Q9FZN8
Gene name |
TCS1 |
Protein name |
3,7-dimethylxanthine N-methyltransferase TCS1 |
Names |
TCS1a, Caffeine synthase 1 |
Species |
Camellia sinensis (Tea) |
KEGG Pathway |
ag:BAB12278 |
EC number |
2.1.1.160: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FZN8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FZN8-F1 | Predicted | AlphaFoldDB |
No variants for Q9FZN8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9FZN8 | |||||
No associated diseases with Q9FZN8
No regional properties for Q9FZN8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9FZN8 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.160 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| paraxanthine:S-adenosyl-L-methionine 3-N-methyltransferase activity | Catalysis of the reaction: 1,7-dimethylxanthine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine. |
| theobromine:S-adenosyl-L-methionine 1-N-methyltransferase activity | Catalysis of the reaction: theobromine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| alkaloid metabolic process | The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases). |
| methylation | The process in which a methyl group is covalently attached to a molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MELATAGKVN | EVLFMNRGEG | ESSYAQNSSF | TQQVASMAQP | ALENAVETLF | SRDFHLQALN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AADLGCAAGP | NTFAVISTIK | RMMEKKCREL | NCQTLELQVY | LNDLFGNDFN | TLFKGLSSEV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IGNKCEEVPC | YVMGVPGSFH | GRLFPRNSLH | LVHSSYSVHW | LTQAPKGLTS | REGLALNKGK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IYISKTSPPV | VREAYLSQFH | EDFTMFLNAR | SQEVVPNGCM | VLILRGRQCS | DPSDMQSCFT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| WELLAMAIAE | LVSQGLIDED | KLDTFNIPSY | FASLEEVKDI | VERDGSFTID | HIEGFDLDSV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EMQENDKWVR | GEKFTKVVRA | FTEPIISNQF | GPEIMDKLYD | KFTHIVVSDL | EAKLPKTTSI |
| ILVLSKIDG |