AiPD: Autoinhibited Protein Database

Q9H583

Gene name	HEATR1 (BAP28, UTP10)
Protein name	HEAT repeat-containing protein 1
Names	Protein BAP28, U3 small nucleolar RNA-associated protein 10 homolog
Species	Homo sapiens (Human)
KEGG Pathway	hsa:55127
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1152-1222 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1152-1222 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

4 structures for Q9H583

Entry ID	Method	Resolution	Chain	Position	Source
7MQ8	EM	360 A	LM	1-2144	PDB
7MQ9	EM	387 A	LM	1-2144	PDB
7MQA	EM	270 A	LM	1-2144	PDB
AF-Q9H583-F1	Predicted				AlphaFoldDB

1731 variants for Q9H583

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA345360971 rs1266969522	2	T>K		No	ClinGen TOPMed gnomAD
CA345360967 rs1266969522	2	T>M		No	ClinGen TOPMed gnomAD
CA1472664 rs752559522	3	S>F		No	ClinGen ExAC gnomAD
CA1472663 rs767336669	5	A>P		No	ClinGen ExAC TOPMed gnomAD
rs767336669 CA39712899	5	A>S		No	ClinGen ExAC TOPMed gnomAD
rs759587486 CA1472662	6	Q>R		No	ClinGen ExAC gnomAD
CA345360869 rs1326422044 CA345360870	7	Q>H		No	ClinGen TOPMed gnomAD
CA345360812 rs1239162508	11	L>F		No	ClinGen TOPMed gnomAD
CA1472660 rs766048913	12	A>P		No	ClinGen ExAC gnomAD
CA1472659 rs762570268	12	A>V		No	ClinGen ExAC gnomAD
CA345360790 rs1319785407	13	L>F		No	ClinGen gnomAD
CA345360791 rs1319785407	13	L>V		No	ClinGen gnomAD
CA1472656 rs141053386	14	P>S		No	ClinGen 1000Genomes ExAC gnomAD
rs200735956 CA1472655	16	S>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs200735956 CA345360754	16	S>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA345360745 rs1160324871	17	D>H		No	ClinGen gnomAD
rs1160324871 CA345360748	17	D>N		No	ClinGen gnomAD
rs1377280217 CA345360708	20	L>F		No	ClinGen TOPMed gnomAD
rs528420179 CA345360689	21	L>F		No	ClinGen 1000Genomes ExAC gnomAD
CA345360694 rs1470087571	21	L>S		No	ClinGen TOPMed gnomAD
CA39712858 rs1038573516	22	S>F		No	ClinGen TOPMed
CA1472650 rs749401605	23	R>G		No	ClinGen ExAC gnomAD
CA39712853 rs766365098	24	D>H		No	ClinGen Ensembl
CA345360664 COSM1185801 rs766365098	24	D>N	lung [Cosmic]	No	ClinGen cosmic curated Ensembl
rs752403855 CA1472647	25	E>G		No	ClinGen ExAC
rs756410208 CA1472648	25	E>K		No	ClinGen ExAC gnomAD
CA1472645 rs754955094	26	V>F		No	ClinGen ExAC gnomAD
CA1472646 rs754955094	26	V>I		No	ClinGen ExAC gnomAD
TCGA novel	27	A>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1472644 rs751489308	28	S>F		No	ClinGen ExAC gnomAD
rs1572057871 CA345360566	32	D>A		No	ClinGen Ensembl
CA345360549 rs1432663537	33	P>R		No	ClinGen gnomAD
CA345360556 rs762500785	33	P>S		No	ClinGen ExAC gnomAD
CA1472642 rs762500785	33	P>T		No	ClinGen ExAC gnomAD
CA345360544 rs1346836367	34	K>E		No	ClinGen gnomAD
rs1318896380 CA345360542	34	K>M		No	ClinGen gnomAD
CA1472639 rs764763618	36	A>V		No	ClinGen ExAC gnomAD
rs775703547 CA1472637	37	A>V		No	ClinGen ExAC gnomAD
rs1056443114 CA39712740	38	T>A		No	ClinGen TOPMed
rs939348909 CA39712727	39	I>V		No	ClinGen TOPMed gnomAD
CA1472636 rs772362857	41	R>G		No	ClinGen ExAC TOPMed gnomAD
rs1449499629 CA345360424	43	T>I		No	ClinGen TOPMed
rs771451183 CA1472633	44	A>S		No	ClinGen ExAC TOPMed gnomAD
rs771451183 CA345360421	44	A>T		No	ClinGen ExAC TOPMed gnomAD
CA345360383 rs1212442927	47	I>V		No	ClinGen gnomAD
rs769857743 CA1472612	49	C>Y		No	ClinGen ExAC gnomAD
rs1233542834 CA345359745	50	T>I		No	ClinGen TOPMed
rs757814368 CA1472610	54	E>K		No	ClinGen ExAC TOPMed gnomAD
CA1472608 rs746765386	56	L>F		No	ClinGen ExAC gnomAD
rs1416246979 CA345359549	57	G>E		No	ClinGen gnomAD
CA345359519 rs1167823062	58	I>T		No	ClinGen gnomAD
CA1472606 rs758253283	59	D>G		No	ClinGen ExAC
rs780058062 CA1472607	59	D>N		No	ClinGen ExAC gnomAD
CA39712125 rs1025640941	60	P>H		No	ClinGen TOPMed
rs1025640941 CA345359458	60	P>L		No	ClinGen TOPMed
TCGA novel	60	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1472604 rs778718727	61	S>F		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	62	F>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1481382048 CA345359375	64	Q>E		No	ClinGen gnomAD
CA345359382 rs1481382048	64	Q>K		No	ClinGen gnomAD
rs756750583 CA1472603	65	F>S		No	ClinGen ExAC gnomAD
rs753367978 CA1472602	66	E>D		No	ClinGen ExAC gnomAD
CA1472601 rs755803997	67	A>G		No	ClinGen ExAC gnomAD
rs755803997 CA1472600	67	A>V		No	ClinGen ExAC gnomAD
CA1472599 rs199653340	68	P>L		No	ClinGen 1000Genomes ExAC gnomAD
CA345359227 rs1335520924	73	L>Q		No	ClinGen gnomAD
CA39712084 rs368023463	75	K>E		No	ClinGen Ensembl
rs1222164898 CA345359179	76	T>S		No	ClinGen gnomAD
CA345359150 rs1460626340	79	R>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA345359148 rs773705501	79	R>P		No	ClinGen ExAC TOPMed gnomAD
COSM906062 CA1472596 rs773705501	79	R>Q	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA345359130 rs1439318550	82	Q>*		No	ClinGen TOPMed
CA345359129 rs1439318550	82	Q>E		No	ClinGen TOPMed
CA39712071 rs935301093	86	V>I		No	ClinGen TOPMed gnomAD
CA345359060 rs1462389626	87	N>S		No	ClinGen gnomAD
CA1472593 rs761927377	88	K>Q		No	ClinGen ExAC gnomAD
TCGA novel	89	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1472592 rs768993090	90	L>M		No	ClinGen ExAC TOPMed gnomAD
rs951440620 CA39712062	90	L>W		No	ClinGen TOPMed
rs372793751 CA345358972	94	I>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs372793751 CA1472590	94	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA345358956 rs1408255734	95	S>A		No	ClinGen gnomAD
CA345358943 rs1190325970	95	S>L		No	ClinGen TOPMed gnomAD
CA345358938 rs1452313605	96	L>V		No	ClinGen gnomAD
rs374661960 CA39712040	98	L>F		No	ClinGen ESP
TCGA novel	99	I>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs771832271 CA1472588	99	I>M		No	ClinGen ExAC gnomAD
TCGA novel	101	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1472587 rs745680073	102	S>L		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	103	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA39712029 rs911693962	104	Y>C		No	ClinGen Ensembl
CA39712026 rs1051631805	105	F>L		No	ClinGen gnomAD
CA39712019 rs757191202	105	F>L		No	ClinGen ExAC TOPMed gnomAD
CA1472584 rs748767159	109	P>S		No	ClinGen ExAC gnomAD
TCGA novel	111	Q>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1233894712 CA345358696	111	Q>P		No	ClinGen gnomAD
TCGA novel	114	L>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345358622 rs1369090220	116	W>S		No	ClinGen gnomAD
CA345358599 rs1306018489	118	I>F		No	ClinGen TOPMed gnomAD
CA1472583 rs777333597	118	I>T		No	ClinGen ExAC TOPMed gnomAD
CA345358600 rs1306018489	118	I>V		No	ClinGen TOPMed gnomAD
rs1173952130 CA345358050	121	F>Y		No	ClinGen gnomAD
rs770898106 CA1472564	124	H>Q		No	ClinGen ExAC gnomAD
CA345358018 rs1172408251	124	H>Y		No	ClinGen gnomAD
CA39707855 rs1021958237	125	L>H		No	ClinGen TOPMed
rs749283266 CA1472563	126	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA345357999 rs1572055437	126	Y>H		No	ClinGen Ensembl
rs777703237 CA1472562	127	N>D		No	ClinGen ExAC gnomAD
CA1472561 rs544530055	127	N>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1472560 rs146181190	128	Q>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs146181190 CA1472559	128	Q>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1472558 rs754640629	129	D>H		No	ClinGen ExAC gnomAD
CA1472557 rs750792703	129	D>V		No	ClinGen ExAC TOPMed gnomAD
CA1472556 rs779199641	130	S>C		No	ClinGen ExAC gnomAD
CA39707819 rs775516568	130	S>N		No	ClinGen Ensembl
CA1472554 rs754328458	131	L>F		No	ClinGen ExAC gnomAD
CA39707806 rs1033415391	132	I>T		No	ClinGen TOPMed
CA1472552 rs184646465	132	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1472551 rs752767682	135	V>F		No	ClinGen ExAC gnomAD
CA345357940 rs1393905193	136	L>M		No	ClinGen TOPMed gnomAD
CA1472549 rs759744935	138	Y>C		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	140	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1472548 rs192876952	140	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs867330018 CA39707783	141	T>I		No	ClinGen Ensembl
rs1420161475 CA345357902	142	R>G		No	ClinGen gnomAD
rs1572055387 CA345357894	143	I>V		No	ClinGen Ensembl
rs1370970789 CA345357873	146	R>*		No	ClinGen gnomAD
CA1472545 rs775729831	146	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA345357870 rs1248705746	147	V>I		No	ClinGen TOPMed gnomAD
rs769748600 CA1472544	149	Q>E		No	ClinGen ExAC gnomAD
CA345357851 rs1216333595	149	Q>H		No	ClinGen TOPMed
CA345357848 rs1481204799	150	L>F		No	ClinGen gnomAD
TCGA novel	153	I>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1472543 rs747638987	154	N>S		No	ClinGen ExAC gnomAD
rs1006848033 CA39707735	156	S>T		No	ClinGen Ensembl
rs768338113 CA1472541	157	K>E		No	ClinGen ExAC TOPMed gnomAD
CA39707734 rs953856798	157	K>R		No	ClinGen gnomAD
CA39707720 rs368148863	160	W>C		No	ClinGen ESP
rs1572055350 CA345357750	162	W>*		No	ClinGen Ensembl
CA345357732 rs1330550797	164	L>V		No	ClinGen gnomAD
CA39707713 rs372923233	165	P>T		No	ClinGen Ensembl
rs779759770 CA1472539	166	V>I		No	ClinGen ExAC gnomAD
TCGA novel	167	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345357267 rs1239364868	168	Q>H		No	ClinGen gnomAD
rs1369826717 CA345357243	171	V>M		No	ClinGen gnomAD
rs887049487 CA39706959	172	P>L		No	ClinGen TOPMed gnomAD
TCGA novel	173	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1317640774 CA345357167	175	K>R		No	ClinGen gnomAD
CA1472520 rs576830922	177	T>N		No	ClinGen 1000Genomes ExAC gnomAD
rs61375816 CA1472518 RCV000966791	179	I>T		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs143912188 CA1472519	179	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA345357084 rs1420498377	181	H>Y		No	ClinGen gnomAD
rs749639043 CA1472516	183	Y>C		No	ClinGen ExAC gnomAD
CA1472515 rs142578249	184	K>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs756677371 CA1472514	184	K>R		No	ClinGen ExAC gnomAD
CA1472513 rs774665306	185	D>E		No	ClinGen ExAC TOPMed gnomAD
rs781728054 CA1472512	188	F>L		No	ClinGen ExAC gnomAD
rs1285698557 CA345356963	189	M>V		No	ClinGen gnomAD
rs1216729630 CA345356911	193	C>G		No	ClinGen gnomAD
CA345356875 rs1338687092	195	L>W		No	ClinGen TOPMed
CA345356871 rs1399502102	196	V>M		No	ClinGen TOPMed
CA345356849 rs1333345182	197	T>R		No	ClinGen TOPMed
rs751689075 CA1472510	198	K>E		No	ClinGen ExAC TOPMed gnomAD
rs781509057 CA1472493	202	V>I		No	ClinGen ExAC TOPMed gnomAD
rs374840477 CA1472492	204	A>S		No	ClinGen ESP ExAC gnomAD
rs1416808584 CA345356480	206	Y>*		No	ClinGen gnomAD
CA1472491 rs747034390	206	Y>C		No	ClinGen ExAC gnomAD
COSM1197291 CA1472489 rs758481863	207	P>L	lung [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA345356474 rs758481863	207	P>R		No	ClinGen ExAC TOPMed gnomAD
rs573497694 CA1472490	207	P>S		No	ClinGen 1000Genomes ExAC gnomAD
CA39706476 rs763138915	208	G>C		No	ClinGen TOPMed
CA1472487 rs765469165	208	G>D		No	ClinGen ExAC gnomAD
rs1172092585 CA345356457	209	S>N		No	ClinGen gnomAD
TCGA novel	210	S>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1415075805 CA345356426	212	Q>R		No	ClinGen gnomAD
TCGA novel	214	R>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1213066078 CA345356399	215	V>M		No	ClinGen TOPMed
CA345356333 rs1483346033	221	A>T		No	ClinGen TOPMed gnomAD
TCGA novel	223	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA39706464 rs982146643	224	I>V		No	ClinGen gnomAD
CA1472485 rs201547441	226	S>L		No	ClinGen ExAC TOPMed gnomAD
CA1472483 rs760724482	227	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1452348478 CA345356250	229	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs759130190 CA1472480	229	V>I		No	ClinGen ExAC TOPMed gnomAD
CA345356237 rs1279263406	231	A>V		No	ClinGen gnomAD
rs1572054022 CA345356216	234	V>G		No	ClinGen Ensembl
rs769692131 CA1472477	234	V>I		No	ClinGen ExAC gnomAD
TCGA novel	235	S>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs911096356 CA39706429	236	D>E		No	ClinGen TOPMed
CA345356206 rs1164888810	236	D>G		No	ClinGen TOPMed
CA1472476 rs777098427	236	D>H		No	ClinGen ExAC TOPMed gnomAD
rs146667999 CA1472475	237	N>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1166397542 CA345356200	237	N>S		No	ClinGen TOPMed gnomAD
rs371395131 CA1472473	240	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs1175167841 CA345356178	240	A>V		No	ClinGen gnomAD
rs1314426953 CA345356172	241	K>I		No	ClinGen TOPMed
TCGA novel	242	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	244	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1472468 rs375951592	245	Y>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs143920214 CA345356150	245	Y>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs375951592 CA39706416	245	Y>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs143920214 CA1472469	245	Y>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs143920214 CA1472470	245	Y>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs375951592 CA345356149	245	Y>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs777690146 CA1472467	246	I>T		No	ClinGen ExAC gnomAD
TCGA novel	247	Q>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1361891390 CA345356093	251	K>I		No	ClinGen gnomAD
rs1240577191 CA345356048	258	R>G		No	ClinGen TOPMed
rs752568839 CA345356042	259	A>P		No	ClinGen ExAC gnomAD
CA1472446 rs752568839	259	A>T		No	ClinGen ExAC gnomAD
CA1472445 rs753064763	260	A>T		No	ClinGen ExAC gnomAD
rs755012043 CA1472444	261	T>A		No	ClinGen ExAC TOPMed gnomAD
CA1472443 rs547078368	262	Y>H		No	ClinGen 1000Genomes ExAC gnomAD
rs1192733099 CA345356015	263	M>I		No	ClinGen TOPMed
rs147463795 CA1472441	263	M>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs1427804500 CA345356011	264	I>V		No	ClinGen gnomAD
rs750046474 CA1472440	265	I>L		No	ClinGen ExAC gnomAD
CA345356000 rs1184792420	265	I>M		No	ClinGen gnomAD
CA1472438 rs371280584	267	Q>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA39705973 rs201126687	267	Q>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs201126687 CA1472439	267	Q>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA345355975 rs1313290206	269	S>Y		No	ClinGen TOPMed gnomAD
CA345355973 rs1453115990	270	V>M		No	ClinGen TOPMed
CA39705944 rs376676358	273	T>I		No	ClinGen ESP gnomAD
rs772555932 CA1472435	274	M>T		No	ClinGen ExAC TOPMed gnomAD
CA39705936 rs776734380	281	S>L		No	ClinGen Ensembl
TCGA novel	283	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs561355125 CA1472433	285	Q>H		No	ClinGen 1000Genomes ExAC gnomAD
rs770985913 CA345355858	287	I>F		No	ClinGen ExAC gnomAD
TCGA novel	287	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs770985913 CA1472432	287	I>V		No	ClinGen ExAC gnomAD
rs749349189 CA1472431	288	K>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	292	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1472430 rs773442079	292	K>R		No	ClinGen ExAC gnomAD
CA345355810 rs1325581869	294	P>S		No	ClinGen TOPMed
rs1397640135 CA345355803	295	S>F		No	ClinGen TOPMed
CA345355792 rs1461301698	296	L>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1371264176 CA345355790	297	I>V		No	ClinGen gnomAD
rs1172806723 CA345355770	299	D>G		No	ClinGen gnomAD
CA1472428 rs781187454	300	G>E		No	ClinGen ExAC gnomAD
CA1472427 rs781187454	300	G>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA345355754 rs1424370682	301	L>I		No	ClinGen gnomAD
CA345355722 rs754958952	302	S>R		No	ClinGen ExAC gnomAD
rs1000929249 CA39705913	305	I>V		No	ClinGen gnomAD
rs1258537128 CA345355663	306	V>A		No	ClinGen gnomAD
CA345355660 rs1201384553	307	L>V		No	ClinGen gnomAD
