Q9HX17

PR
Gene name
PA4010
Protein name
Putative 3-methyladenine DNA glycosylase
Names
Species
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG Pathway
pae:PA4010
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

96-166 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9HX17

Entry ID Method Resolution Chain Position Source
AF-Q9HX17-F1 Predicted AlphaFoldDB

No variants for Q9HX17

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9HX17

No associated diseases with Q9HX17

No regional properties for Q9HX17

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9HX17

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
alkylbase DNA N-glycosylase activity Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

1 GO annotations of biological process

Name Definition
base-excision repair In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSRDPILSLP WPDARPLPDT FFDRDALLVA RELLGKVIRH RQGNLWLAAR IIETEAYYLE
70 80 90 100 110 120
EKGSHASLGY TEKRKALFLD GGHIYMYYAR GGDSLNFSAG GPGNAVLIKS GHPWLDRISD
130 140 150 160 170 180
HTALERMQSL NPDSQGRPRE IGRLCAGQTL LCKAMGLKVP EWDAQRFDPQ RLFVDDVGER
190 200 210 220 230
PSQVIQAARL GIPKGRDEHL PYRFVDAAFA AFCTRNPLRR GQVAGRDYHL LGHQDPHLQ