Q9HZE0
Gene name |
gdhB (PA3068) |
Protein name |
NAD-specific glutamate dehydrogenase |
Names |
NAD-GDH, NAD(+)-dependent glutamate dehydrogenase |
Species |
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
KEGG Pathway |
pae:PA3068 |
EC number |
1.4.1.2: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9HZE0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9HZE0-F1 | Predicted | AlphaFoldDB |
No variants for Q9HZE0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9HZE0 | |||||
No associated diseases with Q9HZE0
No regional properties for Q9HZE0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9HZE0 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 1.4.1.2 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| glutamate dehydrogenase (NAD+) activity | Catalysis of the reaction: L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glutamate catabolic process to 2-oxoglutarate | The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including 2-oxoglutarate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAFFTAASKA | DFQHQLQTAL | AQHLGDKALP | QVTLFAEQFF | SLISLDELTQ | RRLSDLVGCT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LSAWRLLERF | DRDQPEVRVY | NPDYEKHGWQ | STHTAVEVLH | PDLPFLVDSV | RMELNRRGYS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IHTLQTNVLS | VRRSAKGELK | EILPKGSQGK | DVSQESLMYL | EIDRCAHAGE | LRALEKAILE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VLGEVRVTVA | DFEPMKAKAR | ELLTWLGKAK | LKVPAEELKE | VRSYLEWLLD | NHFTFLGYEE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FSVADEADGG | RMVYDEKSFL | GLTRLLRAGL | SKDDLHIEDY | AVAYLREPVL | LSFAKAAHPS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RVHRPAYPDY | VSIRELDGKG | RVIRECRFMG | LFTSSVYNES | VNDIPFIRGK | VAEVMRRSGF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DTKAHLGKEL | AQVLEVLPRD | DLFQTPVDEL | FSTALAIVRI | QERNKIRVFL | RKDPYGRFCY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| CLAYVPRDVY | STETRLKIQQ | VLMERLQASD | CEFWTFFSES | VLARVQFILR | VDPKSRIDID |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PARLEEEVIQ | ACRSWQDDYS | SLVVENLGEA | KGTNVLADFP | KGFPAGYRER | FAPHFAVVDL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| QHLLSLSEQR | PLVMSFYQPL | AQGEQQLHCK | LYHADTPLAL | SDVLPILENL | GLRVLGEFPY |
| 610 | 620 | 630 | 640 | 650 | 660 |
| RLRHQNGREY | WIHDFAFTYA | EGLDVDIQQL | NEILQDAFVH | IVSGDAENDA | FNRLVLTANL |
| 670 | 680 | 690 | 700 | 710 | 720 |
| PWRDVALLRA | YARYLKQIRL | GFDLGYIASA | LNAHTDIARE | LVRLFKTRFY | LARKLTAEDL |
| 730 | 740 | 750 | 760 | 770 | 780 |
| EDKQQKLEQA | ILGALDEVQV | LNEDRILRRY | LDLIKATLRT | NFYQPDGNGQ | NKSYFSFKFN |
| 790 | 800 | 810 | 820 | 830 | 840 |
| PKAIPELPRP | VPKYEIFVYS | PRVEGVHLRG | GKVARGGLRW | SDREEDFRTE | VLGLVKAQQV |
| 850 | 860 | 870 | 880 | 890 | 900 |
| KNAVIVPVGA | KGGFVPRRLP | LGGSRDEIQA | EAIACYRIFI | SGLLDITDNL | KEGEVVPPAN |
| 910 | 920 | 930 | 940 | 950 | 960 |
| VVRHDEDDPY | LVVAADKGTA | TFSDIANGIA | AEYGFWLGDA | FASGGSAGYD | HKGMGITAKG |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| AWVSVQRHFR | ERGIDVQKDN | ISVIGIGDMA | GDVFGNGLLM | SDKLQLVAAF | NHMHIFIDPN |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| PDAASSFVER | QRLFNLPRSS | WADYDAKLIS | AGGGIFLRSA | KSIAITPEMK | ARFDIQADRL |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| APTELIHALL | KAPVDLLWNG | GIGTYVKSSK | ETHADVGDKA | NDGLRVDGRE | LRAKVVGEGG |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| NLGMTQLARV | EFGLHGGANN | TDFIDNAGGV | DCSDHEVNIK | ILLNEVVQAG | DMTEKQRNAL |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| LVKMTDAVGA | LVLGNNYKQT | QALSLAQRRA | RERIAEYKRL | MGDLEARGKL | DRALEFLPSD |
| 1270 | 1280 | 1290 | 1300 | 1310 | 1320 |
| EELAERISAG | QGLTRAELSV | LISYSKIDLK | ESLLKSLVPD | DDYLTRDMET | AFPALLAEKF |
| 1330 | 1340 | 1350 | 1360 | 1370 | 1380 |
| GDAMRRHRLK | REIVSTQIAN | DLVNHMGITF | VQRLKESTGM | SAANVAGAYV | IVRDVFHLPH |
| 1390 | 1400 | 1410 | 1420 | 1430 | 1440 |
| WFRQIENLDY | QVPADIQLTL | MDELMRLGRR | ATRWFLRSRR | NELDAARDVA | HFGPRIAALG |
| 1450 | 1460 | 1470 | 1480 | 1490 | 1500 |
| LKLNELLEGP | TRELWQARYQ | TYVDAGVPEL | LARMVAGTSH | LYTLLPIIEA | SDVTGQDTAE |
| 1510 | 1520 | 1530 | 1540 | 1550 | 1560 |
| VAKAYFAVGS | ALDLTWYLQQ | ITNLPVENNW | QALAREAFRD | DLDWQQRAIT | VSVLQMQDGP |
| 1570 | 1580 | 1590 | 1600 | 1610 | |
| KEVEARVGLW | LEQHLPLVER | WRAMLVELRA | ASGTDYAMYA | VANRELMDLA | QSSQHGVCIP |