CA345355558 rs1332506679	313	P>L		No	ClinGen TOPMed
CA345355576 rs1295088522	313	P>T		No	ClinGen TOPMed
rs779883088 CA345355538	314	E>D		No	ClinGen ExAC gnomAD
rs531264378 CA1472423	315	S>R		No	ClinGen 1000Genomes ExAC gnomAD
rs1230943337 CA345355471	318	K>E		No	ClinGen gnomAD
TCGA novel	319	K>=	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1472422 rs749945048	319	K>T		No	ClinGen ExAC gnomAD
rs763425291 CA1472393	323	H>L		No	ClinGen ExAC gnomAD
CA1472394 rs543299161	323	H>Y		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1472392 rs200588560	325	C>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA39705760 rs200588560	325	C>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1558192146 CA345355215	326	N>K		No	ClinGen Ensembl
CA1472391 rs557630891	326	N>S		No	ClinGen 1000Genomes ExAC gnomAD
CA1472390 rs761994088	327	V>G		No	ClinGen ExAC gnomAD
rs776956674 CA1472389	328	P>S		No	ClinGen ExAC gnomAD
TCGA novel	330	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1267375884 CA345355137	331	I>M		No	ClinGen gnomAD
rs539204282 CA1472387	331	I>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs372195004 CA1472388	331	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs775208742 CA1472386	332	T>A		No	ClinGen ExAC TOPMed gnomAD
CA345355127 rs1348012449	332	T>I		No	ClinGen gnomAD
CA345355128 rs1348012449	332	T>K		No	ClinGen gnomAD
rs1001042251 CA39705740	333	I>M		No	ClinGen Ensembl
CA345355114 rs1265855377	334	L>I		No	ClinGen gnomAD
rs772043034 CA1472385	335	H>N		No	ClinGen ExAC
CA1472384 rs141911723	335	H>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1472383 rs148138589	336	G>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA345355040 rs1301117754	340	T>A		No	ClinGen gnomAD
rs143741485 CA1472380	342	D>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1472379 rs201723577	343	V>I		No	ClinGen 1000Genomes ExAC gnomAD
rs780347148 CA1472377	345	P>R		No	ClinGen ExAC TOPMed gnomAD
CA345354981 rs1358861245	345	P>S		No	ClinGen gnomAD
CA345354970 rs1175182296	346	L>P		No	ClinGen TOPMed
CA39705675 rs375413643	346	L>V		No	ClinGen ESP TOPMed gnomAD
rs750898415 CA1472376	348	H>N		No	ClinGen ExAC TOPMed gnomAD
rs2794751 VAR_049329 CA1472374	348	H>R		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA1472375 rs750898415	348	H>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA1472373 rs761957349	349	Y>C		No	ClinGen ExAC gnomAD
rs144891600 CA39705638 CA345354939	350	M>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs144891600 CA1472372	350	M>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs764401410 CA1472371	352	P>S		No	ClinGen ExAC gnomAD
rs1264851351 CA345354891	355	V>I		No	ClinGen gnomAD
CA1472369 rs775787163	356	V>I		No	ClinGen ExAC gnomAD
rs1288183613 CA345354865	357	S>C		No	ClinGen TOPMed
CA345354870 rs1485157644	357	S>P		No	ClinGen gnomAD
CA1472368 rs367953651	358	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA345354851 rs1220752375	359	I>V		No	ClinGen gnomAD
CA1472367 RCV000909961 rs149968331	360	H>R		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA345354828 rs1269595568	361	H>R		No	ClinGen gnomAD
CA345354819 rs1226772610	362	V>I		No	ClinGen gnomAD
rs774231133 CA1472366	363	T>I		No	ClinGen ExAC TOPMed gnomAD
rs1450798828 CA345353992	366	E>G		No	ClinGen TOPMed
rs1378709347 CA345353974	367	T>I		No	ClinGen gnomAD
CA1472353 rs566412296	370	M>I		No	ClinGen 1000Genomes ExAC gnomAD
CA39704782 rs974608655	370	M>L		No	ClinGen TOPMed gnomAD
rs1450604396 CA345353930	371	D>G		No	ClinGen gnomAD
CA345353922 rs1378859379	372	G>S		No	ClinGen TOPMed
rs1360149989 CA345353913	372	G>V		No	ClinGen gnomAD
rs547782635 CA1472352	374	I>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1472351 COSM367008 rs767810463	375	Y>C	lung [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA1472350 rs759296237	376	K>R		No	ClinGen ExAC TOPMed gnomAD
CA1472349 rs774178054	378	H>D		No	ClinGen ExAC gnomAD
rs765950856 CA345353813	379	L>F		No	ClinGen gnomAD
COSM906055 CA345353823 rs1460526428	379	L>V	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs367603895 CA1472348	381	A>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs367603895 CA39704730	381	A>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA345353785 rs367603895	381	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA1472347 rs762941150	382	I>V		No	ClinGen ExAC gnomAD
rs773135508 CA1472346	384	T>K		No	ClinGen ExAC TOPMed gnomAD
CA345353761 rs773135508	384	T>R		No	ClinGen ExAC TOPMed gnomAD
rs769123642 CA1472345	385	K>E		No	ClinGen ExAC TOPMed gnomAD
COSM906054 rs769123642 CA39704727	385	K>Q	Variant assessed as Somatic; impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA1472344 rs536011790	386	I>V		No	ClinGen 1000Genomes ExAC gnomAD
CA345353727 rs1458983144	387	S>P		No	ClinGen gnomAD
rs1458983144 CA345353730	387	S>T		No	ClinGen gnomAD
rs1321246913 CA345353704	388	L>P		No	ClinGen gnomAD
rs1287954302 CA345353670	391	N>H		No	ClinGen TOPMed gnomAD
rs1287954302 CA345353672	391	N>Y		No	ClinGen TOPMed gnomAD
CA1472340 rs779489345	394	H>R		No	ClinGen ExAC gnomAD
rs993241928 CA39704667	397	A>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA345353584 rs1572052670	398	S>N		No	ClinGen Ensembl
rs1409888736 CA345353375	399	L>I		No	ClinGen TOPMed
rs1002088341 CA39703707	400	L>Q		No	ClinGen TOPMed gnomAD
rs761210681 CA1472318	402	E>G		No	ClinGen ExAC gnomAD
CA345353357 rs1157119919	402	E>K		No	ClinGen TOPMed
CA1472317 rs776267298	405	I>L		No	ClinGen ExAC gnomAD
CA345353333 rs776267298	405	I>V		No	ClinGen ExAC gnomAD
CA39703692 rs868715573	406	S>L		No	ClinGen Ensembl
CA1472315 rs746597368	407	Y>F		No	ClinGen ExAC gnomAD
CA39703686 rs919786919	407	Y>H		No	ClinGen gnomAD
rs1304122450 CA345353286	410	Q>R		No	ClinGen gnomAD
TCGA novel	413	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs775297342 CA1472314	414	D>G		No	ClinGen ExAC gnomAD
CA39703680 rs866515557	414	D>N		No	ClinGen TOPMed gnomAD
CA345353242 rs866515557	414	D>Y		No	ClinGen TOPMed gnomAD
CA1472313 rs771375166	415	S>C		No	ClinGen ExAC gnomAD
rs147493070 CA1472311	416	N>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA345353199 rs1301973674	417	K>N		No	ClinGen gnomAD
rs1369126985 CA345353188	418	V>A		No	ClinGen TOPMed gnomAD
rs1464416005 CA345353180	419	S>Y		No	ClinGen gnomAD
rs1360814041 CA345353174	420	L>V		No	ClinGen gnomAD
CA345353149 rs1375961801	422	N>S		No	ClinGen TOPMed
CA1472310 rs748162961	423	E>D		No	ClinGen ExAC TOPMed gnomAD
CA345353143 rs1176770420	423	E>K		No	ClinGen gnomAD
CA345353142 rs1176770420	423	E>Q		No	ClinGen gnomAD
rs78786861 CA1472308	424	Q>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1472306 rs751719289	425	F>L		No	ClinGen ExAC
CA1472305 rs766607585	426	L>P		No	ClinGen ExAC gnomAD
rs750285319 CA1472303	427	P>Q		No	ClinGen ExAC
CA345353077 rs758146296	427	P>S		No	ClinGen ExAC TOPMed gnomAD
rs758146296 CA1472304	427	P>T		No	ClinGen ExAC TOPMed gnomAD
CA345353070 rs1200224208	428	L>F		No	ClinGen gnomAD
CA1472302 rs765074918	428	L>P		No	ClinGen ExAC TOPMed gnomAD
CA39703646 rs200417112	430	R>K		No	ClinGen gnomAD
rs2564739 CA345353041	430	R>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs760284774 CA1472298	434	S>R		No	ClinGen ExAC gnomAD
CA345352985 rs1340740506	435	K>E		No	ClinGen gnomAD
CA1472297 rs574501045	435	K>R		No	ClinGen 1000Genomes ExAC gnomAD
CA529509110 rs1164601505	436	Y>*		No	ClinGen gnomAD
rs1370421225 CA345352936	436	Y>H		No	ClinGen gnomAD
CA1472280 rs764158257	439	T>A		No	ClinGen ExAC gnomAD
rs760233592 CA1472279	439	T>I		No	ClinGen ExAC gnomAD
rs764158257 CA345352900	439	T>P		No	ClinGen ExAC gnomAD
CA39703415 rs547451139	440	L>F		No	ClinGen Ensembl
rs1429021278 CA345352882	441	D>G		No	ClinGen TOPMed
TCGA novel	442	V>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs956227797 CA39703413	442	V>I		No	ClinGen TOPMed
CA1472278 rs752305136	443	V>L		No	ClinGen ExAC gnomAD
CA345352765 rs1220395794	449	K>R		No	ClinGen TOPMed gnomAD
rs1311221867 CA345352750	451	I>T		No	ClinGen gnomAD
rs375930921 CA1472273	451	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs777080330 CA1472272	452	A>V		No	ClinGen ExAC gnomAD
CA39703393 rs10925169	454	L>M		No	ClinGen gnomAD
CA345352720 rs1393129357	456	K>E		No	ClinGen gnomAD
CA345352709 rs201708653	457	Q>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1472270 rs201708653	457	Q>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs112914610 CA345352680	459	L>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1472269 rs112914610 RCV000905068	459	L>I		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA1472267 rs746047994	461	H>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs779027115 CA1472266	462	Q>R		No	ClinGen ExAC gnomAD
CA1472265 rs150934078	463	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs753618231 CA1472264	466	L>F		No	ClinGen ExAC gnomAD
CA345352545 rs1269110885	467	S>C		No	ClinGen gnomAD
CA1472262 rs376042124	468	T>A		No	ClinGen ESP ExAC gnomAD
rs752249631 CA1472261	468	T>I		No	ClinGen ExAC gnomAD
rs376042124 CA1472263	468	T>S		No	ClinGen ESP ExAC gnomAD
CA345352532 rs1287819556	469	S>G		No	ClinGen TOPMed gnomAD
rs1217068496 CA345352522	469	S>R		No	ClinGen gnomAD
rs1273063955 CA345352454	474	Q>R		No	ClinGen gnomAD
rs748040521 CA1472240	480	D>G		No	ClinGen ExAC gnomAD
TCGA novel	482	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs148909192 CA1472239	485	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs1182704457 CA345351755	487	L>V		No	ClinGen TOPMed gnomAD
rs765149081 CA39702727	490	P>L		No	ClinGen Ensembl
CA345351679 rs1332631858	491	L>P		No	ClinGen gnomAD
CA39702723 rs1031172450	492	A>D		No	ClinGen TOPMed gnomAD
rs144502500 CA1472238	492	A>P		No	ClinGen ESP ExAC TOPMed gnomAD
CA345351671 rs1031172450	492	A>V		No	ClinGen TOPMed gnomAD
rs753474949 CA1472236	493	P>L		No	ClinGen ExAC TOPMed gnomAD
rs753474949 CA1472237	493	P>R		No	ClinGen ExAC TOPMed gnomAD
rs1456325073 CA345351659	494	V>M		No	ClinGen TOPMed
rs1162496214 CA345351636	496	I>N		No	ClinGen TOPMed
CA1472233 rs764388654	499	M>I		No	ClinGen ExAC gnomAD
CA1472234 rs202190512	499	M>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs1472279920 CA345351537	501	H>R		No	ClinGen gnomAD
CA39702708 rs1039867640	504	K>E		No	ClinGen Ensembl
rs775937506 CA1472231	504	K>M		No	ClinGen ExAC gnomAD
rs1461662799 CA345351448	504	K>N		No	ClinGen gnomAD
CA345351454 rs775937506	504	K>R		No	ClinGen ExAC gnomAD
rs904090648 CA39702706	505	I>V		No	ClinGen TOPMed
CA345351415 rs1198078552	506	M>V		No	ClinGen gnomAD
CA1472229 rs759640931	509	S>L		No	ClinGen ExAC gnomAD
rs771178359 CA1472227	510	K>E		No	ClinGen ExAC gnomAD
TCGA novel	511	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1472201 rs770177219	512	G>D		No	ClinGen ExAC TOPMed gnomAD
rs376890423 CA1472202	512	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA345350656 rs1156624519	513	V>I		No	ClinGen gnomAD
rs1214469139 CA345350636	515	E>Q		No	ClinGen TOPMed
rs374469202 CA39701282	516	S>P		No	ClinGen Ensembl
rs907267379 CA39701269	517	F>C		No	ClinGen TOPMed
rs1391031431 CA345350603	518	I>V		No	ClinGen TOPMed gnomAD
TCGA novel	519	K>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs777699259 CA345350581	520	E>K		No	ClinGen TOPMed
CA345350583 rs777699259	520	E>Q		No	ClinGen TOPMed
CA345350571 rs1408711550	521	A>T		No	ClinGen TOPMed gnomAD
rs999439577 CA39701264	522	V>G		No	ClinGen Ensembl
rs1470411902 CA345350560	522	V>I		No	ClinGen TOPMed
CA39701261 rs867493254	524	A>V		No	ClinGen Ensembl
rs372480318 CA1472199	525	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA39701258 rs539775783	529	D>A		No	ClinGen 1000Genomes
rs768505125 CA1472198	529	D>N		No	ClinGen ExAC gnomAD
rs746866917 CA1472196	531	I>T		No	ClinGen ExAC gnomAD
CA345350465 rs1410513432	531	I>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA1472195 rs142765787	532	D>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs200359420 CA1472194	533	V>I		No	ClinGen 1000Genomes ExAC gnomAD
rs1218110659 CA345350430	536	S>L		No	ClinGen gnomAD
rs1284690036 CA345350429	537	A>T		No	ClinGen gnomAD
CA1472190 rs149485004 CA345350423	538	I>L		No	ClinGen ESP ExAC TOPMed gnomAD
COSM1501679 rs149485004 CA1472189	538	I>V	lung [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
rs755382653 CA1472188	541	F>S		No	ClinGen ExAC TOPMed gnomAD
rs79889770 CA39701216	542	E>*		No	ClinGen Ensembl
CA345350395 rs1455204439	542	E>G		No	ClinGen TOPMed gnomAD
rs750524140 CA1472165	543	I>T		No	ClinGen ExAC TOPMed gnomAD
rs1464866866 CA345350376	543	I>V		No	ClinGen TOPMed
CA1472163 rs367739362	547	H>Q		No	ClinGen ESP ExAC gnomAD
COSM3689450 rs1431845727 CA345350343	547	H>R	large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed
CA345350335 rs1203718161	548	F>L		No	ClinGen gnomAD
CA1472162 rs753971634	548	F>Y		No	ClinGen ExAC gnomAD
rs113875116 CA39700903	551	E>K		No	ClinGen Ensembl
rs1316812594 CA345350308	552	V>A		No	ClinGen gnomAD
CA1472161 rs756878800	553	T>M		No	ClinGen ExAC TOPMed gnomAD
CA345350293 rs1367473871	555	S>P		No	ClinGen TOPMed gnomAD
CA1472158 rs547940210	556	N>D		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs547940210 CA345350288	556	N>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1440971975 CA345350284	556	N>K		No	ClinGen TOPMed
CA1472157 rs145749709	556	N>S		No	ClinGen 1000Genomes ExAC gnomAD
rs140131566 CA1472156	557	L>F		No	ClinGen ESP ExAC TOPMed gnomAD
CA345350277 rs1337353679	558	L>M		No	ClinGen gnomAD
rs1337353679 CA345350276	558	L>V		No	ClinGen gnomAD
rs1453439911 CA345350249	562	Q>E		No	ClinGen gnomAD
CA1472153 rs772707877	562	Q>H		No	ClinGen ExAC gnomAD
CA1472154 rs748860670	562	Q>R		No	ClinGen ExAC gnomAD
CA1472152 rs143731772	564	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA345350218 rs1572049062	567	S>T		No	ClinGen Ensembl
CA345350200 rs1386061997	569	N>S		No	ClinGen TOPMed
CA1472151 rs56242514	570	G>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA345350187 rs1164518130	571	E>G		No	ClinGen gnomAD
rs749324042 CA1472125 COSM161478	574	E>K	breast [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA39700323 rs755382938	575	V>L		No	ClinGen gnomAD
CA345350027 COSM3977229 rs1558189046	578	I>V	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated Ensembl NCI-TCGA
rs1387819319 CA345350008	579	A>V		No	ClinGen TOPMed
rs60920266 CA1472123	580	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	581	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345349988 rs1388367604	582	I>V		No	ClinGen TOPMed
rs1300716566 CA345349973	584	I>V		No	ClinGen gnomAD
TCGA novel	586	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs368628396 CA1472119	588	I>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs766208942 CA1472118	594	Q>P		No	ClinGen ExAC TOPMed gnomAD
CA1472117 rs766208942	594	Q>R		No	ClinGen ExAC TOPMed gnomAD
rs763010853 CA1472116	597	N>D		No	ClinGen ExAC TOPMed gnomAD
CA1472115 rs542127174	598	Q>R		No	ClinGen 1000Genomes ExAC gnomAD
rs764744234 CA1472114	599	V>L		No	ClinGen ExAC
rs1052896128 CA39700274	600	V>A		No	ClinGen TOPMed
CA1472113 rs574745592	600	V>I		No	ClinGen 1000Genomes ExAC gnomAD
rs1037928329 CA39700263	601	V>I		No	ClinGen TOPMed gnomAD
rs759970054 CA1472110	602	C>S		No	ClinGen ExAC TOPMed gnomAD
CA345349851 rs1286114741	602	C>Y		No	ClinGen gnomAD
CA39700254 rs943902812	606	F>Y		No	ClinGen Ensembl
rs2794763 CA345349821	607	M>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs2794763 CA1472109 VAR_049330	607	M>V		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA345349806 rs1255429441	609	I>V		No	ClinGen gnomAD
