Q9HXI1

PR
Gene name
secD
Protein name
Protein translocase subunit SecD
Names
Species
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG Pathway
pae:PA3821
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

128-201 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9HXI1

Entry ID Method Resolution Chain Position Source
AF-Q9HXI1-F1 Predicted AlphaFoldDB

No variants for Q9HXI1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9HXI1

No associated diseases with Q9HXI1

2 regional properties for Q9HXI1

Type Name Position InterPro Accession
conserved_site Protein-export membrane protein SecD/SecF/SecDF, conserved site 117 - 141 IPR022646
domain SecD export protein N-terminal TM domain 2 - 104 IPR027398

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
protein-transporting ATPase activity Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated.

4 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
protein transport by the Sec complex The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLNKYPLWKY LLILAVLAVG FIYSAPNLYP DDPAVQISGA STALQVTQAD VDRAAKALTD
70 80 90 100 110 120
AGIAVKADSL SKKGGLIRLV KQDDQLPAKE VVRRTLGDDY VVALNLAQTT PEWLRKLGGS
130 140 150 160 170 180
PMKLGLDLSG GVHFLLEVDM DKAVDARLKV YESEVKSLLR KERVRYRSLP IQDRAIQLGF
190 200 210 220 230 240
TDSESLDKAR SLIAKDFRDF EVVPEERNGL QVLRVALTQA KLAEIREYSI KQNLTTVRNR
250 260 270 280 290 300
VNELGVSEPL VQRQGANRIV VELPGVQDTA EAKRILGKTA NLEFRLAAEP DALKSATETF
310 320 330 340 350 360
EFREPRRPPV PLERGVIITG DQVTDASASF DENGRPQVNI RLDGHGGELM NRATRNNVGR
370 380 390 400 410 420
SMAVVFIEQK PVTRYTKQMV DGVEKEVAVP AFKEEKQIIS LATIQSPLGN QFRITGLDGP
430 440 450 460 470 480
GESSELALLL RAGGLAAPMY FAEERTIGPS LGADNIAKGI DASLWGMLFV SLFIIVIYRF
490 500 510 520 530 540
FGVIATVALA FNMVMLVALM SILGATLTLP GIAGIVLTMG MAVDANVLIF SRIREELANG
550 560 570 580 590 600
MSVQRAIHEG FNRAFTAILD ANLTSLLVGG ILYAMGTGPV KGFAVTMSLG IITSMFTAIM
610
VTRAMVNLIF GGRDFKKLWI