Q9GMF1

PR
Gene name
DGAT1 (DGAT)
Protein name
Diacylglycerol O-acyltransferase 1
Names
CD159 antigen-like family member C, NK cell receptor C, NKG2-C-activating NK receptor, Acyl-CoA retinol O-fatty-acyltransferase, ARAT, Retinol O-fatty-acyltransferase, Diglyceride acyltransferase
Species
Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
KEGG Pathway
EC number
2.3.1.20: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-111 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9GMF1

Entry ID Method Resolution Chain Position Source
AF-Q9GMF1-F1 Predicted AlphaFoldDB

No variants for Q9GMF1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9GMF1

No associated diseases with Q9GMF1

No regional properties for Q9GMF1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9GMF1

Functions

Description
EC Number 2.3.1.20 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
diacylglycerol O-acyltransferase activity Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.
retinol O-fatty-acyltransferase activity Catalysis of the reaction: acyl-CoA + retinol = CoA + retinyl ester.

3 GO annotations of biological process

Name Definition
diacylglycerol metabolic process The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.
monoacylglycerol biosynthetic process The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
triglyceride biosynthetic process The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGDRGGAGGT RRRRTGSRPS SHGGGGPAAA EEEVRDAAAG PDMGAAGDAP APAPSKDADD
70 80 90 100 110 120
GVASGHWELR CHRLQDSLFS SDSGFNNYRG ILNWCVVMLI LSNARLFLEN LIKYGILVDP
130 140 150 160 170 180
IQVVSLFLKD PYSWPAPCLV IAANVFAVAA FQVEKRLAVG ALTEQAGLLL HVANLATILC
190 200 210 220 230 240
FPAAVVLLVE SITPVGSLLA LMVHTILFLK LFSYRDVNLW CRRARAKAAS AGKRASSAAA
250 260 270 280 290 300
PHTVSYPDNL TYRDLYYFLF APTLCYELNF PRSPRIRKRF LLRRILEMLF FTQLQVGLIQ
310 320 330 340 350 360
QWMVPTIQNS MKPFKDMDYS RIIERLLKLA VPNHLIWLIF FYWLFHSCLN AVAELMQFGD
370 380 390 400 410 420
REFYRDWWNS ESVTYFWQNW NIPVHKWCIR HFYKPMLRRG SSRWMARIGV FLASAFFHEY
430 440 450 460 470 480
LVSVPLRMFR LWAFTGMMAQ IPLAWFVGRF FQGNYGNAAV WLTLIIGQPI AVLMYVHDYY
490
VLNYEAPVAG A