Q9GMS5

PR
Gene name
IMPG1 (MLGAPC)
Protein name
Interphotoreceptor matrix proteoglycan 1
Names
Mucin-like glycoprotein associated with photoreceptor cells, Sialoprotein associated with cones and rods
Species
Bos taurus (Bovine)
KEGG Pathway
bta:281866
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

272-381 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9GMS5

Entry ID Method Resolution Chain Position Source
AF-Q9GMS5-F1 Predicted AlphaFoldDB

No variants for Q9GMS5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9GMS5

No associated diseases with Q9GMS5

2 regional properties for Q9GMS5

Type Name Position InterPro Accession
domain SEA domain 236 - 357 IPR000082-1
domain SEA domain 572 - 697 IPR000082-2

Functions

Description
EC Number
Subcellular Localization
  • Cell projection, cilium, photoreceptor outer segment
  • Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix
  • Photoreceptor inner segment
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
interphotoreceptor matrix A specialized extracellularc matrix that surrounds the photoreceptors of the retina and lies between them and the apical surface of the retinal pigment epithelium. The IPM has been implicated in several important activities required for photoreceptor function and maintenance.
photoreceptor inner segment The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
photoreceptor outer segment The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.

3 GO annotations of molecular function

Name Definition
chondroitin sulfate binding Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).
heparin binding Binding to heparin, a member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
hyaluronic acid binding Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.

1 GO annotations of biological process

Name Definition
visual perception The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHLEAARVIF FLWIFLQVQG IKDLSIKIYG SEIKDIDNAP RTEATKNTAK TYKVSTMRRI
70 80 90 100 110 120
FDLAKHRTKR SAFFPTGVKV CPQESMEQIL ASLQAYYRLR VCQEAVWEAY RIFLDRLPEP
130 140 150 160 170 180
GEYQDWVSVC QQETFCLFDI GKNFSNSQEH LDLLQQRMKQ RNFLERKDEV VTKETLGELG
190 200 210 220 230 240
QTPGLQQTLP VSHPGPCLSL PMTTAQRNPQ LHPSRTPRVP TRERKIEFTD AAEDALEQKV
250 260 270 280 290 300
ELSISLANQK FKSELDNSQS PYYLEVAAKS QLQMQKIFKK LPGFKEIHVS GFRPKKERDG
310 320 330 340 350 360
TSSTEMQLTA IFKKGKAEAK SPASDPLSLD SNKIESEGDP RGTTEEEKQR ELYPTASELR
370 380 390 400 410 420
KLISRALEED QSLDVGTIQF TDEIVGSLPS LDPDTQLVLP TLLTDITKDA TLSPELPLGQ
430 440 450 460 470 480
PRLETVDRAG HSPPGASPTD GWSPPAMTST SLSETLPFFT ASSVFPQTDQ SATDIMSIDQ
490 500 510 520 530 540
TVLIPRLTVP TDDYSAISPL VPEISHLPTS SEDWLSTSSQ DTMEYLDGVD LTKTPTSSEG
550 560 570 580 590 600
PRNSVGMFPA WIIFLENITP DPGLRYITTS AMTVAARGRE LVVFFSLRVA NVPFSTDLFN
610 620 630 640 650 660
KSSLEYQALE QRFTQLLVPN LRSNLTGFKQ LEILNFRNGS VIVNSKVRFA KSVPYNLTKA
670 680 690 700 710 720
VRGVLEDFRS TAAQQLDLEI DSYSLDVEPA DQADPCKFLA CGEFAQCVRN EWTEEAECRC
730 740 750 760 770 780
RSGTQALVLP IEDCEDIPGK GTPCRSLDQS KNQVYEPGVK KFQRQQDNKV TMKRKFELLT
790
IGYEEFNYQD WEGN