Q9I165

PR
Gene name
treA
Protein name
Periplasmic trehalase
Names
Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase
Species
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG Pathway
pae:PA2416
EC number
3.2.1.28: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-71 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9I165

Entry ID Method Resolution Chain Position Source
AF-Q9I165-F1 Predicted AlphaFoldDB

No variants for Q9I165

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9I165

No associated diseases with Q9I165

2 regional properties for Q9I165

Type Name Position InterPro Accession
conserved_site Glycoside hydrolase, family 37, conserved site 157 - 170 IPR018232-1
conserved_site Glycoside hydrolase, family 37, conserved site 453 - 462 IPR018232-2

Functions

Description
EC Number 3.2.1.28 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
  • Periplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
periplasmic space The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).

2 GO annotations of molecular function

Name Definition
alpha,alpha-trehalase activity Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose.
trehalase activity Catalysis of the hydrolysis of trehalose or a trehalose derivative.

3 GO annotations of biological process

Name Definition
cellular catabolic process The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
cellular hyperosmotic response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
trehalose catabolic process The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPDRTALPRA MLAAWVLLLL AACSQGPAPT PPASWGWQDA SGERAIAPDE AYPELFQAVQ
70 80 90 100 110 120
ENRLFSDQKH FVDALPLREP ARIRADYLRE RERPGFDLRA FVGRNFEESG SVETAPPEAG
130 140 150 160 170 180
ADLASHISDL WPALTRHYEQ VPAHSSLLPL PKPYVVPGGR FREVYYWDSY FTMLGLAESG
190 200 210 220 230 240
QHQRVRDMLD NFAYLIDTYG HIPNGNRSYY LSRSQPPFFA YMVDLQARRE GDAAYRRYLP
250 260 270 280 290 300
QLQKEYAYWM EGSAGLRPNE ARLHVVKLAD GSLLNRYWDN RDTPRQESFL EDRATAARAP
310 320 330 340 350 360
QRPAGEVYRD LRAGAESGWD FSSRWLDDGR ELASIRTTAI VPVDLNALLY HLERIIAKAC
370 380 390 400 410 420
ASSALKACEQ GYGARAEKRR QAIEDHLWHP AGYYADYDWQ RRRPIERINA ASLFPLFTGL
430 440 450 460 470 480
ASAERAGRTA DSVAAQLLRP GGLATTTRAS GQQWDEPNGW APLQWVAVQG LRAYGRDALA
490 500 510 520 530 540
EDIGRRFLAQ VQQVYDREGK LVEKYDISGN QGGGGGGEYP LQDGFGWSNG VTLQLLRLYG
PGAGR