rs549697437 CA1472108	610	N>S		No	ClinGen 1000Genomes ExAC gnomAD
CA345349785 rs1553284527	612	D>H		No	ClinGen Ensembl
CA1472106 rs1553284527	612	D>N		No	ClinGen Ensembl
rs1483791970 CA345349781	612	D>V		No	ClinGen TOPMed
CA39700244 rs1049503654	614	T>A		No	ClinGen TOPMed
rs141140258 CA1472105	614	T>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs769876017 CA1472103	615	E>Q		No	ClinGen ExAC gnomAD
rs1402132704 CA345349740	618	E>D		No	ClinGen TOPMed gnomAD
rs188429321 CA1472102	618	E>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA345349735 rs1311564088	619	M>K		No	ClinGen TOPMed
CA345349734 rs1311564088	619	M>T		No	ClinGen TOPMed
rs781365715 CA1472101	620	K>R		No	ClinGen ExAC TOPMed gnomAD
CA345349721 rs1572048448	621	I>V		No	ClinGen Ensembl
rs1429530921 CA345349715	622	A>T		No	ClinGen gnomAD
CA345349703 rs1371406799	623	I>M		No	ClinGen TOPMed
CA1472099 rs138177334	627	K>E		No	ClinGen ESP ExAC TOPMed gnomAD
rs1243566907 CA345349679	627	K>T		No	ClinGen gnomAD
rs758139252 CA1472097	631	C>G		No	ClinGen ExAC gnomAD
CA1472096 rs750336767	632	S>C		No	ClinGen ExAC gnomAD
CA345349644 rs750336767	632	S>F		No	ClinGen ExAC gnomAD
rs936496104 CA39700225	634	H>Q		No	ClinGen TOPMed gnomAD
rs1201819590 CA345349635	634	H>Y		No	ClinGen TOPMed gnomAD
CA1472095 rs765128251	635	P>L		No	ClinGen ExAC gnomAD
TCGA novel	635	P>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs765143633 CA39700210	641	E>K		No	ClinGen TOPMed gnomAD
rs555144272 CA39700194	642	E>*		No	ClinGen Ensembl
rs939728257 CA39700006	643	A>V		No	ClinGen Ensembl
rs753834969 CA1472073	647	V>A		No	ClinGen ExAC gnomAD
TCGA novel	648	I>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345349404 rs1165241484	648	I>V		No	ClinGen TOPMed gnomAD
CA1472072 rs370681768	649	K>R		No	ClinGen ESP ExAC gnomAD
rs755711214 CA1472071	651	T>P		No	ClinGen ExAC
rs1350872342 CA345349331	653	P>L		No	ClinGen TOPMed
CA1472069 rs767113628	658	G>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA345349258 rs1205440856	659	V>A		No	ClinGen gnomAD
rs763351260 CA1472068	660	A>T		No	ClinGen ExAC gnomAD
rs1228473777 CA345349242	661	N>D		No	ClinGen TOPMed
rs1228473777 CA345349243	661	N>H		No	ClinGen TOPMed
CA1472067 rs773502970	664	M>L		No	ClinGen ExAC gnomAD
rs773502970 CA345349197	664	M>V		No	ClinGen ExAC gnomAD
rs765724810 CA1472066	665	I>F		No	ClinGen ExAC gnomAD
rs1221551348 CA345349157	667	L>M		No	ClinGen TOPMed gnomAD
rs560970846 CA39699946	669	A>T		No	ClinGen Ensembl
TCGA novel	670	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1472064 rs527740697	671	N>S		No	ClinGen 1000Genomes ExAC TOPMed
rs1374812250 CA345349069	673	N>S		No	ClinGen gnomAD
rs747100163 CA1472062	676	D>A		No	ClinGen ExAC
rs1488980962 CA345349019	677	P>T		No	ClinGen gnomAD
CA1472058 CA1472059 rs778787258	680	M>I		No	ClinGen ExAC gnomAD
rs376159886 CA1472061	680	M>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1472060 rs376159886	680	M>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs41308194 RCV000887955 CA1472056	681	L>V		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs777890759 CA1472055	682	K>E		No	ClinGen ExAC gnomAD
rs980188884 CA39699878	682	K>N		No	ClinGen Ensembl
TCGA novel	685	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1572047798 CA345348812	686	D>N		No	ClinGen Ensembl
CA345348786 rs1006456	687	L>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	687	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1261387910 CA345348779	688	I>R		No	ClinGen TOPMed gnomAD
CA345348775 rs1185152791	689	S>G		No	ClinGen TOPMed gnomAD
rs1487127179 CA345348769	689	S>T		No	ClinGen gnomAD
rs111453499 CA1472029	690	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA1472028 rs111453499	690	V>M		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	691	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA39699470 rs956931200	692	E>G		No	ClinGen TOPMed
CA345348744 rs1459555716	693	E>G		No	ClinGen gnomAD
rs1264495958 CA345348738	694	E>*		No	ClinGen TOPMed gnomAD
rs1223680249 CA345348736	694	E>A		No	ClinGen TOPMed gnomAD
CA345348733 rs1306579157	694	E>D		No	ClinGen gnomAD
rs886750644 CA39699464	695	S>P		No	ClinGen Ensembl
CA1472023 rs767450820	697	N>K		No	ClinGen ExAC gnomAD
rs200590400 CA1472024	697	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA345348712 rs1250227751	698	L>V		No	ClinGen TOPMed
CA1472022 rs759695973	699	K>E		No	ClinGen ExAC gnomAD
CA1472021 rs774685885	699	K>R		No	ClinGen ExAC gnomAD
CA345348701 rs1466691963	700	Q>E		No	ClinGen gnomAD
rs771325790 CA1472020	702	V>I		No	ClinGen ExAC gnomAD
CA1472018 rs374353213 COSM906051	703	T>M	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
rs374353213 CA1472019	703	T>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA1472016 rs747976958	705	H>R		No	ClinGen ExAC gnomAD
CA345348655 rs1012278529	707	I>F		No	ClinGen TOPMed gnomAD
CA39699374 rs1012278529	707	I>V		No	ClinGen TOPMed gnomAD
rs781210802 CA1472015	708	L>V		No	ClinGen ExAC gnomAD
CA345348645 rs1391030530	709	S>P		No	ClinGen TOPMed
CA345348636 rs1244388471	710	V>A		No	ClinGen gnomAD
rs746559932 CA1472013	712	V>I		No	ClinGen ExAC gnomAD
rs376992643 CA1472011	713	S>C		No	ClinGen ESP ExAC gnomAD
rs199564595 CA1472010	714	C>Y		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1472007 rs756526983	717	S>Y		No	ClinGen ExAC gnomAD
COSM106750 CA39699313 rs145377606	720	E>K	skin [Cosmic]	No	ClinGen cosmic curated Ensembl
rs1396740219 CA345348567	721	T>N		No	ClinGen TOPMed gnomAD
CA345348560 rs1296713557	722	H>R		No	ClinGen gnomAD
rs202037998 CA1472004	723	F>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs766701060 CA1472002	724	P>L		No	ClinGen ExAC gnomAD
rs150874819 CA1472001	725	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA345348526 rs1418054710	727	I>M		No	ClinGen gnomAD
CA1471999 rs140350692 RCV000906233	727	I>T		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs761698721 CA1471998	728	R>G		No	ClinGen ExAC gnomAD
rs1178534317 CA345348521	728	R>S		No	ClinGen gnomAD
rs878979005 CA39699285	729	V>I		No	ClinGen Ensembl
CA1471997 rs373793253	730	F>L		No	ClinGen ESP ExAC gnomAD
CA39699284 rs975367128	730	F>L		No	ClinGen Ensembl
CA345348500 rs1220051176	732	L>M		No	ClinGen gnomAD
rs1361493176 CA345348497	732	L>S		No	ClinGen gnomAD
rs768685835 CA1471996	734	Q>H		No	ClinGen ExAC gnomAD
rs1245581812 CA345348478	735	K>E		No	ClinGen gnomAD
CA39699277 rs867230417	735	K>N		No	ClinGen Ensembl
CA345348468 rs1335193309	736	K>R		No	ClinGen gnomAD
rs1257881359 CA345348462	737	I>L		No	ClinGen TOPMed gnomAD
TCGA novel	737	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs556876977 CA1471994	738	K>Q		No	ClinGen 1000Genomes ExAC gnomAD
CA1471993 rs137889824	739	K>E		No	ClinGen ESP ExAC TOPMed gnomAD
rs745478013 CA1471991	742	S>I		No	ClinGen ExAC gnomAD
CA1471990 rs141347838	743	V>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs577915974 CA1471989	744	I>F		No	ClinGen 1000Genomes ExAC gnomAD
rs1361485707 CA345348415	744	I>T		No	ClinGen gnomAD
CA345348406 rs1160673123	745	T>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
TCGA novel	745	T>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1472706235 CA345348399	747	V>M		No	ClinGen TOPMed gnomAD
rs895039767 CA39759312	749	I>F		No	ClinGen gnomAD
rs895039767 CA345373147	749	I>V		No	ClinGen gnomAD
rs773856156 CA1471972	754	H>L		No	ClinGen ExAC gnomAD
TCGA novel	754	H>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345373105 rs770677548 COSM1738474	755	I>F	haematopoietic_and_lymphoid_tissue [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA1471970 rs748453232	755	I>M		No	ClinGen ExAC gnomAD
CA1471971 rs770677548	755	I>V		No	ClinGen ExAC gnomAD
rs1465364915 CA345373082	758	M>I		No	ClinGen gnomAD
CA345373086 rs1357754742	758	M>L		No	ClinGen TOPMed
rs781550957 CA1471969	758	M>T		No	ClinGen ExAC gnomAD
CA39759283 rs1000648669	761	R>G		No	ClinGen Ensembl
rs149323115 CA39759269	763	I>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA345373049 rs1289073109	763	I>T		No	ClinGen TOPMed
rs928302063 CA39759257	764	P>S		No	ClinGen TOPMed
rs1275797541 CA345373038	765	V>A		No	ClinGen gnomAD
CA345373026 rs1325163516	767	L>P		No	ClinGen gnomAD
rs1436491259 CA345373023	768	W>R		No	ClinGen gnomAD
rs933088417 CA39759249	768	W>S		No	ClinGen TOPMed
CA1471963 rs778988401	770	H>D		No	ClinGen ExAC gnomAD
CA345373005 rs1298971377	770	H>R		No	ClinGen TOPMed
rs145047352 CA1471961	771	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs145047352 CA345372999	771	Y>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs553495718 CA1471962	771	Y>H		No	ClinGen 1000Genomes ExAC gnomAD
CA1471960 rs763828193	774	E>G		No	ClinGen ExAC gnomAD
rs752604734 CA1471958	776	N>K		No	ClinGen ExAC gnomAD
rs1374608694 CA345372961	777	S>G		No	ClinGen gnomAD
CA345372953 rs1261524292	778	T>A		No	ClinGen TOPMed
CA345372949 rs1489314500	778	T>I		No	ClinGen TOPMed
CA345372947 rs1214468369	779	Q>E		No	ClinGen TOPMed
TCGA novel	779	Q>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1471956 rs528453790	781	V>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA345372928 rs1558187653	782	A>T		No	ClinGen Ensembl
CA1471954 rs148574750	783	V>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA1471953 rs762603899	785	D>E		No	ClinGen ExAC TOPMed gnomAD
CA1471952 rs200168702	786	S>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA345372895 rs1298179595	787	V>F		No	ClinGen Ensembl
rs145813934 CA1471951	790	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs145813934 CA345372877 CA345372876	790	V>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA1471949 rs780682035	793	L>F		No	ClinGen ExAC TOPMed gnomAD
CA345372851 rs1312276290	794	K>E		No	ClinGen TOPMed gnomAD
CA39759185 rs931431219	795	K>I		No	ClinGen Ensembl
TCGA novel	795	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1471946 rs778995015	796	F>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	796	F>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs746366377 CA1471947	796	F>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs975652070 CA39759154	797	I>T		No	ClinGen TOPMed gnomAD
CA39759170 rs1027247087	797	I>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs757307538 COSM3705655 CA1471945	799	A>V	liver [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA1471944 rs754053380	800	L>P		No	ClinGen ExAC TOPMed gnomAD
rs1181797531 CA345372797	802	A>G		No	ClinGen TOPMed gnomAD
CA39759128 rs200192326	804	K>I		No	ClinGen ExAC TOPMed
CA1471943 rs200192326	804	K>T		No	ClinGen ExAC TOPMed
rs755885940 CA1471942	805	S>C		No	ClinGen ExAC TOPMed gnomAD
rs755885940 CA39759106	805	S>Y		No	ClinGen ExAC TOPMed gnomAD
CA1471940 rs767441332	806	F>S		No	ClinGen ExAC gnomAD
CA345372767 rs1206406771	807	P>L		No	ClinGen gnomAD
rs1277198658 CA345372770	807	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs749461466 CA1471920	811	I>L		No	ClinGen ExAC gnomAD
CA345372730 rs751470101	811	I>R		No	ClinGen ExAC gnomAD
CA1471919 rs751470101	811	I>T		No	ClinGen ExAC gnomAD
rs749461466 CA39758900	811	I>V		No	ClinGen ExAC gnomAD
rs757902623 CA345372728 CA1471917	812	W>R		No	ClinGen ExAC gnomAD
rs1437031937 CA345372717	813	W>*		No	ClinGen gnomAD
rs1397930270 CA345372720	813	W>R		No	ClinGen TOPMed
rs200554151 CA1471915	824	D>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA345372636 rs1317692793	824	D>H		No	ClinGen TOPMed gnomAD
rs761501312 CA1471914	825	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA1471913 rs776445716	827	H>Q		No	ClinGen ExAC gnomAD
rs1480235985 CA345372603	829	L>V		No	ClinGen gnomAD
rs1282543751 CA345372596	830	I>F		No	ClinGen TOPMed
CA1471911 rs759860055	830	I>T		No	ClinGen ExAC TOPMed gnomAD
rs774903242 CA1471910	831	G>R		No	ClinGen ExAC gnomAD
CA1471909 rs370893770	833	F>L		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	834	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs368009730 CA1471908	835	M>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs1230488285 CA345372565	835	M>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA345372566 rs1230488285	835	M>V		No	ClinGen TOPMed
rs1465821964 CA345372550	837	L>F		No	ClinGen gnomAD
rs147175308 CA1471907	838	N>D		No	ClinGen ESP ExAC gnomAD
CA1471906 rs374427656	838	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA1471905 rs748315794	839	G>S		No	ClinGen ExAC gnomAD
rs781420901 CA1471904	840	A>V		No	ClinGen ExAC gnomAD
CA1471902 rs746827890	841	D>G		No	ClinGen ExAC TOPMed gnomAD
CA1471903 rs370263527	841	D>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs1321316442 CA345372512	843	V>A		No	ClinGen gnomAD
rs139503389 CA39758797	844	H>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs1322112633 CA345372508	844	H>R		No	ClinGen TOPMed gnomAD
rs139503389 CA1471900	844	H>Y		No	ClinGen ESP ExAC TOPMed gnomAD
CA345372471 rs1553284088	849	M>I		No	ClinGen Ensembl
rs1572045999 CA345372449	852	F>L		No	ClinGen Ensembl
rs1357712835 CA345372453	852	F>L		No	ClinGen gnomAD
CA1471899 rs750389344	853	I>M		No	ClinGen ExAC gnomAD
CA345372416 rs1412121353	855	V>G		No	ClinGen gnomAD
rs1306554368 CA345372419	855	V>L		No	ClinGen gnomAD
CA345372398 rs1214250136	858	E>G		No	ClinGen TOPMed
rs1163462597 CA345372370	862	Q>*		No	ClinGen gnomAD
rs1260565749 CA345372356	864	F>L		No	ClinGen TOPMed
rs752410401 CA1471868	864	F>L		No	ClinGen ExAC gnomAD
CA39757743 rs943144674	865	K>T		No	ClinGen TOPMed gnomAD
CA1471867 rs766599773	866	F>L		No	ClinGen ExAC gnomAD
rs766599773 CA345372342	866	F>V		No	ClinGen ExAC gnomAD
rs763334492 CA1471866	869	V>I		No	ClinGen ExAC gnomAD
rs765778239 CA1471864	870	L>F		No	ClinGen ExAC
rs369564820 CA1471863	872	T>S		No	ClinGen ESP ExAC gnomAD
rs776639028 CA1471862	873	Y>C		No	ClinGen ExAC gnomAD
rs760750212 CA1471860	880	P>L		No	ClinGen ExAC TOPMed gnomAD
CA1471861 rs201241450	880	P>S		No	ClinGen ExAC TOPMed gnomAD
rs1245697995 CA345372245	881	L>V		No	ClinGen TOPMed gnomAD
CA1471858 rs147383856	884	S>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1471856 rs375206460	885	V>M		No	ClinGen ESP ExAC gnomAD
CA39757672 rs994861000	886	K>E		No	ClinGen Ensembl
CA1471855 rs771062009	887	T>R		No	ClinGen ExAC gnomAD
rs1393602833 CA345372199	888	V>L		No	ClinGen gnomAD
CA345372189 rs1417304159	890	Q>E		No	ClinGen TOPMed
CA345372157 rs1350260822	894	L>R		No	ClinGen TOPMed
rs1428266533 CA345372116	900	M>I		No	ClinGen gnomAD
CA1471851 rs752248066	900	M>V		No	ClinGen ExAC TOPMed gnomAD
CA345372110 rs1196551815	901	L>P		No	ClinGen gnomAD
TCGA novel	903	S>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA39757630 rs767087161	903	S>C		No	ClinGen Ensembl
rs750843509 CA1471848	907	Q>R		No	ClinGen ExAC gnomAD
CA345372063 rs1485562499	908	C>F		No	ClinGen gnomAD
rs1558186768 CA345372042	911	Q>E		No	ClinGen Ensembl
rs765726863 CA1471847	911	Q>P		No	ClinGen ExAC gnomAD
CA345372031 rs1330151312	913	A>T		No	ClinGen gnomAD
CA345372025 rs1283040331	914	S>P		No	ClinGen gnomAD
CA1471845 rs752020178	915	I>L		No	ClinGen ExAC gnomAD
CA39757616 rs752020178	915	I>V		No	ClinGen ExAC gnomAD
CA345372011 rs1333314953	916	S>C		No	ClinGen TOPMed gnomAD
rs940469809 CA39757608	917	S>P		No	ClinGen TOPMed
CA1471844 rs764041923	917	S>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1415826685 CA345371966	922	S>Y		No	ClinGen gnomAD
CA345371939 rs1572042657	926	N>T		No	ClinGen Ensembl
rs150389618 CA1471824	929	S>N		No	ClinGen ESP ExAC TOPMed gnomAD
