Q9FI78

PR
Gene name
HST
Protein name
Shikimate O-hydroxycinnamoyltransferase
Names
Hydroxycinnamoyl transferase, AtHCT, Hydroxycinnamoyl-Coenzyme A shikimate/quinate hydroxycinnamoyltransferase
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G48930
EC number
2.3.1.133: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

164-248 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

4 structures for Q9FI78

Entry ID Method Resolution Chain Position Source
5KJS X-ray 220 A A 1-433 PDB
5KJT X-ray 250 A A 1-433 PDB
5KJU X-ray 244 A A 1-433 PDB
AF-Q9FI78-F1 Predicted AlphaFoldDB

9 variants for Q9FI78

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_19837896_G_C 66 P>R No 1000Genomes
ENSVATH07376448 95 V>L No 1000Genomes
ENSVATH00721060 125 A>T No 1000Genomes
tmp_5_19837387_G_C 190 A>G No 1000Genomes
ENSVATH07376432 234 Q>E No 1000Genomes
ENSVATH14614509 312 G>E No 1000Genomes
tmp_5_19837000_G_A 319 T>I No 1000Genomes
ENSVATH14614508 321 Y>S No 1000Genomes
ENSVATH00721054 362 K>R No 1000Genomes

No associated diseases with Q9FI78

No regional properties for Q9FI78

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9FI78

Functions

Description
EC Number 2.3.1.133 Transferring groups other than amino-acyl groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

3 GO annotations of molecular function

Name Definition
acyltransferase activity, transferring groups other than amino-acyl groups Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
quinate O-hydroxycinnamoyltransferase activity Catalysis of the reaction: feruloyl-CoA + quinate = O-feruloylquinate + CoA.
shikimate O-hydroxycinnamoyltransferase activity Catalysis of the reaction: shikimate + coumaroyl-CoA = 4-coumaroylshikimate + CoA.

4 GO annotations of biological process

Name Definition
auxin homeostasis A homeostatic process that maintains an endogenous steady-state concentration of primary auxin, or constant level of auxin in a biological system, by a number of biochemical processes including transport, biosynthesis, catabolism and conjugation.
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
lignin biosynthetic process The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers.
positive regulation of flavonoid biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKINIRDSTM VRPATETPIT NLWNSNVDLV IPRFHTPSVY FYRPTGASNF FDPQVMKEAL
70 80 90 100 110 120
SKALVPFYPM AGRLKRDDDG RIEIDCNGAG VLFVVADTPS VIDDFGDFAP TLNLRQLIPE
130 140 150 160 170 180
VDHSAGIHSF PLLVLQVTFF KCGGASLGVG MQHHAADGFS GLHFINTWSD MARGLDLTIP
190 200 210 220 230 240
PFIDRTLLRA RDPPQPAFHH VEYQPAPSMK IPLDPSKSGP ENTTVSIFKL TRDQLVALKA
250 260 270 280 290 300
KSKEDGNTVS YSSYEMLAGH VWRSVGKARG LPNDQETKLY IATDGRSRLR PQLPPGYFGN
310 320 330 340 350 360
VIFTATPLAV AGDLLSKPTW YAAGQIHDFL VRMDDNYLRS ALDYLEMQPD LSALVRGAHT
370 380 390 400 410 420
YKCPNLGITS WVRLPIYDAD FGWGRPIFMG PGGIPYEGLS FVLPSPTNDG SLSVAIALQS
430
EHMKLFEKFL FEI