Q9HUL9
Gene name |
miaA (PA4945) |
Protein name |
tRNA dimethylallyltransferase |
Names |
Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase |
Species |
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
KEGG Pathway |
pae:PA4945 |
EC number |
2.5.1.75: Transferring alkyl or aryl groups, other than methyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
4 structures for Q9HUL9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 3CRM | X-ray | 190 A | A | 1-323 | PDB |
| 3CRQ | X-ray | 220 A | A | 1-323 | PDB |
| 3CRR | X-ray | 190 A | A | 1-323 | PDB |
| AF-Q9HUL9-F1 | Predicted | AlphaFoldDB |
No variants for Q9HUL9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9HUL9 | |||||
No associated diseases with Q9HUL9
No regional properties for Q9HUL9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9HUL9 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.5.1.75 | Transferring alkyl or aryl groups, other than methyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| tRNA dimethylallyltransferase activity | Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA modification | The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSLPPAIFL | MGPTAAGKTD | LAMALADALP | CELISVDSAL | IYRGMDIGTA | KPSRELLARY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PHRLIDIRDP | AESYSAAEFR | ADALAAMAKA | TARGRIPLLV | GGTMLYYKAL | LEGLADMPGA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DPEVRAAIEA | EAQAEGWEAL | HRQLAEVDPE | SAARIHPNDP | QRLMRALEVY | RLGGVSMSDL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RRRQSAEKAD | FDASGRNQLP | YTVAQLAIAP | EQRQVLHARI | AQRFRQMLEQ | GFIAEVEALH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ARSDLHAGLP | SIRAVGYRQV | WDYLDGKLSY | AEMTERGIIA | TRQLAKRQFT | WLRSWSHLHW |
| 310 | 320 | ||||
| MDSLAGDNLP | RALKYLKTVS | ILA |