Q9HVF1

PR
Gene name
mqo2
Protein name
Probable malate:quinone oxidoreductase 2
Names
MQO 2, Malate dehydrogenase [quinone] 2
Species
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG Pathway
pae:PA4640
EC number
1.1.5.4: With a quinone or similar compound as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

10-85 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9HVF1

Entry ID Method Resolution Chain Position Source
AF-Q9HVF1-F1 Predicted AlphaFoldDB

No variants for Q9HVF1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9HVF1

No associated diseases with Q9HVF1

No regional properties for Q9HVF1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9HVF1

Functions

Description
EC Number 1.1.5.4 With a quinone or similar compound as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
malate dehydrogenase (menaquinone) activity Catalysis of the reaction: (S)-malate + a menaquinone = oxaloacetate + a menaquinol.
malate dehydrogenase (quinone) activity Catalysis of the reaction: (S)-malate + a quinone = oxaloacetate + a quinol.
oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

2 GO annotations of biological process

Name Definition
ethanol oxidation An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate.
tricarboxylic acid cycle A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAQNDHETVD MLLVGAGIMS ATLAVLLKEL DPNLKMEVVE LQESGAIESS NPWNNAGTGH
70 80 90 100 110 120
AGLCELNYTP QSADGSIDIK KAVGINTMFE VSKQFWSHLV AKGTFGSPKT FINPVPHLSF
130 140 150 160 170 180
VRGSEGIAYL KKRFESLTKH HAFETMVYSE DKATLAEWMP LMMPGRPADE AIAATRVEGG
190 200 210 220 230 240
TDVNFGALTN QLLQHLAQQP GAQIRYNQKV THLRRADNGW RVTVKDTRNG GDREIQARFV
250 260 270 280 290 300
FLGAGGGALP LLQLSGIPEG KGFGGFPVSG QWLRCDNPEI VKQHQAKVYS QAEVGSPPMS
310 320 330 340 350 360
VPHLDTRVVD GKKSLLFGPY AGFSTKFLRH GSFLDLPLSV RPGNILPMLS VARDNMDLTR
370 380 390 400 410 420
YLIGQVMQSP EQRLEALRKF YPEARAEDWR LEVAGQRVQI IKKDPKKGGI LQFGTELVAA
430 440 450 460 470 480
HDGSIAALLG ASPGASVTVS IMLGLIERCF PEQARSPEWS AKLKEIFPAR EKELESDAEL
490 500
YRSVSSRCSE VLELTAKNDV QAPVNAE