - 233 IPR043647

Functions

Description
EC Number 2.7.7.48 Nucleotidyltransferases
Subcellular Localization
  • Host mitochondrion outer membrane
  • Part of the 30- to 90-nm invaginations of the host mitochondrial outer membrane that form the viral replication complexes vesicules
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.

2 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.
viral RNA genome replication The replication of a viral RNA genome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEEHIPLPSQ YESPKALPPR VPSSRWLRSL RPRLANSCLA LKIRAHESLV KIRLCKPYDA
70 80 90 100 110 120
QSRSKIIEKV IERRETRKTL AHQLKDLKLV PVARDHTHGR AAKFRTSANI WMNEAMRAAG
130 140 150 160 170 180
YEPYNVSMSN HDIERGNRYF YFAKDLTIPY RNDPVSDNTG FVFCDVDYYA DMEKWMQHFK
190 200 210 220 230 240
PMLLYTLVPE SLSYHCDDHS FHVNDDRVFF DVRGGASYSH QLWDYTGDTI CVRGKNKELL
250 260 270 280 290 300
VFTIEQKCIQ GDPHRRIIFL EPAARVAWPF YKPMKVEVGL KRKCMTAGQV NVLYEPIDDK
310 320 330 340 350 360
ISLSASGSRH TVETTGRTLA AITARMKNKT SPPMVADVER ILRDAGDKEA CVNAPILFEL
370 380 390 400 410 420
IPEAKFRVNV VKTTATPTHF QPLGPLRTED GETCGHAVTT TLATAPALLP MRGVNSDVAT
430 440 450 460 470 480
VNGRVKKPAN TVIPFKEYKE YASEFVEFLV PEPGVGHPWD TAAVREVQDN RQQKARINMV
490 500 510 520 530 540
AATVSTHSSN RLKAFIKAEA YAATNDPRNI TTMAPELTLM MSCFTYAFKE KILYEQPWYG
550 560 570 580 590 600
PGKTPKQVGR RLQSIAKHGT LESDYSRFDG SISEWLQKNV VKAAYMRFFK EHQRTEFQSW
610 620 630 640 650 660
FSKVFMQMGT TTAGVRYEAG WGTRSGSPIT TDGNTMLNAF VVYCCYRKLC HTPAEAWRKL
670 680 690 700 710 720
SQGALLTGDD AVLAHENGLE PALLDVVKNL GLKVEAKVNG PDDPVSFCGR IYPRLSDCIT
730 740 750 760 770 780
SFQDPLRTIP KLHLTTNKGV SPEQAAANRA HGYLATDKAT PIIGTWARRV IELTGDLKVK
790 800 810 820 830 840
GATREEQYKL SNAHQQLDPS LIETAMANIL GIDVGELKAL DKAVSEAKAL DQMPVVLGNC
850 860 870 880 890 900
YKHKIEAVVG GEVVGPGPRV ETVEPNHEQS SGTPEVVPEM AGHSERRDKS SNPRPGGKAE
910 920 930 940 950 960
GLSSKAGKPR VPTRPAADRK AAAGSGNRRG PTNGRRPIRD RAPRGGGRPN PGTTPPVSNS
970
ETTTTTAVVH ASA