Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9FKG2

Entry ID Method Resolution Chain Position Source
AF-Q9FKG2-F1 Predicted AlphaFoldDB

13 variants for Q9FKG2

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH07462246 8 S>P No 1000Genomes
tmp_5_24765219_G_C 14 Q>E No 1000Genomes
tmp_5_24765159_C_G 34 D>H No 1000Genomes
tmp_5_24765126_G_C 45 L>V No 1000Genomes
ENSVATH12896939 52 P>L No 1000Genomes
ENSVATH03462065 73 M>R No 1000Genomes
ENSVATH03462064 82 S>T No 1000Genomes
tmp_5_24765012_T_C 83 T>A No 1000Genomes
ENSVATH07462244 92 V>L No 1000Genomes
tmp_5_24764847_C_A 138 E>* No 1000Genomes
tmp_5_24764846_T_A 138 E>V No 1000Genomes
ENSVATH00746856 185 V>L No 1000Genomes
ENSVATH07462243 192 T>A No 1000Genomes

No associated diseases with Q9FKG2

1 regional properties for Q9FKG2

Type Name Position InterPro Accession
domain AP2/ERF domain 106 - 170 IPR001471

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

5 GO annotations of biological process

Name Definition
ethylene-activated signaling pathway The series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.
glucosinolate metabolic process The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.
negative regulation of wax biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of wax biosynthetic process.
positive regulation of DNA-templated transcription Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
response to water deprivation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9LY05 ERF106 Ethylene-responsive transcription factor ERF106 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
METFEESSDL DVIQKHLFED LMIPDGFIED FVFDDTAFVS GLWSLEPFNP VPKLEPSSPV
70 80 90 100 110 120
LDPDSYVQEI LQMEAESSSS SSTTTSPEVE TVSNRKKTKR FEETRHYRGV RRRPWGKFAA
130 140 150 160 170 180
EIRDPAKKGS RIWLGTFESD IDAARAYDYA AFKLRGRKAV LNFPLDAGKY DAPVNSCRKR
190 200
RRTDVPQPQG TTTSTSSSSS N