Q9FJG2
PR
Gene name |
At5g18000 (MCM23.7) |
Protein name |
B3 domain-containing protein At5g18000 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G18000 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FJG2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FJG2-F1 | Predicted | AlphaFoldDB |
45 variants for Q9FJG2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_5961469_A_T | 2 | V>E | No | 1000Genomes | |
| ENSVATH06986155 | 4 | N>K | No | 1000Genomes | |
| tmp_5_5961449_C_A | 9 | G>C | No | 1000Genomes | |
| tmp_5_5961442_A_G | 11 | I>T | No | 1000Genomes | |
| ENSVATH03072387 | 12 | M>I | No | 1000Genomes | |
| tmp_5_5961400_C_G | 25 | R>P | No | 1000Genomes | |
| tmp_5_5961397_C_A | 26 | R>M | No | 1000Genomes | |
| ENSVATH00628838 | 44 | S>R | No | 1000Genomes | |
| ENSVATH06986146 | 50 | S>L | No | 1000Genomes | |
| tmp_5_5961018_C_T | 57 | R>K | No | 1000Genomes | |
| tmp_5_5961016_C_A | 58 | V>L | No | 1000Genomes | |
| ENSVATH06986144 | 62 | R>S | No | 1000Genomes | |
| ENSVATH06986143 | 65 | Q>H | No | 1000Genomes | |
| ENSVATH06986142 | 72 | P>T | No | 1000Genomes | |
| ENSVATH06986141 | 105 | M>L | No | 1000Genomes | |
| ENSVATH06986140 | 110 | T>S | No | 1000Genomes | |
| ENSVATH06986137 | 127 | T>I | No | 1000Genomes | |
| ENSVATH06986138 | 127 | T>P | No | 1000Genomes | |
| ENSVATH10821937 | 129 | S>C | No | 1000Genomes | |
| ENSVATH06986136 | 129 | S>N | No | 1000Genomes | |
| tmp_5_5960693_C_T | 131 | G>D | No | 1000Genomes | |
| tmp_5_5960677_T_G | 136 | E>D | No | 1000Genomes | |
| ENSVATH06986132 | 139 | K>N | No | 1000Genomes | |
| ENSVATH14072396 | 152 | E>D | No | 1000Genomes | |
| ENSVATH10821877 | 165 | A>T | No | 1000Genomes | |
| tmp_5_5960564_T_G | 174 | Q>P | No | 1000Genomes | |
| ENSVATH10821876 | 193 | T>R | No | 1000Genomes | |
| ENSVATH14072395 | 200 | E>* | No | 1000Genomes | |
| ENSVATH06986129 | 203 | S>N | No | 1000Genomes | |
| ENSVATH06986128 | 205 | D>Y | No | 1000Genomes | |
| ENSVATH06986126 | 214 | I>V | No | 1000Genomes | |
| ENSVATH06986119 | 237 | D>G | No | 1000Genomes | |
| tmp_5_5960280_G_T | 239 | H>N | No | 1000Genomes | |
| ENSVATH06986118 | 242 | T>S | No | 1000Genomes | |
| ENSVATH06986117 | 244 | T>I | No | 1000Genomes | |
| ENSVATH03072378 | 245 | T>M | No | 1000Genomes | |
| ENSVATH00628833 | 251 | Y>H | No | 1000Genomes | |
| ENSVATH06986115 | 255 | K>R | No | 1000Genomes | |
| ENSVATH10821875 | 272 | S>Y | No | 1000Genomes | |
| ENSVATH06986114 | 273 | G>C | No | 1000Genomes | |
| ENSVATH00628832 | 285 | L>V | No | 1000Genomes | |
| tmp_5_5960139_C_T | 286 | V>I | No | 1000Genomes | |
| ENSVATH14072154 | 291 | T>M | No | 1000Genomes | |
| ENSVATH06986111 | 298 | T>K | No | 1000Genomes | |
| ENSVATH10821813 | 305 | S>C | No | 1000Genomes |
No associated diseases with Q9FJG2
1 regional properties for Q9FJG2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Sugar phosphate transporter domain | 74 - 368 | IPR004853 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| protein heterodimerization activity | Binding to a nonidentical protein to form a heterodimer. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| double fertilization forming a zygote and endosperm | Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana. |
| embryo sac development | The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate. |
| synergid death | Synergid cells undergo degeneration and death in response to penetration by the pollen tube. It is an active process that involves a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9LXE1 | REM23 | B3 domain-containing protein REM23 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FK61 | At5g18090 | B3 domain-containing protein At5g18090 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q5BPT7 | At2g16210 | B3 domain-containing protein At2g16210 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q680D9 | At5g25475 | B3 domain-containing protein At5g25475 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVKNKAFFGQ | IMEERDNPAF | FKILRREDHS | TEMMRMIPHH | LIRSISDKSS | SFKMVLRVPW |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GRSWQVKISK | NPNFHYMEDR | GWNQFVNDNG | LGENEYLTFT | HEANMCFNVT | IFEADGTEML |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RPRKTITSSS | GRNKREERKS | IYKDVKKEEE | IESWSESSHP | CHKTAESTSG | RLTQKQELNL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RKKEADKTEK | SKTSKKKKVE | TVSNDSEAGT | SSLIPEFKLT | IKKSHLLFLG | IPKKFVDMHM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PTETTMFKIH | YPRGKKSWDV | TYVVTDVQSR | FSGGWSRLAK | ELGLLVGDVC | TFKLIKPTEM |
| RVKVSKE |