Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9HFE6

Entry ID Method Resolution Chain Position Source
AF-Q9HFE6-F1 Predicted AlphaFoldDB

No variants for Q9HFE6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9HFE6

No associated diseases with Q9HFE6

1 regional properties for Q9HFE6

Type Name Position InterPro Accession
conserved_site Oxysterol-binding protein, conserved site 134 - 145 IPR018494

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
ribosome biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MELEKRIYVG GLSSSIESSD LESRFSRFGS VSNLEIINKS TPVGTIQRFA YLNFRTDEDK
70 80 90 100 110 120
WQKCKSYLSN ATFKGSKLRI EEARPYYLVK LQQEKKIADL QSTNNDEKNE DHSSKVDLED
130 140 150 160 170 180
PVFHGEIIVP GKHSKNMQVV TDSDVRKDPP RKGWKKGPYG RAIVVLRMYN KNTKKTRFFY
190 200 210 220 230 240
PLGKNCLQKL WGRVETNMDN TTAFYDSDHD EYVSYGGKRA SRDKIRMQAK LGIKASTQKD
250 260 270 280 290 300
DNDFELLNNT TGEIEVTKEL NEEQLDALRK KDKDTAASVL AELFGSENTE EIDTVSKTSG
310 320 330 340 350 360
VLELDNDSTN NFQKEGLDEQ DNLQKEESVH IDVPAEFEAF DERTAVVNVD NLKEMFSSNA
370 380 390 400 410 420
QDTSKFSLFG NENGVGEESE MESEIDDRNY ETMEEEADGE TPLAIVKASS GTKGWPKMFT
430 440 450 460 470
LPNPSSLFQP GNEDYTSREA LESWWSENRL FLTRDYKRKR KDAVKRQRRA HEKRIRLV