CA345371913 rs1294243318	930	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs756136936 CA1471822	930	P>S		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	931	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs374645333 CA1471820	931	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1471819 rs759778339	932	K>E		No	ClinGen ExAC TOPMed gnomAD
CA345371884 rs1237006144	935	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1185603876 CA345371882	935	R>H		No	ClinGen gnomAD
TCGA novel	937	A>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1471818 rs766233566 COSM464191 CA1471817	940	Q>H	Variant assessed as Somatic; 0.0 impact. kidney [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA39753735 rs1040389283	940	Q>L		No	ClinGen TOPMed
rs1007156255 CA39753690	944	A>G		No	ClinGen TOPMed
CA1471813 rs747606599	945	L>V		No	ClinGen ExAC gnomAD
CA1471811 rs111564783 RCV000953017	946	S>G		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA345371812 rs1354957777	946	S>R		No	ClinGen gnomAD
rs779722182 CA1471809	947	G>E		No	ClinGen ExAC gnomAD
rs372365051 CA1471810	947	G>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA39753656 rs761816782	949	A>T		No	ClinGen Ensembl
rs150392772 CA1471805 COSM1340361	951	P>L	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
rs150392772 CA1471806	951	P>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1471807 rs749721725	951	P>S		No	ClinGen ExAC gnomAD
CA1471803 rs368605325	953	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs1169102935 CA345371777	953	Y>H		No	ClinGen gnomAD
CA345371769 rs1473893386	954	L>Q		No	ClinGen gnomAD
CA1471801 rs766753791	955	I>L		No	ClinGen ExAC TOPMed gnomAD
rs766753791 CA1471800	955	I>V		No	ClinGen ExAC TOPMed gnomAD
CA39753593 rs1055044456	956	I>M		No	ClinGen Ensembl
CA39753599 rs896595716	956	I>T		No	ClinGen gnomAD
CA345371760 rs1181882448	956	I>V		No	ClinGen TOPMed gnomAD
rs16833953 VAR_049331 CA1471799	957	D>G		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA345371749 rs144454146	958	H>N		No	ClinGen ESP ExAC TOPMed gnomAD
CA345371747 rs1409736793	958	H>R		No	ClinGen gnomAD
CA1471798 COSM226495 rs144454146	958	H>Y	skin [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA1471797 rs764943663	959	L>W		No	ClinGen ExAC gnomAD
rs761751615 CA1471796	961	S>T		No	ClinGen ExAC gnomAD
CA345371723 rs1229579517	962	K>E		No	ClinGen gnomAD
CA345371706 rs1221082885	964	E>G		No	ClinGen TOPMed
CA39753523 rs925192148	965	E>D		No	ClinGen Ensembl
CA1471794 rs768114304	965	E>K		No	ClinGen ExAC gnomAD
CA345371694 rs1558185030	966	I>F		No	ClinGen Ensembl
rs760228304 CA1471792	966	I>M		No	ClinGen ExAC gnomAD
rs1352026682 CA345371688	967	T>P		No	ClinGen gnomAD
rs375239299 CA1471791	968	S>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs150596810 CA1471789	969	D>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA345371679 rs141424510	969	D>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1471790 rs141424510	969	D>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA345371673 rs1401650215	970	A>T		No	ClinGen gnomAD
CA345371668 rs1321635502	970	A>V		No	ClinGen gnomAD
CA1471788 rs200043693	972	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs770080121 CA1471787	974	I>S		No	ClinGen ExAC TOPMed gnomAD
CA345371636 rs1158652841	975	Q>H		No	ClinGen TOPMed gnomAD
CA345371600 rs1572042328	979	T>A		No	ClinGen Ensembl
rs1310174969 CA345371564	984	L>I		No	ClinGen gnomAD
rs781760286 CA1471767	985	Q>E		No	ClinGen ExAC
rs1280477369 CA345371554	985	Q>H		No	ClinGen gnomAD
TCGA novel	985	Q>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1471766 rs769350794	988	K>E		No	ClinGen ExAC TOPMed gnomAD
rs1296928197 CA345371522	990	L>M		No	ClinGen gnomAD
CA345371501 rs1367472177	993	H>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs780122575 CA1471764	999	T>S		No	ClinGen ExAC gnomAD
rs1178758037 CA345371434 COSM1601952	1002	N>S	liver [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
rs758428014 CA1471763	1004	L>F		No	ClinGen ExAC gnomAD
CA1471762 rs750617675	1004	L>P		No	ClinGen ExAC gnomAD
rs779043626 CA1471761	1005	S>I		No	ClinGen ExAC TOPMed gnomAD
rs779043626 CA39753145	1005	S>T		No	ClinGen ExAC TOPMed gnomAD
rs1245609152 CA345371410	1006	C>Y		No	ClinGen TOPMed
CA345371390 rs1201810877	1009	S>G		No	ClinGen gnomAD
rs753700598 CA345371374	1011	P>A		No	ClinGen ExAC TOPMed gnomAD
CA1471759 rs753700598	1011	P>S		No	ClinGen ExAC TOPMed gnomAD
rs1482078598 CA345371369	1012	S>P		No	ClinGen gnomAD
rs1210607875 CA345371328	1017	D>E		No	ClinGen TOPMed gnomAD
TCGA novel	1017	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345371330 rs1345350045	1017	D>V		No	ClinGen gnomAD
rs760549674 CA1471757	1018	L>W		No	ClinGen ExAC gnomAD
CA1471756 rs752601785	1019	M>V		No	ClinGen ExAC TOPMed gnomAD
CA345371312 rs1558184818	1020	K>E		No	ClinGen Ensembl
CA345371300 rs1228095127	1021	V>A		No	ClinGen gnomAD
rs1230563705 CA345371305	1021	V>I		No	ClinGen gnomAD
rs1344332024 CA345371296	1022	L>H		No	ClinGen gnomAD
rs138072030 CA1471755	1026	N>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs202082960 CA39753076	1026	N>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs202082960 CA1471754	1026	N>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1471752 rs766001824	1027	G>S		No	ClinGen ExAC TOPMed gnomAD
rs1419565952 CA345371226	1031	L>I		No	ClinGen gnomAD
rs1208009274 CA345371195	1036	P>A		No	ClinGen gnomAD
CA345371192 rs200561440	1036	P>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1471730 rs200561440	1036	P>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs776042549 CA1471727	1037	M>I		No	ClinGen ExAC gnomAD
rs760985649 CA1471728	1037	M>T		No	ClinGen ExAC TOPMed gnomAD
rs764511876 CA1471729	1037	M>V		No	ClinGen ExAC TOPMed gnomAD
CA345371180 rs1325834649	1038	A>V		No	ClinGen TOPMed
rs772521784 CA1471726	1039	E>K		No	ClinGen ExAC TOPMed gnomAD
CA1471725 rs116166233	1040	Q>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA345371168 rs116166233	1040	Q>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1342642340 CA345371161	1041	L>R		No	ClinGen TOPMed
TCGA novel	1043	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345371145 rs1209817596	1044	K>*		No	ClinGen TOPMed
rs771023803 CA1471723	1044	K>N		No	ClinGen ExAC gnomAD
CA1471722 rs148105576	1046	Q>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA39751880 rs894632494	1046	Q>R		No	ClinGen TOPMed gnomAD
rs1218967730 CA345371126	1047	K>E		No	ClinGen TOPMed
CA39751876 rs867224313	1048	E>D		No	ClinGen Ensembl
rs1558184403 CA345371119	1048	E>K		No	ClinGen Ensembl
CA1471721 rs778012930	1049	P>S		No	ClinGen ExAC gnomAD
rs781181903 CA1471718	1050	T>A		No	ClinGen ExAC TOPMed gnomAD
CA39751848 rs959869052	1050	T>I		No	ClinGen gnomAD
rs1379828744 CA345371093	1052	V>A		No	ClinGen TOPMed
rs1383652725 CA345371074	1055	D>G		No	ClinGen gnomAD
CA39751840 rs919467404	1056	E>K		No	ClinGen TOPMed gnomAD
CA1471717 rs754802213	1057	A>P		No	ClinGen ExAC gnomAD
CA39751829 rs752591205	1058	M>V		No	ClinGen Ensembl
CA345371036 rs1380599136	1061	H>R		No	ClinGen TOPMed
CA1471716 rs751525354	1061	H>Y		No	ClinGen ExAC gnomAD
rs1266419649 CA345371026	1063	T>A		No	ClinGen gnomAD
CA39751823 rs868743217	1063	T>I		No	ClinGen gnomAD
TCGA novel	1065	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1255787329 CA345371006	1066	K>R		No	ClinGen gnomAD
CA345370998 rs1314537948	1067	Y>C		No	ClinGen gnomAD
rs905633436 CA39751818	1068	N>S		No	ClinGen gnomAD
rs370869084 CA1471713	1076	N>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs765031157 CA1471712	1076	N>K		No	ClinGen ExAC gnomAD
rs370869084 CA39751816	1076	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs761095912 CA1471711	1077	E>K		No	ClinGen ExAC gnomAD
CA39751788 rs909329329	1078	D>G		No	ClinGen TOPMed gnomAD
COSM354856 CA1471709 rs767937308	1079	P>L	lung [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs1167908231 CA345370919	1079	P>T		No	ClinGen gnomAD
CA39751771 rs894021340	1080	K>R		No	ClinGen Ensembl
rs199616842 CA345370890	1083	D>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1195526194 CA345370895	1083	D>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA345370891 rs1447861094	1083	D>V		No	ClinGen gnomAD
rs763065743 CA1471705	1084	I>M		No	ClinGen ExAC gnomAD
CA1471706 rs377284390	1084	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA1471704 rs773405671	1086	I>V		No	ClinGen ExAC gnomAD
CA1471703 rs770073279	1090	H>R		No	ClinGen ExAC TOPMed gnomAD
CA345370849 rs1354744843	1090	H>Y		No	ClinGen TOPMed
CA39751697 rs956625027	1091	T>R		No	ClinGen TOPMed
rs748410988 CA1471702	1091	T>S		No	ClinGen ExAC gnomAD
CA39751674 rs1051964000	1092	T>A		No	ClinGen TOPMed gnomAD
CA345370834 rs1339572617	1092	T>I		No	ClinGen TOPMed gnomAD
CA345370835 rs1339572617	1092	T>R		No	ClinGen TOPMed gnomAD
rs1331916027 CA345370832	1093	K>E		No	ClinGen TOPMed gnomAD
rs1193465458 CA345370827	1093	K>N		No	ClinGen TOPMed
CA345370817 rs1375870736	1095	L>F		No	ClinGen gnomAD
CA1471698 rs780182886	1096	Y>C		No	ClinGen ExAC gnomAD
CA1471699 rs746883150	1096	Y>H		No	ClinGen ExAC gnomAD
COSM355350 CA1471696 rs139477120	1097	A>T	lung [Cosmic]	No	ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD
CA1471695 rs778570394 COSM1185799	1097	A>V	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	1098	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs753548904 CA1471693	1098	G>E		No	ClinGen ExAC TOPMed gnomAD
CA39751597 rs767731232	1101	T>A		No	ClinGen ExAC TOPMed gnomAD
CA1471692 rs767731232	1101	T>P		No	ClinGen ExAC TOPMed gnomAD
rs372897306 CA345370776	1102	I>F		No	ClinGen ESP ExAC TOPMed gnomAD
CA1471690 rs79225714	1102	I>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs372897306 CA1471691	1102	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs369436014 CA1471689	1103	Q>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA1471688 rs763012371	1105	T>A		No	ClinGen ExAC gnomAD
CA345370756 rs1355068308	1105	T>I		No	ClinGen gnomAD
rs773213234 CA1471687	1106	A>T		No	ClinGen ExAC gnomAD
CA1471684 rs377405226	1108	E>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1471683 rs377405226	1108	E>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs377405226 CA1471685	1108	E>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs777283123 CA1471658	1110	I>M		No	ClinGen ExAC gnomAD
COSM533537 CA345370716 rs1246982024	1110	I>V	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA gnomAD
CA1471657 rs755720751	1111	T>I		No	ClinGen ExAC TOPMed gnomAD
CA345370701 rs1572041172	1112	K>N		No	ClinGen Ensembl
rs1040417521 CA39751091	1112	K>Q		No	ClinGen TOPMed gnomAD
rs928589629 CA39751089	1113	P>R		No	ClinGen Ensembl
rs1301690036 CA345370699	1113	P>T		No	ClinGen TOPMed
rs979922845 CA39751087	1115	F>C		No	ClinGen TOPMed
CA345370682 rs979922845	1115	F>S		No	ClinGen TOPMed
CA1471656 rs747816359	1116	A>P		No	ClinGen ExAC gnomAD
rs1240383488 CA345370677	1116	A>V		No	ClinGen TOPMed
rs780352052 CA39751058	1117	A>D		No	ClinGen ExAC TOPMed gnomAD
rs780352052 CA1471655	1117	A>V		No	ClinGen ExAC TOPMed gnomAD
rs1443259829 CA345370669	1118	I>V		No	ClinGen gnomAD
CA1471653 rs750900693	1119	S>T		No	ClinGen ExAC TOPMed gnomAD
rs1239661224 CA345370653	1120	D>V		No	ClinGen Ensembl
rs765823873 CA1471652	1121	E>G		No	ClinGen ExAC gnomAD
TCGA novel	1121	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345370638 rs1247284014	1122	K>N		No	ClinGen TOPMed
CA39751048 rs576961723	1122	K>T		No	ClinGen 1000Genomes
rs4659683 CA345370633	1123	V>D		No	ClinGen gnomAD
rs4659683 CA39751038	1123	V>G		No	ClinGen gnomAD
CA39751029 rs935189490	1124	Q>E		No	ClinGen TOPMed gnomAD
CA345370612 rs1191564420	1126	K>R		No	ClinGen TOPMed
TCGA novel	1127	L>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1471648 rs376304118	1132	F>L		No	ClinGen ESP ExAC gnomAD
CA39750979 rs748718984	1132	F>S		No	ClinGen Ensembl
rs760930540 CA39750961	1134	L>F		No	ClinGen ExAC TOPMed gnomAD
rs1410371050 CA345370550	1135	L>W		No	ClinGen TOPMed
CA1471645 rs767386827	1137	N>S		No	ClinGen ExAC gnomAD
CA1471643 rs558762339	1140	N>Y		No	ClinGen 1000Genomes ExAC gnomAD
CA39750951 rs868631637	1143	C>G		No	ClinGen TOPMed gnomAD
CA39750949 rs954936526	1144	A>S		No	ClinGen Ensembl
CA345370471 rs1351035218	1146	T>I		No	ClinGen TOPMed
CA345370472 rs1351035218	1146	T>S		No	ClinGen TOPMed
rs770963849 CA1471642	1149	S>G		No	ClinGen ExAC TOPMed gnomAD
rs1234936825 CA345370453	1149	S>N		No	ClinGen gnomAD
CA345370438 rs1435073996	1151	F>S		No	ClinGen Ensembl
rs749182752 CA1471641	1152	K>*		No	ClinGen ExAC gnomAD
rs1297033041 CA345370422	1153	G>V		No	ClinGen gnomAD
CA345370408 rs1461819063	1154	I>V		No	ClinGen TOPMed
CA1471616 rs781305437	1156	V>I		No	ClinGen ExAC TOPMed gnomAD
rs1045981863 CA39749550	1157	N>H		No	ClinGen Ensembl
rs779288098 COSM224185 CA1471615	1158	A>T	skin [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs771230939 CA1471614	1158	A>V		No	ClinGen ExAC gnomAD
CA39749522 rs749028568	1160	Q>R		No	ClinGen Ensembl
CA345370356 rs374984885	1162	R>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA1471612 rs374984885	1162	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA345370349 rs1221098148	1163	I>M		No	ClinGen gnomAD
CA1471610 rs756246368	1164	E>G		No	ClinGen ExAC gnomAD
rs1275406568 CA345370327	1167	P>S		No	ClinGen gnomAD
CA345370317 rs1234338330	1168	P>L		No	ClinGen gnomAD
CA345370320 rs1287081321	1168	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA1471609 rs752889526	1170	K>E		No	ClinGen ExAC gnomAD
CA345370284 rs1393651493	1173	P>L		No	ClinGen TOPMed gnomAD
rs916070176 CA39749468	1174	L>S		No	ClinGen Ensembl
CA1471608 rs781421873	1180	K>N		No	ClinGen ExAC gnomAD
CA345370219 rs1487687476	1183	Q>E		No	ClinGen TOPMed
COSM1185798 rs755166255 CA1471607	1185	M>I	lung [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
rs1208895698 CA345370204	1185	M>V		No	ClinGen TOPMed
CA345370196 rs1165220462	1186	Q>K		No	ClinGen gnomAD
rs751755305 CA1471606	1187	Q>P		No	ClinGen ExAC TOPMed gnomAD
CA1471582 rs765021255	1191	Q>E		No	ClinGen ExAC gnomAD
CA345370135 rs1349339113	1192	D>E		No	ClinGen gnomAD
rs753802952 CA1471580	1192	D>N		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1194	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1303576876 CA345370116	1195	S>C		No	ClinGen gnomAD
TCGA novel	1195	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345370104 rs1223856843	1197	Q>R		No	ClinGen gnomAD
CA345370093 rs149288116	1198	E>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs139560097 CA1471577	1199	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1471576 rs767138512	1200	G>E		No	ClinGen ExAC TOPMed gnomAD
rs1286359454 CA345370087	1200	G>R		No	ClinGen gnomAD
CA39749150 rs527787716	1204	W>C		No	ClinGen TOPMed gnomAD
CA345370044 rs1273391426	1206	R>K		No	ClinGen TOPMed
CA345370036 rs1401272200	1207	V>A		No	ClinGen gnomAD
rs1436520893 CA345370026	1209	L>V		No	ClinGen gnomAD
rs1347977862 CA345370020	1210	I>V		No	ClinGen TOPMed
rs1301811097 CA345370014	1211	L>M		No	ClinGen gnomAD
TCGA novel	1213	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	1219	K>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1407754933 CA345369957	1219	K>Q		No	ClinGen gnomAD
CA39749139 rs58165825	1221	R>K		No	ClinGen Ensembl
CA345369913 rs1475194768	1225	I>L		No	ClinGen gnomAD
rs1429415157 CA345369901	1227	V>M		No	ClinGen gnomAD
rs777322505 CA1471571	1228	P>S		No	ClinGen ExAC gnomAD
CA1471570 rs768761367	1229	T>A		No	ClinGen ExAC TOPMed gnomAD
