Q9HDX1

PR
Gene name
SPAPB1A11.04c
Protein name
Uncharacterized transcriptional regulatory protein PB1A11.04c
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPAPB1A11.04c
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-109 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9HDX1

Entry ID Method Resolution Chain Position Source
AF-Q9HDX1-F1 Predicted AlphaFoldDB

13 variants for Q9HDX1

Variant ID(s) Position Change Description Diseaes Association Provenance
I_2988159_T_G 91 I>L No Jeffares_SNPs
I_2988078_G_T 118 P>T No Jeffares_SNPs
I_2988071_C_T 120 S>N No Jeffares_SNPs
I_2987838_G_A 198 P>S No Jeffares_SNPs
I_2987667_T_A 255 M>L No Jeffares_SNPs
I_2987655_T_C 259 T>A No Jeffares_SNPs
I_2987648_G_A 261 S>L No Jeffares_SNPs
I_2987499_G_A 311 P>S No Jeffares_SNPs
I_2987451_A_G 327 S>P No Jeffares_SNPs
I_2987370_A_G 354 S>P No Jeffares_SNPs
I_2987115_T_C 439 T>A No Jeffares_SNPs
I_2986535_C_G 632 S>T No Jeffares_SNPs
I_2986417_C_A 671 E>D No Jeffares_SNPs

No associated diseases with Q9HDX1

2 regional properties for Q9HDX1

Type Name Position InterPro Accession
domain Zn(2)Cys(6) fungal-type DNA-binding domain 18 - 62 IPR001138
domain Transcription factor domain, fungi 128 - 400 IPR007219

Functions

Description
EC Number
Subcellular Localization
  • Nucleus membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
nuclear membrane Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
RNA polymerase II cis-regulatory region sequence-specific DNA binding Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIAAVEKDAV PRKRRVISQV SQACIRCRQK KIKCSGEKPS CQACSNNKVE CIWPDRPNMR
70 80 90 100 110 120
GKKPSSAART LSPLTGIVQP YLGSHPFSPT ILSPSSPNMD FTYSINSFGD YQKQLRLPTS
130 140 150 160 170 180
RKLLQLWDIF LKTSYTELFG IFNKAQITSQ IASDTAPPVL VLCICAHAAR FSQEEVNRFK
190 200 210 220 230 240
SSTAASDYYA NQAFSLLPCR FQDISLTNIT CLLLLCLIEL GSCRGAKAWL LLGMALRMVD
250 260 270 280 290 300
SLDLGNEIND NPLTMGSNTV SWTEAEQKRR VYWACFFVER LLSTGYMAPS KLRSLSLSLQ
310 320 330 340 350 360
KTSIQLPCPE PNFLFNQPIL TELFDGSLPE NTQSDTTSMA PYQRSLQLEF MTGSLIRLSN
370 380 390 400 410 420
LWSEISRWAL CGGYTKDITP PWLNQSQFHR SFELLKAWHE NLPPRAVWSY TNYSAYSSPG
430 440 450 460 470 480
ESAGACYTFM HLLYHTTLTY LLRNVLDLFP EKSRQKSKLF SSVSQRFGQQ PPTVWMDMIL
490 500 510 520 530 540
DQVITSADFI TKLSKDPLNY IMSPFVGFSI LTAATIHMLL KFCVVNIDQN YISSSRLVHV
550 560 570 580 590 600
DHQILQDRSK YWKINQAMLV TLQRLYNFYR FQYLEEQSLY NFKIPGFPLC ILEYGIVEDQ
610 620 630 640 650 660
SMKSNPDLNS FSKELFSRGT NELLNNGDDT QSGNSTPAMG VSEIRTDTIL DEEVPVDPLI
670 680 690
TSILDDGRWW EEMFGSERKA GFKETVFEDM NGRSIRL