Q9GM01

PR
Gene name
GALNT9 (QnpA-13140)
Protein name
Polypeptide N-acetylgalactosaminyltransferase 9
Names
Polypeptide GalNAc transferase 9, GalNAc-T9, pp-GaNTase 9, Protein-UDP acetylgalactosaminyltransferase 9, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
KEGG Pathway
EC number
2.4.1.41: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

15-135 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9GM01

Entry ID Method Resolution Chain Position Source
AF-Q9GM01-F1 Predicted AlphaFoldDB

No variants for Q9GM01

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9GM01

No associated diseases with Q9GM01

3 regional properties for Q9GM01

Type Name Position InterPro Accession
domain Ricin B, lectin domain 468 - 598 IPR000772
domain Glycosyltransferase 2-like 157 - 302 IPR001173
domain N-acetylgalactosaminyltransferase 157 - 456 IPR045885

Functions

Description
EC Number 2.4.1.41 Hexosyltransferases
Subcellular Localization
  • Golgi apparatus membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

3 GO annotations of molecular function

Name Definition
carbohydrate binding Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
metal ion binding Binding to a metal ion.
polypeptide N-acetylgalactosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.

1 GO annotations of biological process

Name Definition
protein O-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAVARKIRTL LTVNILVFVG IVLFSVYCRL QGRSQELVRP LSGGCRPRPA TPAPGSPLRS
70 80 90 100 110 120
GGPRAVVAGR AELVLKGQLP AEPCSPGRLM VPEAEAEAQG GLAATLRDDG QEAEGKYEEY
130 140 150 160 170 180
GYNAQLSDRI SLDRSIPDYR PRKCRHMSYA QDLPQVSVVF IFVNEALSVI LRSVHSVVNH
190 200 210 220 230 240
TPSQLLKEVI LVDDNSDNVE LKFNLDQYVN KRYPGLVKIV RNSRREGLIR ARLQGWKAAT
250 260 270 280 290 300
APVVGFFDAH VEFNTGWAEP ALSRIREDRR RIVLPAIDNI KYSTFEVQQY ANAAHGYNWG
310 320 330 340 350 360
LWCMYIIPPQ DWLDRGDESA PIRTPAMIGC SFVVDREYFG DIGLLDPGME VYGGENVELG
370 380 390 400 410 420
MRVWQCGGSM EVLPCSRVAH IERTRKPYNN DIDYYAKRNA LRAAEVWMDD FKSHVYMAWN
430 440 450 460 470 480
IPMTNPGVDF GDVSERLALR QRLKCRSFKW YLENVYPEMR IYNNTLTYGE VRNSKASGYC
490 500 510 520 530 540
LDQGAEDGDR AILYPCHGMS SQLVRYSADG LLQLGPLGST AFLPDSKCLV DDGRGRTPTL
550 560 570 580 590 600
RKCEDVARPT QRLWDFTQSG PIVSRATGRC LEVEMSKDAN FGLRLVVQRC SGQKWMIRNW
IKHARH