Q9GKK3

PR
Gene name
CSN2
Protein name
Beta-casein
Names
Species
Equus caballus (Horse)
KEGG Pathway
ecb:100033903
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-104 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9GKK3

Entry ID Method Resolution Chain Position Source
AF-Q9GKK3-F1 Predicted AlphaFoldDB

8 variants for Q9GKK3

Variant ID(s) Position Change Description Diseaes Association Provenance
rs1142673303 6 L>F No EVA
rs1138574072 31 L>F No EVA
rs3440767245 45 T>I No EVA
rs3440966821 58 E>V No EVA
rs3443982552 93 V>I No EVA
rs397033886 160 L>P No EVA
rs3439337176 179 P>T No EVA
rs3444076519 213 L>M No EVA

No associated diseases with Q9GKK3

1 regional properties for Q9GKK3

Type Name Position InterPro Accession
conserved_site Casein alpha/beta, conserved site 8 - 15 IPR031305

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

1 GO annotations of molecular function

Name Definition
cysteine-type endopeptidase inhibitor activity Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.

2 GO annotations of biological process

Name Definition
lactation The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young.
negative regulation of cysteine-type endopeptidase activity Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKILILACLV ALALAREKEE LNVSSETVES LSSNEPDSSS EESITHINKE KLQKFKHEGQ
70 80 90 100 110 120
QQREVERQDK ISRFVQPQPV VYPYAEPVPY AVVPQSILPL AQPPILPFLQ PEIMEVSQAK
130 140 150 160 170 180
ETILPKRKVM PFLKSPIVPF SERQILNPTN GENLRLPVHL IQPFMHQVPQ SLLQTLMLPS
190 200 210 220 230 240
QPVLSPPQSK VAPFPQPVVP YPQRDTPVQA FLLYQDPRLG PTGELDPATQ PIVAVHNPVI
V