rs768761367 CA345369890	1229	T>P		No	ClinGen ExAC TOPMed gnomAD
CA39749098 rs894760080	1230	L>F		No	ClinGen gnomAD
CA345369883 rs1280384668	1230	L>H		No	ClinGen gnomAD
rs747120147 CA1471569	1232	N>K		No	ClinGen ExAC gnomAD
rs1336910497 CA345369864	1233	L>V		No	ClinGen gnomAD
rs866586055 CA39748274	1237	C>S		No	ClinGen Ensembl
rs772216623 CA345369814	1239	E>K		No	ClinGen ExAC gnomAD
CA1471549 rs772216623	1239	E>Q		No	ClinGen ExAC gnomAD
CA345369806 rs1334038526	1240	P>A		No	ClinGen gnomAD
rs1558183198 CA345369804	1240	P>H		No	ClinGen Ensembl
CA345369807 rs1334038526	1240	P>T		No	ClinGen gnomAD
rs887404006 TCGA novel CA39748260	1241	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA ClinGen TOPMed
TCGA novel	1242	P>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs968923678 CA39748259	1242	P>S		No	ClinGen TOPMed gnomAD
TCGA novel	1244	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345369778 rs1317380938	1244	E>G		No	ClinGen gnomAD
CA1471547 rs779154192	1246	G>R		No	ClinGen ExAC gnomAD
rs370088862 CA1471546	1247	N>D		No	ClinGen ESP ExAC TOPMed gnomAD
CA345369757 rs1311925045	1247	N>S		No	ClinGen gnomAD
rs375679830 CA1471544	1248	M>T		No	ClinGen ESP ExAC gnomAD
rs749146563 CA1471545	1248	M>V		No	ClinGen ExAC gnomAD
CA1471543 rs199851350	1250	Y>H		No	ClinGen ExAC gnomAD
CA39748243 rs898489518	1251	T>I		No	ClinGen TOPMed
CA1471541 rs201619269	1252	K>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA1471540 rs147110509	1253	Q>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA1471538 rs148988733	1257	S>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA345369684 rs1215180884	1258	C>S		No	ClinGen gnomAD
rs1335170397 CA345369673	1260	L>F		No	ClinGen gnomAD
rs762267730 CA1471537	1260	L>R		No	ClinGen ExAC gnomAD
CA345369663 rs1221996855	1261	N>I		No	ClinGen gnomAD
rs1456611031 CA345369649	1263	C>S		No	ClinGen TOPMed
rs76073611 CA1471534	1264	Q>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA345369644 rs1163120858	1264	Q>K		No	ClinGen TOPMed
rs776097501 CA1471533	1266	L>P		No	ClinGen ExAC TOPMed gnomAD
CA1471530 rs774549532	1267	S>F		No	ClinGen ExAC gnomAD
CA1471528 rs201125369	1268	P>A		No	ClinGen ExAC gnomAD
rs1399441530 CA345369618	1268	P>L		No	ClinGen gnomAD
rs201125369 CA1471529	1268	P>S		No	ClinGen ExAC gnomAD
CA345369606 rs1339037781	1270	G>D		No	ClinGen TOPMed
CA39748152 rs913171186	1270	G>S		No	ClinGen TOPMed
CA1471526 rs769658449	1272	K>R		No	ClinGen ExAC TOPMed gnomAD
CA1471525 rs748001309	1273	I>M		No	ClinGen ExAC gnomAD
TCGA novel	1274	P>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs199948161 CA1471524	1274	P>T		No	ClinGen ExAC TOPMed gnomAD
rs768651802 CA1471504	1276	D>G		No	ClinGen ExAC gnomAD
rs551819849 CA1471523	1276	D>N		No	ClinGen 1000Genomes ExAC gnomAD
rs143410468 CA1471503	1277	I>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1471502 rs779663173	1277	I>T		No	ClinGen ExAC TOPMed gnomAD
CA39747890 rs143410468	1277	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs758015784 CA1471501	1278	L>S		No	ClinGen ExAC gnomAD
CA1471499 rs149379590	1279	D>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1471500 rs148676376	1279	D>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs149379590 CA345369541	1279	D>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs756429013 CA1471498	1281	E>G		No	ClinGen ExAC gnomAD
CA39747875 rs995728790	1281	E>Q		No	ClinGen TOPMed
rs201415717 CA1471496	1282	K>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1354165077 CA345369515	1283	F>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
COSM210460 rs755424367 CA1471494	1285	V>M	large_intestine [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA345369483 COSM1194760 rs1558182997	1287	L>F	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated Ensembl NCI-TCGA
CA39747863 rs61730305	1288	I>T		No	ClinGen TOPMed
rs766412670 CA1471492	1291	C>R		No	ClinGen ExAC gnomAD
CA345369445 rs1411365102 COSM3705654	1293	R>C	liver [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
CA1471491 rs763139216	1293	R>H		No	ClinGen ExAC gnomAD
rs773296322 CA1471490	1295	S>L		No	ClinGen ExAC TOPMed gnomAD
CA1471488 rs372421763	1296	E>A		No	ClinGen ESP ExAC TOPMed gnomAD
rs545842963 CA1471487 CA1471486	1297	M>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1471485 rs749994487	1298	P>L		No	ClinGen ExAC TOPMed gnomAD
CA345369415 rs1483585627	1298	P>S		No	ClinGen gnomAD
rs553776325 CA1471483	1303	H>D		No	ClinGen 1000Genomes ExAC gnomAD
rs745448080 CA1471482	1303	H>R		No	ClinGen ExAC TOPMed gnomAD
CA1471480 rs368783856	1306	L>S		No	ClinGen ESP ExAC gnomAD
rs1296015290 CA345369339	1310	T>A		No	ClinGen TOPMed gnomAD
CA345369337 rs1296015290	1310	T>P		No	ClinGen TOPMed gnomAD
rs755373172 CA345369327	1312	A>P		No	ClinGen ExAC gnomAD
rs755373172 CA1471477	1312	A>T		No	ClinGen ExAC gnomAD
CA1471476 rs752036660	1312	A>V		No	ClinGen ExAC gnomAD
rs1054265331 CA39747657	1313	G>E		No	ClinGen TOPMed gnomAD
rs1054265331 CA39747636	1313	G>V		No	ClinGen TOPMed gnomAD
CA345369318 rs1362499111	1314	I>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA1471475 rs144916392	1315	F>L		No	ClinGen 1000Genomes ExAC gnomAD
CA39747623 rs935904378	1316	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs1441553336 CA345369286	1317	D>N		No	ClinGen gnomAD
CA1471454 rs780403528	1321	H>Q		No	ClinGen ExAC TOPMed gnomAD
rs201502489 CA1471455	1321	H>R		No	ClinGen ExAC gnomAD
CA39744981 rs573451380	1322	N>S		No	ClinGen gnomAD
rs201759425 CA39744954	1324	M>I		No	ClinGen gnomAD
CA1471453 rs758886629	1325	S>C		No	ClinGen ExAC TOPMed gnomAD
CA345369226 rs750920062	1326	I>L		No	ClinGen ExAC gnomAD
CA1471451 rs200421108	1326	I>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA1471452 rs750920062	1326	I>V		No	ClinGen ExAC gnomAD
CA345369220 rs1259418348	1327	F>L		No	ClinGen gnomAD
CA1471449 rs754093326	1330	M>I		No	ClinGen ExAC gnomAD
rs900636432 CA39744923	1330	M>T		No	ClinGen Ensembl
rs1422590594 CA345369186	1332	A>T		No	ClinGen TOPMed
rs764470713 CA1471448	1332	A>V		No	ClinGen ExAC gnomAD
rs999354392 CA39744893	1333	N>D		No	ClinGen TOPMed gnomAD
rs150496012 CA345369178	1333	N>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1471447 rs150496012	1333	N>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA345369179 rs150496012	1333	N>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1381398635 CA345369163	1335	M>I		No	ClinGen gnomAD
rs1301566745 CA345369168	1335	M>V		No	ClinGen gnomAD
COSM1209441 rs376322680 CA1471446	1336	R>C	large_intestine [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA345369158 rs1290503088	1336	R>H		No	ClinGen gnomAD
CA345369133 rs1361245989	1340	T>A		No	ClinGen gnomAD
rs774191479 CA1471443	1342	S>G		No	ClinGen ExAC gnomAD
CA345369117 rs1379540237	1342	S>T		No	ClinGen gnomAD
CA1471442 rs770450442	1343	F>V		No	ClinGen ExAC gnomAD
CA345369076 rs1260154485	1348	K>E		No	ClinGen TOPMed gnomAD
CA345369068 rs1399350520	1349	T>A		No	ClinGen TOPMed
TCGA novel	1349	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345369063 rs1395445012	1350	V>M		No	ClinGen TOPMed
rs1196464250 CA345369042	1352	M>I		No	ClinGen gnomAD
CA39744816 rs373053489	1352	M>T		No	ClinGen ESP TOPMed
CA345369017 rs1208032940	1356	A>E		No	ClinGen gnomAD
CA345369022 rs1278961171 COSM906040	1356	A>T	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
CA345369018 rs1208032940	1356	A>V		No	ClinGen gnomAD
rs371203298 CA1471439	1358	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA345368981 rs1304042244	1360	S>C		No	ClinGen TOPMed
CA1471417 rs186277314	1361	D>G		No	ClinGen 1000Genomes ExAC gnomAD
CA1471416 CA345368943 rs111419712	1366	I>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1471413 rs774919716	1366	I>M		No	ClinGen ExAC TOPMed gnomAD
CA1471414 rs115684254	1366	I>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1471415 rs111419712	1366	I>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs551138097 CA345368925	1369	S>A		No	ClinGen TOPMed
rs551138097 CA39739799	1369	S>P		No	ClinGen TOPMed
rs763890383 CA1471412	1372	V>I		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1374	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345368876 rs1558181342	1376	V>L		No	ClinGen Ensembl
CA1471410 rs749835165	1380	I>F		No	ClinGen ExAC gnomAD
rs777960224 CA1471409	1380	I>T		No	ClinGen ExAC gnomAD
rs1181430777 CA345368834	1382	V>G		No	ClinGen gnomAD
rs146444485 CA1471408	1382	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA345368825 rs1401001587	1384	V>M		No	ClinGen TOPMed
CA345368811 rs1319849547	1386	A>T		No	ClinGen TOPMed
CA1471406 rs781325001	1386	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1034480375 CA39739748	1388	P>L		No	ClinGen gnomAD
CA345368800 rs1239577278	1388	P>S		No	ClinGen gnomAD
rs143307751 CA345368790	1389	H>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1471401 rs750396656	1390	V>I	Variant assessed as Somatic; 4.619e-05 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs761362908 CA1471399	1391	P>L		No	ClinGen ExAC gnomAD
rs142597852 CA1471400	1391	P>T		No	ClinGen ESP ExAC TOPMed gnomAD
COSM210459 rs1447872740 CA345368754	1395	R>C	large_intestine [Cosmic]	No	ClinGen cosmic curated gnomAD
TCGA novel	1395	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA39739698 rs942617105	1397	P>L		No	ClinGen Ensembl
CA1471393 rs759055188	1397	P>S		No	ClinGen ExAC TOPMed gnomAD
CA345368734 rs1253637056	1399	L>F		No	ClinGen TOPMed
CA345368731 rs1392021037	1399	L>H		No	ClinGen TOPMed gnomAD
CA345368729 rs1392021037	1399	L>R		No	ClinGen TOPMed gnomAD
CA345368727 rs748240315	1400	V>F		No	ClinGen ExAC TOPMed gnomAD
rs748240315 CA1471390	1400	V>I		No	ClinGen ExAC TOPMed gnomAD
CA1471389 rs781334278	1402	L>V		No	ClinGen ExAC gnomAD
rs1246533734 CA345368703	1404	D>H		No	ClinGen TOPMed
rs1178856982 CA345368691	1405	T>I		No	ClinGen TOPMed gnomAD
rs369632116 CA1471388	1406	L>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs369632116 CA1471387	1406	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs779787737 CA1471386	1409	E>G		No	ClinGen ExAC TOPMed gnomAD
CA345368667 rs1392049404	1410	K>E		No	ClinGen gnomAD
rs750339435 CA1471384	1413	W>C		No	ClinGen ExAC gnomAD
CA345368637 rs1451994016	1414	I>V		No	ClinGen gnomAD
rs1572037160 CA345368631	1415	L>F		No	ClinGen Ensembl
rs1401720044 CA345368617	1417	I>F		No	ClinGen TOPMed gnomAD
rs1174575896 CA345368615	1417	I>T		No	ClinGen TOPMed gnomAD
rs1401720044 CA345368619	1417	I>V		No	ClinGen TOPMed gnomAD
CA345368604 rs138927825	1419	L>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs138927825 CA1471381	1419	L>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA345368577 rs763680391	1422	Q>H		No	ClinGen ExAC gnomAD
CA1471379 rs373830599	1423	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs373830599 CA39739657	1423	Y>F		No	ClinGen ESP ExAC TOPMed gnomAD
CA1471378 rs752434671	1425	T>A		No	ClinGen ExAC TOPMed gnomAD
rs1350839440 CA345368546	1427	T>K		No	ClinGen gnomAD
CA1471376 rs61736343	1430	A>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1438861064 CA345368524	1431	A>V		No	ClinGen TOPMed
rs653737 CA1471374 VAR_049332	1433	Y>C		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs653737 CA345368513	1433	Y>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1392831651 CA345368501	1435	E>G		No	ClinGen gnomAD
CA1471372 rs530429868	1435	E>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs988909957 CA345368474	1437	D>G		No	ClinGen gnomAD
rs988909957 CA39739036	1437	D>V		No	ClinGen gnomAD
CA345368475 rs1339998847	1437	D>Y		No	ClinGen TOPMed gnomAD
CA39739025 rs992253018	1440	L>V		No	ClinGen TOPMed
CA345368442 rs1212509177	1442	A>T		No	ClinGen TOPMed gnomAD
CA39738965 rs369162017	1443	D>E		No	ClinGen ESP TOPMed
rs868490953 CA39738999 COSM1193461	1443	D>H	lung [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
rs868490953 CA39739006	1443	D>N		No	ClinGen TOPMed gnomAD
CA1471357 rs199902201	1444	T>S		No	ClinGen 1000Genomes ExAC gnomAD
CA345368421 rs1375194354	1445	E>D		No	ClinGen TOPMed
CA345368418 rs1558180959	1446	F>L		No	ClinGen Ensembl
TCGA novel	1449	S>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1471354 rs777239211	1455	S>G		No	ClinGen ExAC TOPMed gnomAD
rs760867644 CA1471352	1455	S>N		No	ClinGen ExAC gnomAD
CA1471355 rs777239211	1455	S>R		No	ClinGen ExAC TOPMed gnomAD
CA1471353 rs760867644	1455	S>T		No	ClinGen ExAC gnomAD
rs1376336041 CA345368341	1456	V>G		No	ClinGen gnomAD
rs1304120983 CA345368335	1457	Q>L		No	ClinGen gnomAD
rs1448273421 CA345368329	1458	H>P		No	ClinGen gnomAD
CA345368328 rs1448273421	1458	H>R		No	ClinGen gnomAD
rs1353513012 CA345368316	1460	I>L		No	ClinGen gnomAD
rs1572036731 CA345368298	1462	S>N		No	ClinGen Ensembl
TCGA novel	1464	M>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1471350 rs772217461	1464	M>L		No	ClinGen ExAC TOPMed gnomAD
CA1471351 rs772217461	1464	M>V		No	ClinGen ExAC TOPMed gnomAD
rs778638153 CA1471348	1466	I>T		No	ClinGen ExAC gnomAD
TCGA novel	1470	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs145126908 CA39738891	1471	L>I		No	ClinGen ESP TOPMed
rs749157445 CA1471346	1477	K>E		No	ClinGen ExAC gnomAD
CA39737442 rs202229409	1480	T>N		No	ClinGen gnomAD
rs1012986973 CA39737435	1481	I>F		No	ClinGen TOPMed gnomAD
CA1471332 rs759721801	1483	K>E		No	ClinGen ExAC TOPMed
CA345368138 rs1176997174	1484	A>T		No	ClinGen gnomAD
rs1441816546 CA345368133	1484	A>V		No	ClinGen gnomAD
CA39737410 rs887259459	1488	N>S		No	ClinGen TOPMed gnomAD
rs774604488 CA345368099	1489	K>N		No	ClinGen ExAC TOPMed gnomAD
CA345368092 rs1469602488 COSM1501682	1490	S>I	lung Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed
rs1487728140 CA345368064	1494	E>A		No	ClinGen gnomAD
rs1267684304 CA345368041	1497	L>V		No	ClinGen TOPMed gnomAD
CA39737390 rs772883589	1501	N>K		No	ClinGen ExAC gnomAD
rs1415821952 CA345368005	1502	V>A		No	ClinGen TOPMed
rs769711703 CA1471327	1502	V>I		No	ClinGen ExAC gnomAD
COSM680018 CA1471326 rs748116286	1503	E>D	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
TCGA novel	1503	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345367995 rs1377116635	1504	T>A		No	ClinGen gnomAD
CA345367991 rs1302271532	1504	T>I		No	ClinGen gnomAD
rs1302271532 CA345367993	1504	T>N		No	ClinGen gnomAD
CA1471324 rs184859593	1508	K>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA345367954 rs1294028344	1509	Q>H		No	ClinGen gnomAD
rs746638530 CA345367945	1511	R>L		No	ClinGen ExAC TOPMed gnomAD
CA1471323 rs746638530	1511	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1558180469 CA345367947	1511	R>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs139925165 CA1471322	1512	H>R		No	ClinGen ESP ExAC gnomAD
rs1421618596 CA345367927	1514	K>E		No	ClinGen TOPMed gnomAD
CA345367924 rs1215431003	1514	K>T		No	ClinGen gnomAD
CA39737341 rs1036691248	1517	S>L		No	ClinGen TOPMed
rs60654480 CA39737338	1518	V>M		No	ClinGen Ensembl
TCGA novel	1519	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1198430500 CA345367889	1520	F>L		No	ClinGen gnomAD
CA1471319 rs764382158	1520	F>S		No	ClinGen ExAC TOPMed gnomAD
rs1052351099 CA39737320	1521	M>T		No	ClinGen Ensembl
CA1471318 rs756566799	1522	S>C		No	ClinGen ExAC TOPMed gnomAD
CA345367866 rs1226978844	1523	Q>R		No	ClinGen TOPMed
CA39737301 rs935286118	1525	L>Q		No	ClinGen Ensembl
rs753240557 CA1471317	1526	S>C		No	ClinGen ExAC TOPMed gnomAD
CA1471315 rs759666486	1527	S>Y		No	ClinGen ExAC gnomAD
rs1206821957 CA345367838	1528	N>S		No	ClinGen TOPMed
