Q9I472

PR
Gene name
cobO (PA1272)
Protein name
Corrinoid adenosyltransferase
Names
Cob(II)alamin adenosyltransferase, Cob(II)yrinic acid a,c-diamide adenosyltransferase, Cobinamide/cobalamin adenosyltransferase
Species
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG Pathway
pae:PA1272
EC number
2.5.1.17: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-59 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9I472

Entry ID Method Resolution Chain Position Source
AF-Q9I472-F1 Predicted AlphaFoldDB

No variants for Q9I472

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9I472

No associated diseases with Q9I472

1 regional properties for Q9I472

Type Name Position InterPro Accession
domain Cob(I)alamin adenosyltransferase N-terminal domain 1 - 26 IPR025826

Functions

Description
EC Number 2.5.1.17 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
cob(I)yrinic acid a,c-diamide adenosyltransferase activity Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin.

2 GO annotations of biological process

Name Definition
cobalamin biosynthetic process The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
porphyrin-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNESPEKDQR HRERMERKKA VVDEKIAQAR DERGVLLVHS GNGKGKSSSA FGMVARALGH
70 80 90 100 110 120
GMKVGVVQFI KGAASTGEEA FFRRFPEEVS YHVMGEGFTW ETQDRQRDIA KAEAAWKVAA
130 140 150 160 170 180
QLLADPDVGL VVLDELNIAL KHGYLELDRV LADIQARPAM QHVVVTGRGA QPGMIEAADT
190 200
VTEMSLVKHA FKAGIKAQKG VEF