Q9I0M3

PR
Gene name
ftsK (PA2615)
Protein name
DNA translocase FtsK
Names
Species
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG Pathway
pae:PA2615
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-53 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

9 structures for Q9I0M3

Entry ID Method Resolution Chain Position Source
2IUT X-ray 225 A A/B 247-811 PDB
2IUU X-ray 290 A A/B/C/D/E/F 247-728 PDB
2J5O NMR - A 742-811 PDB
2VE8 X-ray 140 A A/B/C/D/E/F/G/H 739-811 PDB
2VE9 X-ray 190 A A/B/C/D/E/F 739-811 PDB
6T8B EM 365 A A/B/C/D/E/F 247-728 PDB
6T8G EM 434 A A/B/C/D/E/F 247-728 PDB
6T8O EM 399 A A/B/C/D/E/F 247-728 PDB
AF-Q9I0M3-F1 Predicted AlphaFoldDB

No variants for Q9I0M3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9I0M3

No associated diseases with Q9I0M3

6 regional properties for Q9I0M3

Type Name Position InterPro Accession
domain Tubulin/FtsZ, GTPase domain 35 - 240 IPR003008-1
domain Tubulin/FtsZ, GTPase domain 241 - 262 IPR003008-2
domain Tubulin/FtsZ, 2-layer sandwich domain 236 - 353 IPR018316
conserved_site Cell division protein FtsZ, conserved site 66 - 100 IPR020805-1
conserved_site Cell division protein FtsZ, conserved site 119 - 140 IPR020805-2
domain Cell division protein FtsZ, C-terminal 251 - 344 IPR024757

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
  • Located at the septum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

4 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
cellular response to antibiotic Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRRKNSDLKD STTASHAAAW RQQLHSRLKE GVLIALGALC LYLWMALLTY DSADPSWSHS
70 80 90 100 110 120
SQVDQVQNAA GRLGAVSADI LFMTLGYFAY LFPLLLGIKT WQVFRRRNLP WEWNTWLFSW
130 140 150 160 170 180
RLVGLIFLIL AGSALAYIHF HASGHMPASA SAGGAIGQSL GRVAVDALNV QGSTLVFFAL
190 200 210 220 230 240
FLFGLTVFAD LSWFKVMDVT GKITLDFFEL IQNAFNRWMG ARAERKQLVA QLREVDERVA
250 260 270 280 290 300
EVVAPSVPDR REQSKAKERL LEREEALAKH MSEREKRPPP KIDPPPSPKA PEPSKRVLKE
310 320 330 340 350 360
KQAPLFVDTA VEGTLPPLSL LDPAEVKQKS YSPESLEAMS RLLEIKLKEF GVEVSVDSVH
370 380 390 400 410 420
PGPVITRFEI QPAAGVKVSR ISNLAKDLAR SLAVISVRVV EVIPGKTTVG IEIPNEDRQM
430 440 450 460 470 480
VRFSEVLSSP EYDEHKSTVP LALGHDIGGR PIITDLAKMP HLLVAGTTGS GKSVGVNAML
490 500 510 520 530 540
LSILFKSTPS EARLIMIDPK MLELSIYEGI PHLLCPVVTD MKEAANALRW SVAEMERRYR
550 560 570 580 590 600
LMAAMGVRNL AGFNRKVKDA EEAGTPLTDP LFRRESPDDE PPQLSTLPTI VVVVDEFADM
610 620 630 640 650 660
MMIVGKKVEE LIARIAQKAR AAGIHLILAT QRPSVDVITG LIKANIPTRI AFQVSSKIDS
670 680 690 700 710 720
RTILDQGGAE QLLGHGDMLY LPPGTGLPIR VHGAFVSDDE VHRVVEAWKL RGAPDYIEDI
730 740 750 760 770 780
LAGVDEGGGG GGSFDGGDGS GEGSEDDPLY DEAVRFVTES RRASISAVQR KLKIGYNRAA
790 800 810
RMIEAMEMAG VVTPMNTNGS REVIAPAPVR D