CA1471313 rs766555347	1530	F>L		No	ClinGen ExAC gnomAD
rs766555347 CA1471314	1530	F>V		No	ClinGen ExAC gnomAD
rs761758927 CA1471290	1534	V>I		No	ClinGen ExAC gnomAD
rs776704912 CA1471289	1535	V>F		No	ClinGen ExAC gnomAD
rs1329586617 CA345367766	1537	S>G		No	ClinGen TOPMed
rs202240841 CA1471288	1538	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs144406835 CA1471287	1540	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA345367743 rs1314926775	1541	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA1471286 rs558088674	1542	I>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs978845326 CA39734842	1542	I>T		No	ClinGen Ensembl
rs1404560163 CA345367730	1543	L>I		No	ClinGen TOPMed gnomAD
CA345367710 rs1303645889	1545	G>V		No	ClinGen gnomAD
CA1471285 rs143058283	1548	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs745508834 CA1471284	1549	R>K		No	ClinGen ExAC gnomAD
CA345367671 rs747825875	1549	R>S		No	ClinGen TOPMed gnomAD
rs1239665403 CA345367664	1550	L>F		No	ClinGen gnomAD
rs201149006 CA39733505	1552	E>G		No	ClinGen gnomAD
CA345367646 rs1447897162	1553	T>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA345367648 rs1447897162	1553	T>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs996901705 CA39733486	1554	V>I		No	ClinGen TOPMed gnomAD
rs758501854 CA1471258	1556	G>D		No	ClinGen ExAC gnomAD
CA1471259 rs780485939	1556	G>S		No	ClinGen ExAC gnomAD
CA1471257 rs745869843	1557	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA345367622 rs1572033771	1558	I>V		No	ClinGen Ensembl
CA1471256 VAR_049333 rs6661946	1559	S>N		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA345367616 rs1167871951	1559	S>R		No	ClinGen TOPMed gnomAD
CA345367586 rs1477565601	1563	Q>R		No	ClinGen gnomAD
rs754148431 CA345367576	1565	M>L		No	ClinGen ExAC gnomAD
CA1471253 rs763953610	1565	M>T		No	ClinGen ExAC TOPMed gnomAD
CA1471254 rs754148431	1565	M>V		No	ClinGen ExAC gnomAD
rs865968890 CA39733439	1566	E>*		No	ClinGen Ensembl
rs752673708 CA1471251	1569	A>T		No	ClinGen ExAC gnomAD
TCGA novel	1569	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs77776078 CA1471250	1570	D>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA345367526 rs1412859088	1572	L>F		No	ClinGen TOPMed
rs201834812 CA1471248	1574	V>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1471247 rs374099305	1575	K>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs531736484 CA39733408	1575	K>R		No	ClinGen Ensembl
rs762559378 CA1471246	1577	W>C		No	ClinGen ExAC gnomAD
CA39733373 rs984400999	1578	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs772902702 CA1471245	1578	R>H		No	ClinGen ExAC TOPMed gnomAD
CA1471243 rs747400321 COSM210458	1579	A>T	Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
rs775927959 CA1471242	1579	A>V		No	ClinGen ExAC TOPMed gnomAD
CA345367477 rs1267319358	1580	L>P		No	ClinGen TOPMed gnomAD
CA345367470 rs1447974172	1581	L>R		No	ClinGen TOPMed
rs1280214886 CA345367474	1581	L>V		No	ClinGen TOPMed
CA1471240 rs746403332	1582	S>G		No	ClinGen ExAC gnomAD
rs1422749115 CA345367444	1585	Y>C		No	ClinGen TOPMed gnomAD
CA345367446 rs1478251909	1585	Y>H		No	ClinGen gnomAD
CA1471237 rs749505335	1586	D>E		No	ClinGen ExAC TOPMed gnomAD
CA39733325 rs911587372	1586	D>N		No	ClinGen Ensembl
CA39733323 rs987032753	1588	L>F		No	ClinGen Ensembl
rs756359423 CA1471235	1590	K>E		No	ClinGen ExAC TOPMed gnomAD
CA1471217 rs141660503	1592	N>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1195565660 CA345367381	1593	A>T		No	ClinGen TOPMed
rs775049727 CA1471216	1594	L>S		No	ClinGen ExAC
CA1471215 rs771127536	1599	T>I		No	ClinGen ExAC gnomAD
rs769856164 CA1471212	1602	P>L		No	ClinGen ExAC gnomAD
CA345367325 rs1257861054	1602	P>S		No	ClinGen gnomAD
CA345367320 rs1320556324	1603	V>L		No	ClinGen gnomAD
TCGA novel	1604	I>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1471211 rs748433436	1606	G>E		No	ClinGen ExAC gnomAD
rs780817490 CA1471210	1608	V>A		No	ClinGen ExAC TOPMed gnomAD
CA39732915 rs935067724	1608	V>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA1471209 rs754814133	1610	N>S		No	ClinGen ExAC TOPMed gnomAD
CA39732896 rs890221877	1611	P>A		No	ClinGen TOPMed
rs1394760409 CA345367273	1611	P>H		No	ClinGen TOPMed
CA345367274 rs890221877	1611	P>S		No	ClinGen TOPMed
CA39732897 rs890221877	1611	P>T		No	ClinGen TOPMed
CA345367254 rs1366209678	1614	S>C		No	ClinGen TOPMed
rs372362755 CA1471206	1616	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs749879063 CA1471205	1616	R>H	Variant assessed as Somatic; 4.631e-05 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA1471204 rs571188259 COSM161480	1617	R>C	breast [Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD
CA1471203 rs753570196	1617	R>H		No	ClinGen ExAC TOPMed gnomAD
rs753570196 CA1471202	1617	R>L		No	ClinGen ExAC TOPMed gnomAD
rs368599342 CA1471201	1618	K>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA39732822 rs760041607	1619	A>G		No	ClinGen ExAC TOPMed gnomAD
rs1469084427 CA345367231	1619	A>T		No	ClinGen TOPMed
CA1471200 rs760041607	1619	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA39732817 rs144518221	1621	D>Y		No	ClinGen 1000Genomes ESP TOPMed
TCGA novel	1624	N>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1471197 rs375244010	1627	L>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA1471195 rs769956169	1629	Q>H		No	ClinGen ExAC gnomAD
rs115054974 CA1471194	1630	N>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs371868580 CA1471193	1630	N>S		No	ClinGen ESP ExAC
CA345367154 rs1175488987	1631	I>V		No	ClinGen TOPMed gnomAD
CA1471192 rs560393274	1636	T>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA345367112 rs1291453466	1637	I>V		No	ClinGen gnomAD
CA1471176 rs143980201	1640	R>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1471175 rs143980201	1640	R>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs374894422 CA1471174	1640	R>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA345367067 rs1317256006	1642	L>P		No	ClinGen gnomAD
CA345367054 rs1300385823	1644	L>P		No	ClinGen gnomAD
CA345367052 rs1384881656	1645	V>I		No	ClinGen gnomAD
CA345367045 rs747254483	1646	P>A		No	ClinGen ExAC TOPMed gnomAD
CA1471173 rs747254483	1646	P>S		No	ClinGen ExAC TOPMed gnomAD
rs771898737 CA1471171	1651	I>M		No	ClinGen ExAC gnomAD
rs1455577056 CA345367008	1652	V>L		No	ClinGen gnomAD
CA345366998 rs1450099677	1653	Q>R		No	ClinGen TOPMed gnomAD
rs745773701 CA1471170	1654	R>C		No	ClinGen ExAC TOPMed gnomAD
rs16833884 CA1471169 VAR_049334	1654	R>H		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs1047753808 CA39732160	1655	K>N		No	ClinGen TOPMed gnomAD
rs757143929 CA1471168	1658	E>D		No	ClinGen ExAC gnomAD
CA345366937 rs1487670668	1662	E>Q		No	ClinGen gnomAD
CA345366929 rs1260501927	1663	Q>E		No	ClinGen gnomAD
rs1485960193 CA345366911	1665	I>M		No	ClinGen gnomAD
rs777443144 CA1471166	1665	I>V		No	ClinGen ExAC gnomAD
CA1471165 rs140846433	1666	N>D		No	ClinGen ESP ExAC TOPMed gnomAD
CA345366901 rs1230701256	1667	R>K		No	ClinGen gnomAD
rs766828466 CA1471163	1669	T>I		No	ClinGen ExAC gnomAD
rs758853810 CA1471162	1670	A>T		No	ClinGen ExAC TOPMed gnomAD
rs201522356 CA1471161	1670	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs762242781 CA1471159	1672	Y>C		No	ClinGen ExAC gnomAD
rs776644219 CA1471158	1673	T>S		No	ClinGen ExAC TOPMed gnomAD
rs764190523 CA1471157	1674	L>F		No	ClinGen ExAC gnomAD
CA345366854 rs1464809426	1675	K>E		No	ClinGen gnomAD
TCGA novel	1679	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1471156 rs768268042	1680	N>S		No	ClinGen ExAC TOPMed gnomAD
CA345366815 rs1408837747	1680	N>Y		No	ClinGen gnomAD
rs145196748 CA1471155	1681	F>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	1682	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs771843600 CA1471154	1682	G>S		No	ClinGen ExAC TOPMed gnomAD
rs745745797 CA1471153	1685	N>K		No	ClinGen ExAC TOPMed gnomAD
rs774027857 CA1471152	1686	P>L		No	ClinGen ExAC gnomAD
rs770851065 CA1471151	1687	D>N		No	ClinGen ExAC gnomAD
CA1471150 rs61730303	1688	P>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1471149 rs777384144	1689	F>L		No	ClinGen ExAC gnomAD
rs978371898 CA39732013	1690	V>I		No	ClinGen TOPMed gnomAD
CA1471148 rs755733796	1691	P>S		No	ClinGen ExAC gnomAD
CA1471147 rs747788869	1693	L>P		No	ClinGen ExAC gnomAD
CA345366732 rs1327119522	1694	N>D		No	ClinGen gnomAD
rs2275689 CA345366729	1694	N>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
VAR_010939 CA1471145 rs2275689	1694	N>S		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs199577251 CA1471144	1695	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs779168536 CA1471143	1696	A>G		No	ClinGen ExAC gnomAD
CA345366716 rs1204014051	1697	V>M		No	ClinGen gnomAD
rs1170160270 CA345366697	1700	I>L		No	ClinGen gnomAD
rs1338324379 CA345366689	1701	A>P		No	ClinGen TOPMed
CA1471139 rs538257249	1701	A>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1471138 rs752915456	1702	P>A		No	ClinGen ExAC gnomAD
rs767718178 CA1471137	1705	K>E		No	ClinGen ExAC gnomAD
rs767718178 CA345366665	1705	K>Q		No	ClinGen ExAC gnomAD
CA345366662 rs1217920071	1705	K>T		No	ClinGen gnomAD
rs771356015 CA39731902	1706	E>G		No	ClinGen Ensembl
rs781364360	1707	E>missing	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
CA345366623 rs1340153746	1710	V>A		No	ClinGen gnomAD
rs1016008604 CA39731858	1712	G>E		No	ClinGen Ensembl
COSM302356 rs367715127 CA1471132	1714	A>T	central_nervous_system Variant assessed as Somatic; 0.000231 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
CA1471131 rs143495736	1714	A>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs768305604 CA1471127	1717	C>F		No	ClinGen ExAC gnomAD
rs780863741 CA1471128	1717	C>G		No	ClinGen ExAC gnomAD
rs1160899832 CA345366582	1718	I>V		No	ClinGen gnomAD
rs1426042385 CA345366572	1719	A>G		No	ClinGen gnomAD
rs746674579 CA1471126	1721	V>A		No	ClinGen ExAC gnomAD
CA39731819 rs779306731	1724	T>A		No	ClinGen ExAC TOPMed gnomAD
rs780292286 CA39731817	1724	T>I		No	ClinGen TOPMed gnomAD
CA1471125 rs779306731	1724	T>P	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
COSM311734 rs200302789 CA1471123	1727	A>V	lung Variant assessed as Somatic; 4.626e-05 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated 1000Genomes ESP NCI-TCGA TOPMed gnomAD
CA345366519 rs1304964710	1729	A>T		No	ClinGen TOPMed
CA1471120 rs778323422	1730	I>M		No	ClinGen ExAC TOPMed gnomAD
rs940740518 CA39731774	1730	I>T		No	ClinGen TOPMed
rs754332969 CA1471121	1730	I>V		No	ClinGen ExAC gnomAD
CA345366500 rs1220258090	1732	Q>P		No	ClinGen TOPMed gnomAD
rs756621877 CA1471119	1734	P>S		No	ClinGen ExAC gnomAD
rs1474470215 CA345366449	1738	P>A		No	ClinGen gnomAD
CA1471089 rs748413550	1738	P>L		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	1738	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA39730906 rs867845140	1739	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA1471087 rs79408620	1741	L>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA39730901 rs914931018	1743	T>A		No	ClinGen TOPMed
CA1471086 rs760172644	1744	M>I		No	ClinGen ExAC gnomAD
CA345366414 rs1558177632	1744	M>R		No	ClinGen Ensembl
rs1324841663 CA345366406	1745	K>R		No	ClinGen gnomAD
rs1257978297 CA345366394	1747	T>P		No	ClinGen gnomAD
rs199987609 CA1471085	1748	S>C		No	ClinGen 1000Genomes ExAC
CA1471082 rs773530434	1749	E>G		No	ClinGen ExAC TOPMed gnomAD
CA1471083 rs745546689	1749	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1465069214 CA345366372	1750	L>P		No	ClinGen Ensembl
TCGA novel	1753	S>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345366343 rs1572032254	1754	E>D		No	ClinGen Ensembl
rs1380292702 CA345366346	1754	E>G		No	ClinGen gnomAD
rs1303101968 CA345366350	1754	E>K		No	ClinGen gnomAD
rs1380292702 CA345366345	1754	E>V		No	ClinGen gnomAD
CA1471078 rs781615267	1756	Y>C		No	ClinGen ExAC TOPMed gnomAD
CA1471079 rs781615267	1756	Y>S		No	ClinGen ExAC TOPMed gnomAD
rs915546188 CA345366329	1757	L>V		No	ClinGen gnomAD
rs1335760573 CA345366316	1759	S>N		No	ClinGen TOPMed
CA39730862 rs149534672	1762	A>P		No	ClinGen ESP ExAC TOPMed gnomAD
rs149534672 CA1471076	1762	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA345366271 rs1572032228	1766	K>R		No	ClinGen Ensembl
CA39730853 rs991135883	1768	V>A		No	ClinGen Ensembl
rs1472623568 CA345366251	1769	E>G		No	ClinGen gnomAD
rs1572032213 CA345366248	1770	T>P		No	ClinGen Ensembl
CA345366241 rs1185737781	1771	L>V		No	ClinGen gnomAD
CA1471073 rs185953741	1772	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs758655047 CA1471074	1772	P>S		No	ClinGen ExAC gnomAD
rs757179796 CA1471071	1773	H>P		No	ClinGen ExAC gnomAD
CA39730813 rs747631529	1773	H>Q		No	ClinGen TOPMed gnomAD
rs763874754 CA345366218	1775	I>L		No	ClinGen ExAC TOPMed gnomAD
rs763874754 CA1471069	1775	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1356741623 CA345366201	1777	P>L		No	ClinGen TOPMed gnomAD
CA345366199 rs1356741623	1777	P>R		No	ClinGen TOPMed gnomAD
CA1471068 rs577396019	1778	Y>C		No	ClinGen 1000Genomes ExAC gnomAD
rs577396019 CA39730759	1778	Y>S		No	ClinGen 1000Genomes ExAC gnomAD
rs1021543535 CA39730752	1779	L>R		No	ClinGen TOPMed
rs966901854 CA345366191	1779	L>V		No	ClinGen gnomAD
CA345366177 rs1172186171	1781	G>D		No	ClinGen gnomAD
rs11542406 CA39730742	1784	S>F		No	ClinGen Ensembl
rs767050699 CA1471066	1784	S>P		No	ClinGen ExAC gnomAD
rs886805974 CA39729935	1786	V>M		No	ClinGen TOPMed
rs1479151955 CA345365932	1787	I>M		No	ClinGen gnomAD
rs761065481 CA1471041	1787	I>S		No	ClinGen ExAC gnomAD
CA345365930 rs1403706215	1788	H>D		No	ClinGen gnomAD
CA345365931 rs1403706215	1788	H>N		No	ClinGen gnomAD
rs776199324 CA345365925	1788	H>Q		No	ClinGen ExAC TOPMed gnomAD
CA345365927 rs1270494265	1788	H>R		No	ClinGen gnomAD
CA345365921 rs1487723513	1789	L>P		No	ClinGen gnomAD
TCGA novel	1791	K>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1471039 rs772276212	1792	I>M		No	ClinGen ExAC gnomAD
TCGA novel	1794	S>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1471037 rs779151020	1794	S>N		No	ClinGen ExAC gnomAD
rs771014021 CA1471036	1796	M>I		No	ClinGen ExAC gnomAD
rs267598429 CA39729908	1796	M>T		No	ClinGen Ensembl
rs1339013903 CA345365865	1797	G>A		No	ClinGen TOPMed
TCGA novel	1798	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1471035 rs749561310	1799	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1324225336 COSM364248 CA345365846	1800	S>L	lung [Cosmic]	No	ClinGen cosmic curated gnomAD
CA1471032 rs752623367	1802	A>V		No	ClinGen ExAC gnomAD
CA39729852 rs898228775	1803	N>D		No	ClinGen TOPMed
rs781039116 CA1471031	1803	N>I		No	ClinGen ExAC gnomAD
CA1471030 rs754921244	1804	I>T		No	ClinGen ExAC gnomAD
rs900803615 CA39729840	1805	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs752629897 CA1471029	1805	R>H		No	ClinGen ExAC TOPMed gnomAD
rs765905193 CA1471028	1807	T>I		No	ClinGen ExAC gnomAD
CA345365797 rs1199421366	1809	L>F	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs371729329 CA1471027	1810	K>E		No	ClinGen ESP ExAC TOPMed gnomAD
rs1478167017 CA345365785	1811	K>E		No	ClinGen TOPMed
rs750140316 CA1471026	1811	K>N		No	ClinGen ExAC gnomAD
rs1572031638 CA345365769	1813	L>R		No	ClinGen Ensembl
CA345365772 rs1486071982	1813	L>V		No	ClinGen TOPMed gnomAD
CA345365765 rs776004580	1814	A>G		No	ClinGen ExAC gnomAD
rs761171133 CA1471024	1814	A>T		No	ClinGen ExAC gnomAD
CA1471023 rs776004580	1814	A>V		No	ClinGen ExAC gnomAD
CA345365760 rs772652823	1815	T>I		No	ClinGen ExAC gnomAD
