Q9HXV3

PR
Gene name
ppc
Protein name
Phosphoenolpyruvate carboxylase
Names
PEPC, PEPCase
Species
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG Pathway
pae:PA3687
EC number
4.1.1.31: Carboxy-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

14-87 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9HXV3

Entry ID Method Resolution Chain Position Source
AF-Q9HXV3-F1 Predicted AlphaFoldDB

No variants for Q9HXV3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9HXV3

No associated diseases with Q9HXV3

2 regional properties for Q9HXV3

Type Name Position InterPro Accession
active_site Phosphoenolpyruvate carboxylase, Lys active site 136 - 147 IPR018129
active_site Phosphoenolpyruvate carboxylase, His active site 536 - 548 IPR033129

Functions

Description
EC Number 4.1.1.31 Carboxy-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

2 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
phosphoenolpyruvate carboxylase activity Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-.

3 GO annotations of biological process

Name Definition
carbon fixation A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates).
oxaloacetate metabolic process The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle.
tricarboxylic acid cycle A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPEIDARLRE DVHQLGELLG DTIREQYGPR FLDKIELIRK GAKAARRGSA EGAQQLTATL
70 80 90 100 110 120
DGLEEDELLP VARAFNQFLN LANIAEQYHR IRRRRPNEPE PFENLVLEEL LGRLKDAGHA
130 140 150 160 170 180
PGQLARQLAG LEIELVLTAH PTEVARRTLI QKYDAITAQL AAKDHADLLP EERSRIQQRL
190 200 210 220 230 240
QRLVAEAWHT DEIRKVRPTP VDEAKWGFAV IEHSLWQALP NVLRHVDEVL LRSTGERLPL
250 260 270 280 290 300
TAAPLRFASW MGGDRDGNPN VTASVTREVL LLARWMAADL YLRDIDRLAA ELSMQQASPQ
310 320 330 340 350 360
LLARVGDSAE PYRALLKQLR ERLRVTRNWT HQALAGEVPA AEGVLEHNRD LVEPLQLCHE
370 380 390 400 410 420
SLHACGMGVI ADGALLDCLR RAATFGLFLV RLDVRQDSAR HAAALSEITE YLELGSYDEW
430 440 450 460 470 480
DEKTRLEFLL EELNSRRPLL PAHYQPSADT AEVLATCRAI AAAPPASLGS YVISMAGQPS
490 500 510 520 530 540
DVLAVQLLLK ESGVDWPMRV VPLFETLDDL DNAGPCMERL LTLPGYRSRL SGVQEVMIGY
550 560 570 580 590 600
SDSAKDAGTL TAAWAQYRAQ EKLVEICRQH EVELLLFHGR GGTVGRGGGP AHAAILSQPP
610 620 630 640 650 660
GSVAGRFRVT EQGEMIRFKF GLPDIAEQNL NLYLAAVLEA TLMPPPAPEP AWRAQMDRLA
670 680 690 700 710 720
KDALLAYRRV VRDDPQFVEY FRLATPEQEL GRLPLGSRPA KRREGGVESL RAIPWIFAWT
730 740 750 760 770 780
QTRLMLPAWL GWETALLNAI ERGEGALLGQ MREQWPFFTT RIDMLEMVLA KADADIARLY
790 800 810 820 830 840
DERLVPLELR PLGRRLRDLL SQAVRVVLGL TGQSLLLAHA SETRESISVR NSYLDPLHLL
850 860 870
QAELLARSRR CRGDACGGLE QALLVTVAGV AAGLRNTG