Q9HGQ3

PR
Gene name
cis4 (SPAC17D4.03c)
Protein name
Probable zinc transporter cis4
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPAC17D4.03c
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

490-564 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9HGQ3

Entry ID Method Resolution Chain Position Source
AF-Q9HGQ3-F1 Predicted AlphaFoldDB

17 variants for Q9HGQ3

Variant ID(s) Position Change Description Diseaes Association Provenance
I_4729004_C_T 19 V>I No Jeffares_SNPs
I_4728988_T_C 24 Q>R No Jeffares_SNPs
I_4728614_C_T 149 D>N No Jeffares_SNPs
I_4728566_C_T 165 A>T No Jeffares_SNPs
I_4728544_A_C 172 V>G No Jeffares_SNPs
I_4728439_T_C 207 Y>C No Jeffares_SNPs
I_4728357_A_T 234 F>L No Jeffares_SNPs
I_4728344_G_A 239 L>F No Jeffares_SNPs
I_4728214_G_A 282 A>V No Jeffares_SNPs
I_4728203_C_T 286 A>T No Jeffares_SNPs
I_4728122_T_G 313 I>L No Jeffares_SNPs
I_4728073_A_G 329 I>T No Jeffares_SNPs
I_4727554_T_G 502 N>T No Jeffares_SNPs
I_4727523_A_C 512 D>E No Jeffares_SNPs
I_4727486_C_T 525 D>N No Jeffares_SNPs
I_4727461_G_T 533 T>N No Jeffares_SNPs
I_4727386_C_T 558 C>Y No Jeffares_SNPs

No associated diseases with Q9HGQ3

No regional properties for Q9HGQ3

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9HGQ3

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane; Multi-pass membrane protein
  • Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
cytoplasmic vesicle A vesicle found in the cytoplasm of a cell.
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
metal ion transmembrane transporter activity Enables the transfer of metal ions from one side of a membrane to the other.
zinc ion transmembrane transporter activity Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.

4 GO annotations of biological process

Name Definition
cellular zinc ion homeostasis Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell.
metal ion transport The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
zinc ion import into Golgi lumen The directed import of zinc(2+) from the cytosol across the Golgi membrane into the Golgi lumen.
zinc ion import into organelle The directed import of zinc(2+) from the cytosol, across an organelle membrane, into the organelle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNVNSSAFER TNRFPSFPVL KDDQKTSSDS IAAAKKKDLL SLISSKSLLS SETLGWFSVI
70 80 90 100 110 120
CAFSITGSGL EVNTMSIPFY LIFGIFAFVS FTTQYLGIYS FSFQPFQLLN VIIASLSMVF
130 140 150 160 170 180
ITLGAFVLGT LDTTCLLLLA FKLFFIRNDP TPFNARSANL KNYIAFPICL FVINHILILL
190 200 210 220 230 240
GYFQCSYSVF YASVFYILLG VFIRVFYLVN KEKFEKKELA FLFSSIVVAC LIQFNVLPLG
250 260 270 280 290 300
TINLSVTRFT ILCFMQIFCI NWDGIARIQF YLGKFDISLI MALISAIINK TASQNSIKII
310 320 330 340 350 360
SCLYQVGFCF FKIGSSITAN LKLPDNSRIY RLYNDFIVNG VLADKESRSI FYFFLLNVSY
370 380 390 400 410 420
MFVQVIYGLW TNSLGLISDA IHMAFDCIAI LVGLVATTLA KMPLNYAYPF GFAKIEALSG
430 440 450 460 470 480
FTNGIFLVLI SFSIVGEALY RLFHPPQMNT DQLLLVSFLG LVVNLVGILA FNHGHNHDHG
490 500 510 520 530 540
SHHHHSHSNH SMCLPNTTND INIFEEFEEE KDNVEAQKMG YTNDDHVSQH EHTHENSQEH
550 560 570 580 590 600
HHEHNHNHDH IHKYNEKCDH ESISLQNLDN DHHCHHHHEN HNMHGIFLHI IADTMGSVGV
610 620 630 640 650 660
IVSTILIQWF SWTGFDPLAS LIIAALIFVS VLPLIKDSAK NLLSVTDPES EYLLKQCLSN
670 680 690 700 710 720
ISLSNSVISL SNPKFWTNER GEVYGILHIQ VSIDGDLNVV RNEVFRKLSI AVPNLKHICI
730
QSERPNNCWC GK