CA1471022 rs772652823	1815	T>N		No	ClinGen ExAC gnomAD
rs1263713806 CA345365758	1816	T>A		No	ClinGen TOPMed gnomAD
rs1263713806 CA345365759	1816	T>P		No	ClinGen TOPMed gnomAD
CA345365751 rs1468817343	1817	L>F		No	ClinGen TOPMed
CA345365742 rs1325980331	1818	A>V		No	ClinGen gnomAD
TCGA novel	1819	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1039419321 CA39729752	1820	R>*		No	ClinGen TOPMed
rs1384201484 CA345365732	1820	R>L		No	ClinGen gnomAD
CA39729733 rs370642722	1821	V>G		No	ClinGen Ensembl
rs774536593 CA1471020 COSM1185797	1821	V>I	lung [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA345365726 rs1468568189	1822	L>V		No	ClinGen gnomAD
CA345365719 rs1294610250	1823	L>S		No	ClinGen TOPMed
CA39729722 rs910786626	1824	P>S		No	ClinGen Ensembl
rs1461020545 CA345365707	1825	A>G		No	ClinGen gnomAD
CA1471017 rs145363555	1825	A>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA345365706 rs1461020545	1825	A>V		No	ClinGen gnomAD
rs933561107 CA39729711	1826	I>V		No	ClinGen TOPMed gnomAD
rs139348840 CA1471016	1827	K>E		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	1829	T>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA1471015 rs747877876	1832	Q>*		No	ClinGen ExAC gnomAD
CA345365648 rs1181485480	1834	E>K		No	ClinGen gnomAD
TCGA novel	1837	W>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs780985866 CA1471014	1838	K>R		No	ClinGen ExAC TOPMed gnomAD
CA39729430 rs572297921	1839	N>T		No	ClinGen 1000Genomes
rs1298933572 CA345365587	1840	H>Y		No	ClinGen TOPMed
rs1558176988 CA345365576	1841	M>I		No	ClinGen Ensembl
rs370868615 CA1470996	1841	M>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA1470995 rs768488556	1842	G>D		No	ClinGen ExAC TOPMed gnomAD
CA1470994 rs375911763	1843	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA39729419 rs1010370512	1843	P>S		No	ClinGen Ensembl
CA345365558 CA345365557 rs1331490680	1844	F>L		No	ClinGen gnomAD
TCGA novel	1852	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345365489 rs1252688014	1853	G>A		No	ClinGen TOPMed
CA345365492 rs1204860853	1853	G>R		No	ClinGen TOPMed
CA1470991 rs1885533 VAR_010940	1854	V>A		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs1885533 CA39729372	1854	V>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1885533 CA39729338	1854	V>G		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs201959745 CA1470992	1854	V>M		No	ClinGen 1000Genomes ExAC
CA345365466 rs1365822072	1855	M>I		No	ClinGen gnomAD
CA1470990 rs778311867	1856	K>E		No	ClinGen ExAC gnomAD
rs181086746 CA1470989	1857	K>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA39729296 rs892728122	1860	L>V		No	ClinGen TOPMed gnomAD
CA1470988 rs753588336	1861	T>I		No	ClinGen ExAC gnomAD
CA1470987 rs767975912	1862	S>P		No	ClinGen ExAC gnomAD
CA1470986 rs755457626	1864	Q>L		No	ClinGen ExAC TOPMed gnomAD
rs1220374257 CA345365337	1865	S>F		No	ClinGen gnomAD
TCGA novel	1865	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1410323461 CA345365323	1866	Q>R		No	ClinGen TOPMed
CA1470985 rs751872020	1868	T>A		No	ClinGen ExAC
rs375609616 CA1470983	1869	A>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA345365284 rs1460619830	1869	A>V		No	ClinGen TOPMed
rs1885532 CA345365254 CA345365253	1873	E>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1558176920 CA345365249	1874	A>V		No	ClinGen Ensembl
CA1470979 rs776896499	1877	F>I		No	ClinGen ExAC gnomAD
rs149306902 CA1470978	1877	F>L		No	ClinGen ESP ExAC TOPMed
CA345365223 rs1382579222	1878	R>Q		No	ClinGen TOPMed
rs1215536758 CA345365218	1879	A>G		No	ClinGen TOPMed
CA345365198 rs1275475348	1882	S>A		No	ClinGen TOPMed
CA39729233 rs113612434	1882	S>C		No	ClinGen ExAC TOPMed gnomAD
rs113612434 CA1470976	1882	S>F		No	ClinGen ExAC TOPMed gnomAD
CA345365136 rs536014077	1885	D>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1470955 rs536014077	1885	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA345365111 rs1174397096	1887	E>K		No	ClinGen TOPMed
rs748746097 CA1470953	1891	K>E		No	ClinGen ExAC gnomAD
CA39729029 rs201518919	1892	T>M		No	ClinGen TOPMed gnomAD
CA1470951 rs202009039	1894	N>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA39729016 rs747794433	1895	C>F		No	ClinGen ExAC TOPMed gnomAD
CA1470950 rs747794433	1895	C>Y		No	ClinGen ExAC TOPMed gnomAD
rs201515471 CA1470947	1896	I>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA1470948 rs758748046	1896	I>T		No	ClinGen ExAC gnomAD
rs371888813 CA1470949	1896	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs1448743342 CA345364962	1897	I>M		No	ClinGen TOPMed gnomAD
CA1470946 rs531433512	1897	I>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1350741317 CA345364936	1899	C>S		No	ClinGen TOPMed
CA39728969 rs757776342	1902	A>P		No	ClinGen ExAC gnomAD
CA1470945 rs757776342	1902	A>S		No	ClinGen ExAC gnomAD
CA345364905 rs757776342	1902	A>T		No	ClinGen ExAC gnomAD
CA345364895 rs1421855611	1903	M>V		No	ClinGen gnomAD
rs764192480 CA1470943	1906	K>N		No	ClinGen ExAC TOPMed gnomAD
rs564113419 CA1470944	1906	K>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1281405216 CA345364846	1907	L>F		No	ClinGen gnomAD
CA345364833 rs1185948772	1908	S>T		No	ClinGen gnomAD
rs1232844834 CA345364820	1909	E>K		No	ClinGen gnomAD
CA1470941 rs752914800	1914	P>T		No	ClinGen ExAC gnomAD
rs1558176756 CA345364766	1915	L>V		No	ClinGen Ensembl
CA345364757 rs1197496485	1916	F>Y		No	ClinGen TOPMed
CA1470918 rs766238122	1921	D>N		No	ClinGen ExAC gnomAD
rs1316172426 CA345364695	1923	A>S		No	ClinGen gnomAD
CA1470917 rs763007557	1923	A>V		No	ClinGen ExAC gnomAD
CA345364668 rs1382956164	1927	D>A		No	ClinGen gnomAD
COSM123554 CA1470916 rs368602949	1927	D>H	upper_aerodigestive_tract [Cosmic]	No	ClinGen cosmic curated ESP ExAC TOPMed gnomAD
CA39728768 rs937433330	1930	K>E		No	ClinGen Ensembl
rs747790372 CA39728759	1931	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA1470915 rs764808973	1938	N>S		No	ClinGen ExAC TOPMed gnomAD
CA1470914 rs140571212	1940	A>V		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	1941	D>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345364572 rs1295560317	1941	D>G		No	ClinGen gnomAD
CA39728714 rs1053130829	1941	D>N		No	ClinGen TOPMed gnomAD
CA345364566 rs1396784356	1942	C>G		No	ClinGen TOPMed
CA1470912 rs530149086	1943	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1345039209 CA345364554	1944	A>T		No	ClinGen gnomAD
CA345364527 rs1572031065	1948	K>E		No	ClinGen Ensembl
rs1413350615 CA345364516	1949	G>E		No	ClinGen TOPMed gnomAD
rs1198016968 CA345364492	1953	L>V		No	ClinGen gnomAD
CA39728691 rs202084979	1955	A>V		No	ClinGen TOPMed gnomAD
CA1470910 rs780852573 COSM906030	1956	G>S	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA39728620 rs913131943	1960	K>M		No	ClinGen Ensembl
rs771234251 CA1470909	1961	P>S		No	ClinGen ExAC gnomAD
CA345364426 rs1485417606	1963	A>D		No	ClinGen gnomAD
CA1470908 rs749806008	1965	T>A		No	ClinGen ExAC TOPMed gnomAD
rs1126627 VAR_010941 CA1470907	1967	N>D		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA345364403 rs1126627	1967	N>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA345364395 rs1262459460	1968	Q>E		No	ClinGen gnomAD
rs375302321 CA1470906	1968	Q>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA345364374 rs1321561173	1971	I>V		No	ClinGen gnomAD
rs1558176567 CA345364364	1972	S>Y		No	ClinGen Ensembl
CA1470904 rs781303735	1974	T>I		No	ClinGen ExAC gnomAD
rs193150310 CA345364334	1975	D>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs193150310 CA1470888	1975	D>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1404996491 CA345364314	1978	F>S		No	ClinGen gnomAD
TCGA novel	1979	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs781156435 CA1470886	1981	S>C		No	ClinGen ExAC gnomAD
rs768724570 CA1470885	1982	E>G		No	ClinGen ExAC gnomAD
CA345364281 rs747239592	1983	N>D		No	ClinGen ExAC gnomAD
CA1470884 rs747239592	1983	N>H		No	ClinGen ExAC gnomAD
CA1470883 rs780491577	1983	N>S		No	ClinGen ExAC gnomAD
CA39728090 rs767720192	1986	E>G		No	ClinGen Ensembl
rs1425417486 CA345364250	1987	K>R		No	ClinGen gnomAD
rs750291302 CA1470881	1989	C>R		No	ClinGen ExAC gnomAD
rs753757381 CA1470878	1993	Q>R		No	ClinGen ExAC gnomAD
rs760107933 CA1470876	1996	L>F		No	ClinGen ExAC gnomAD
rs1244238449 CA345364174	1998	C>G		No	ClinGen gnomAD
CA345364165 rs1330695900	1999	L>S		No	ClinGen TOPMed
rs554279956 CA1470875	2000	Y>H		No	ClinGen ExAC gnomAD
rs377069832 CA39728000	2002	I>V		No	ClinGen gnomAD
CA39727992 rs201968820	2004	L>F		No	ClinGen 1000Genomes ExAC gnomAD
rs201968820 CA1470874	2004	L>I		No	ClinGen 1000Genomes ExAC gnomAD
rs759161350 CA1470873	2004	L>P		No	ClinGen ExAC TOPMed gnomAD
CA1470872 rs773482506	2005	F>C		No	ClinGen ExAC gnomAD
CA345364125 rs773482506	2005	F>S		No	ClinGen ExAC gnomAD
TCGA novel	2005	F>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs759536976 CA39727976	2008	Q>R		No	ClinGen Ensembl
CA345364099 rs1364578060	2009	H>Y		No	ClinGen gnomAD
rs770148279 CA1470871	2010	F>L		No	ClinGen ExAC gnomAD
CA345364084 rs1473669843	2011	I>V		No	ClinGen gnomAD
CA1470870 rs142962546	2012	S>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA1470869 rs777130681	2013	K>E		No	ClinGen ExAC gnomAD
CA1470868 rs769281615	2013	K>R		No	ClinGen ExAC gnomAD
CA1470867 rs747143393	2015	R>G		No	ClinGen ExAC gnomAD
rs2275687 VAR_010942 CA1470865	2017	E>G	confirmed at protein level [UniProt]	No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs780258588 CA345364043	2017	E>K		No	ClinGen ExAC TOPMed gnomAD
rs780258588 CA1470866	2017	E>Q		No	ClinGen ExAC TOPMed gnomAD
rs1474642659 CA345364031	2019	L>M		No	ClinGen TOPMed gnomAD
rs778592048 CA1470863	2020	M>V		No	ClinGen ExAC TOPMed gnomAD
rs1266544715 CA345364015	2021	M>V		No	ClinGen gnomAD
rs749182893 CA1470861	2023	L>V		No	ClinGen ExAC gnomAD
rs1378460333 CA345363748	2030	R>S		No	ClinGen TOPMed gnomAD
CA39726982 rs868294301	2031	L>R		No	ClinGen Ensembl
CA1470836 rs377007553	2032	G>A		No	ClinGen ESP ExAC TOPMed gnomAD
rs377007553 CA39726955	2032	G>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA39726947 rs766115066	2034	E>D		No	ClinGen ExAC TOPMed gnomAD
rs535809628 CA1470834	2034	E>Q		No	ClinGen 1000Genomes ExAC gnomAD
TCGA novel	2035	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs754270047 CA1470831	2036	K>R		No	ClinGen ExAC gnomAD
CA345363696 rs1572030098	2038	Q>H		No	ClinGen Ensembl
CA345363685 rs1345230897	2040	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs764511774 CA1470830	2040	R>W		No	ClinGen ExAC gnomAD
rs1269248459 CA345363680	2041	V>L		No	ClinGen TOPMed gnomAD
COSM906028 rs370884856 CA1470829	2042	T>A	endometrium [Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD
CA345363673 rs1321128663	2042	T>R		No	ClinGen gnomAD
rs1451759966 CA345363661	2044	H>Y		No	ClinGen gnomAD
CA345363655 rs139022059	2045	L>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA1470827 rs139022059	2045	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs1484107335 CA345363641	2047	P>R		No	ClinGen TOPMed
rs774279258 CA1470825	2047	P>S		No	ClinGen ExAC TOPMed gnomAD
rs145985095 CA1470822	2050	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA345363610 rs1189624247	2052	F>I		No	ClinGen gnomAD
CA1470821 rs571460036 COSM1296037	2052	F>L	urinary_tract [Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD
CA39726865 rs904429521	2053	S>L		No	ClinGen TOPMed
rs1236260623 CA345363604	2053	S>P		No	ClinGen gnomAD
TCGA novel	2055	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA345363583 rs1572030032	2056	M>T		No	ClinGen Ensembl
CA345363573 rs1202659903	2057	A>V		No	ClinGen gnomAD
CA1470817 rs560358292	2058	D>N		No	ClinGen 1000Genomes ExAC gnomAD
CA1470816 rs200320031	2060	S>C		No	ClinGen ExAC TOPMed gnomAD
CA345363553 rs200320031	2060	S>F		No	ClinGen ExAC TOPMed gnomAD
CA1470815 rs149145208	2062	W>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA1470814 rs750045686	2068	Q>E		No	ClinGen ExAC TOPMed gnomAD
CA345363500 rs1450263590	2068	Q>R		No	ClinGen TOPMed gnomAD
rs778294435 CA1470813	2069	I>T		No	ClinGen ExAC gnomAD
rs1279244963 CA345363476	2072	K>R		No	ClinGen TOPMed
rs753104315 CA1470811	2073	T>A		No	ClinGen ExAC gnomAD
CA1470810 rs200854169 COSM210457	2073	T>M	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
rs1424446321 CA345363460	2075	D>N		No	ClinGen gnomAD
rs751695334 CA1470808	2075	D>V		No	ClinGen ExAC gnomAD
rs763252172 CA345363450	2076	S>C		No	ClinGen ExAC TOPMed gnomAD
CA1470806 rs763252172	2076	S>F		No	ClinGen ExAC TOPMed gnomAD
rs6664730 CA1470804 VAR_049335	2077	S>L		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
CA345363446 rs6664730	2077	S>W		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA345363442 rs1274942821	2078	P>S		No	ClinGen gnomAD
rs776388967 CA1470802	2079	K>E		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	2081	R>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs761992655 CA1470781	2081	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs530544216 CA1470780	2083	A>V		No	ClinGen 1000Genomes ExAC gnomAD
CA1470778 rs760672777	2087	T>A		No	ClinGen ExAC gnomAD
CA1470777 rs563013149	2088	V>E		No	ClinGen 1000Genomes ExAC gnomAD
rs150966685 CA39723563	2089	L>V		No	ClinGen ESP TOPMed gnomAD
CA345363354 rs1426862625	2090	A>V		No	ClinGen gnomAD
rs367618061 CA345363353	2091	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	2093	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs773972406 CA1470774	2095	L>V		No	ClinGen ExAC gnomAD
CA345363318 rs1210586627	2096	K>R		No	ClinGen gnomAD
CA1470773 rs770743522	2097	E>D		No	ClinGen ExAC TOPMed gnomAD
rs748903503 CA1470772	2098	N>K		No	ClinGen ExAC gnomAD
TCGA novel	2099	Y>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs977899516 CA39723534	2101	V>I		No	ClinGen gnomAD
CA1470771 rs781633733	2104	P>R		No	ClinGen ExAC gnomAD
rs770323233 CA39723487	2106	S>F		No	ClinGen Ensembl
rs1327569859 CA345363230	2109	F>L		No	ClinGen TOPMed
CA345363210 rs1572028364	2112	E>D		No	ClinGen Ensembl
rs1296032739 CA345363205	2113	L>S		No	ClinGen gnomAD
rs752471097 CA1470728	2116	D>E		No	ClinGen ExAC
CA1470730 rs756334857	2116	D>G		No	ClinGen ExAC gnomAD
rs756334857 CA1470729	2116	D>V		No	ClinGen ExAC gnomAD
CA345363155 rs767378258	2117	E>*		No	ClinGen ExAC gnomAD
CA1470726 rs759562725	2117	E>D		No	ClinGen ExAC
rs767378258 CA1470727	2117	E>K		No	ClinGen ExAC gnomAD
rs200192734 CA1470725	2118	C>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs200192734 CA345363137	2118	C>Y		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA1470724 rs766419632	2120	E>V		No	ClinGen ExAC gnomAD
CA1470722 rs1553279570	2121	V>E		No	ClinGen Ensembl
CA1470721 rs148413430	2123	H>R		No	ClinGen ESP ExAC gnomAD
CA345363042 rs1340543684	2124	Q>H		No	ClinGen gnomAD
rs769374782 CA1470719	2129	I>V		No	ClinGen ExAC gnomAD
CA345362921 rs1388482480	2132	L>V		No	ClinGen TOPMed
CA1470717 rs2607	2133	E>K		No	ClinGen ExAC gnomAD
CA39722195 rs2607	2133	E>Q		No	ClinGen ExAC gnomAD
CA345362898 rs1408715279	2134	T>A		No	ClinGen gnomAD
rs997410827 CA39722172	2137	G>E		No	ClinGen gnomAD
rs1328302608 CA345362858	2138	E>Q		No	ClinGen TOPMed
rs573400289 CA39722161	2139	P>A		No	ClinGen TOPMed
CA1470715 rs746378086	2140	L>F		No	ClinGen ExAC gnomAD
rs771410489 CA1470713	2141	Q>*		No	ClinGen ExAC gnomAD
CA39722155 rs771410489	2141	Q>K		No	ClinGen ExAC gnomAD
rs1572026811 CA345362797	2142	S>N		No	ClinGen Ensembl
rs1385865727 CA345362788	2142	S>R		No	ClinGen TOPMed
CA345362778 rs1369016226	2143	Y>C		No	ClinGen gnomAD

