Q9HIX3
Gene name |
eif2a |
Protein name |
Translation initiation factor 2 subunit alpha |
Names |
aIF2-alpha, eIF-2-alpha |
Species |
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) |
KEGG Pathway |
tac:Ta1203 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9HIX3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9HIX3-F1 | Predicted | AlphaFoldDB |
No variants for Q9HIX3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9HIX3 | |||||
No associated diseases with Q9HIX3
4 regional properties for Q9HIX3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translation elongation factor P/YeiP, central | 69 - 128 | IPR001059 |
| domain | Translation elongation factor, KOW-like | 7 - 62 | IPR013185 |
| conserved_site | Translation elongation factor P/YeiP, conserved site | 152 - 171 | IPR013852 |
| domain | Elongation factor P, C-terminal | 131 - 186 | IPR015365 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNIKPLPDNG | DLVVVKITEV | KNFGANGVLE | EYPGVEGYIH | ISEVATGWVK | HIRSYLREGQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RVVCKVIGVN | PERKVVDLSL | KRVNQHQSRE | KIAEWKNEQK | ADKLFEIVCS | RLNRNPEECK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EQFGRRLVEL | FGTLFAAFES | AAQSNGEWLP | EMNGDWKNVF | VEIAKENITI | PEVSVSGYFE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VYSLASDGVE | RIKEVLTIPE | DTGKVELEYV | GAPRYRIVVK | DKDYKKAEEI | LKKVVQIVNE |
| 250 | |||||
| KAKKLQVEVE | FNKQ |