No associated diseases with Q9H583

2 regional properties for Q9H583

Type	Name	Position	InterPro Accession
domain	PWWP domain	5 - 86	IPR000313
domain	Lens epithelium-derived growth factor, integrase-binding domain	472 - 569	IPR021567

Functions

		Description
EC Number
Subcellular Localization	Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

8 GO annotations of cellular component

Name	Definition
90S preribosome	A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
fibrillar center	A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
mitochondrion	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleolus	A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.
small-subunit processome	A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
t-UTP complex	A protein complex that forms a subcomplex of the 90S preribosome and is required for the subsequent assembly of the rest of the preribosome. In S. cerevisiae, it is composed of Utp5p, Utp4p, Nan1p, Utp8p, Utp9p, Utp10 and Utp15p.

2 GO annotations of molecular function

Name	Definition
RNA binding	Binding to an RNA molecule or a portion thereof.
snoRNA binding	Binding to a small nucleolar RNA.

3 GO annotations of biological process

Name	Definition
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
positive regulation of rRNA processing	Any process that activates or increases the frequency, rate or extent of rRNA processing.
positive regulation of transcription by RNA polymerase I	Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase I.

No homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins

10	20	30	40	50	60
MTSLAQQLQR	LALPQSDASL	LSRDEVASLL	FDPKEAATID	RDTAFAIGCT	GLEELLGIDP
70	80	90	100	110	120
SFEQFEAPLF	SQLAKTLERS	VQTKAVNKQL	DENISLFLIH	LSPYFLLKPA	QKCLEWLIHR
130	140	150	160	170	180
FHIHLYNQDS	LIACVLPYHE	TRIFVRVIQL	LKINNSKHRW	FWLLPVKQSG	VPLAKGTLIT
190	200	210	220	230	240
HCYKDLGFMD	FICSLVTKSV	KVFAEYPGSS	AQLRVLLAFY	ASTIVSALVA	AEDVSDNIIA
250	260	270	280	290	300
KLFPYIQKGL	KSSLPDYRAA	TYMIICQISV	KVTMENTFVN	SLASQIIKTL	TKIPSLIKDG
310	320	330	340	350	360
LSCLIVLLQR	QKPESLGKKP	FPHLCNVPDL	ITILHGISET	YDVSPLLHYM	LPHLVVSIIH
370	380	390	400	410	420
HVTGEETEGM	DGQIYKRHLE	AILTKISLKN	NLDHLLASLL	FEEYISYSSQ	EEMDSNKVSL
430	440	450	460	470	480
LNEQFLPLIR	LLESKYPRTL	DVVLEEHLKE	IADLKKQELF	HQFVSLSTSG	GKYQFLADSD
490	500	510	520	530	540
TSLMLSLNHP	LAPVRILAMN	HLKKIMKTSK	EGVDESFIKE	AVLARLGDDN	IDVVLSAISA
550	560	570	580	590	600
FEIFKEHFSS	EVTISNLLNL	FQRAELSKNG	EWYEVLKIAA	DILIKEEILS	ENDQLSNQVV
610	620	630	640	650	660
VCLLPFMVIN	NDDTESAEMK	IAIYLSKSGI	CSLHPLLRGW	EEALENVIKS	TKPGKLIGVA
670	680	690	700	710	720
NQKMIELLAD	NINLGDPSSM	LKMVEDLISV	GEEESFNLKQ	KVTFHVILSV	LVSCCSSLKE
730	740	750	760	770	780
THFPFAIRVF	SLLQKKIKKL	ESVITAVEIP	SEWHIELMLD	RGIPVELWAH	YVEELNSTQR
790	800	810	820	830	840
VAVEDSVFLV	FSLKKFIYAL	KAPKSFPKGD	IWWNPEQLKE	DSRDYLHLLI	GLFEMMLNGA
850	860	870	880	890	900
DAVHFRVLMK	LFIKVHLEDV	FQLFKFCSVL	WTYGSSLSNP	LNCSVKTVLQ	TQALYVGCAM
910	920	930	940	950	960
LSSQKTQCKH	QLASISSPVV	TSLLINLGSP	VKEVRRAAIQ	CLQALSGVAS	PFYLIIDHLI
970	980	990	1000	1010	1020
SKAEEITSDA	AYVIQDLATL	FEELQREKKL	KSHQKLSETL	KNLLSCVYSC	PSYIAKDLMK
1030	1040	1050	1060	1070	1080
VLQGVNGEMV	LSQLLPMAEQ	LLEKIQKEPT	AVLKDEAMVL	HLTLGKYNEF	SVSLLNEDPK
1090	1100	1110	1120	1130	1140
SLDIFIKAVH	TTKELYAGMP	TIQITALEKI	TKPFFAAISD	EKVQQKLLRM	LFDLLVNCKN
1150	1160	1170	1180	1190	1200
SHCAQTVSSV	FKGISVNAEQ	VRIELEPPDK	AKPLGTVQQK	RRQKMQQKKS	QDLESVQEVG
1210	1220	1230	1240	1250	1260
GSYWQRVTLI	LELLQHKKKL	RSPQILVPTL	FNLLSRCLEP	LPQEQGNMEY	TKQLILSCLL
1270	1280	1290	1300	1310	1320
NICQKLSPDG	GKIPKDILDE	EKFNVELIVQ	CIRLSEMPQT	HHHALLLLGT	VAGIFPDKVL
1330	1340	1350	1360	1370	1380
HNIMSIFTFM	GANVMRLDDT	YSFQVINKTV	KMVIPALIQS	DSGDSIEVSR	NVEEIVVKII
1390	1400	1410	1420	1430	1440
SVFVDALPHV	PEHRRLPILV	QLVDTLGAEK	FLWILLILLF	EQYVTKTVLA	AAYGEKDAIL
1450	1460	1470	1480	1490	1500
EADTEFWFSV	CCEFSVQHQI	QSLMNILQYL	LKLPEEKEET	IPKAVSFNKS	ESQEEMLQVF
1510	1520	1530	1540	1550	1560
NVETHTSKQL	RHFKFLSVSF	MSQLLSSNNF	LKKVVESGGP	EILKGLEERL	LETVLGYISA
1570	1580	1590	1600	1610	1620
VAQSMERNAD	KLTVKFWRAL	LSKAYDLLDK	VNALLPTETF	IPVIRGLVGN	PLPSVRRKAL
1630	1640	1650	1660	1670	1680
DLLNNKLQQN	ISWKKTIVTR	FLKLVPDLLA	IVQRKKKEGE	EEQAINRQTA	LYTLKLLCKN
1690	1700	1710	1720	1730	1740
FGAENPDPFV	PVLNTAVKLI	APERKEEKNV	LGSALLCIAE	VTSTLEALAI	PQLPSLMPSL
1750	1760	1770	1780	1790	1800
LTTMKNTSEL	VSSEVYLLSA	LAALQKVVET	LPHFISPYLE	GILSQVIHLE	KITSEMGSAS
1810	1820	1830	1840	1850	1860
QANIRLTSLK	KTLATTLAPR	VLLPAIKKTY	KQIEKNWKNH	MGPFMSILQE	HIGVMKKEEL
1870	1880	1890	1900	1910	1920
TSHQSQLTAF	FLEALDFRAQ	HSENDLEEVG	KTENCIIDCL	VAMVVKLSEV	TFRPLFFKLF
1930	1940	1950	1960	1970	1980
DWAKTEDAPK	DRLLTFYNLA	DCIAEKLKGL	FTLFAGHLVK	PFADTLNQVN	ISKTDEAFFD
1990	2000	2010	2020	2030	2040
SENDPEKCCL	LLQFILNCLY	KIFLFDTQHF	ISKERAEALM	MPLVDQLENR	LGGEEKFQER
2050	2060	2070	2080	2090	2100
VTKHLIPCIA	QFSVAMADDS	LWKPLNYQIL	LKTRDSSPKV	RFAALITVLA	LAEKLKENYI
2110	2120	2130	2140
VLLPESIPFL	AELMEDECEE	VEHQCQKTIQ	QLETVLGEPL	QSYF