Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9FHK0

Entry ID Method Resolution Chain Position Source
AF-Q9FHK0-F1 Predicted AlphaFoldDB

23 variants for Q9FHK0

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH03361199 21 S>A No 1000Genomes
tmp_5_18386242_T_G 38 I>L No 1000Genomes
ENSVATH07343423 45 A>P No 1000Genomes
ENSVATH07343422 49 D>N No 1000Genomes
ENSVATH07343421 56 G>V No 1000Genomes
ENSVATH03361163 58 K>E No 1000Genomes
ENSVATH12548138 62 D>V No 1000Genomes
ENSVATH07343420 69 G>E No 1000Genomes
tmp_5_18386140_T_C 72 T>A No 1000Genomes
ENSVATH12548135 96 L>F No 1000Genomes
ENSVATH07343413 96 L>S No 1000Genomes
tmp_5_18385973_A_T 100 F>Y No 1000Genomes
ENSVATH07343411 103 F>Y No 1000Genomes
ENSVATH00710789 171 A>V No 1000Genomes
ENSVATH07343407 176 Q>E No 1000Genomes
ENSVATH07343403 194 L>I No 1000Genomes
tmp_5_18385314_T_A 204 K>M No 1000Genomes
tmp_5_18385261_C_T 222 D>N No 1000Genomes
tmp_5_18385258_C_T 223 D>N No 1000Genomes
tmp_5_18385222_C_T 235 V>I No 1000Genomes
ENSVATH12548080 269 E>D No 1000Genomes
tmp_5_18384840_T_A 298 E>D No 1000Genomes
ENSVATH00710781 307 Q>L No 1000Genomes

No associated diseases with Q9FHK0

1 regional properties for Q9FHK0

Type Name Position InterPro Accession
domain F-box domain 68 - 116 IPR001810

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
protein ubiquitination The process in which one or more ubiquitin groups are added to a protein.
regulation of apoptotic process Any process that modulates the occurrence or rate of cell death by apoptotic process.
ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9UK96 FBXO10 F-box only protein 10 Homo sapiens (Human) PR
Q7TQF2 Fbxo10 F-box only protein 10 Mus musculus (Mouse) PR
10 20 30 40 50 60
MSVSDEEDEC FARFLESEVS SVEDKEETKE PEAKRQRIEK GETKALEKDE DQKENGNKDK
70 80 90 100 110 120
TDAKRIESGV FTNVPTELFR HILKFLSSED LVSCSLVCKF LNFAAADESL WRRLYCIRWG
130 140 150 160 170 180
LTLPSRKLRE SAWKKLYIDR DEQDMIELVR TCPSDFKEYY VHMQAAKRSQ APLPSQMVDD
190 200 210 220 230 240
RIILDNTVLE QVSLWKKSKG LTDKAVTGHI CLGTKCSYHQ IDDVFICKET GNVHVCDDNC
250 260 270 280 290 300
KEVILSPEGD LMVCTISGVC SDTLLVQTEP DADGCYEEEA ELEAEVFTDK SRLARAFELG
310
YNCDDEQELE RTLRFC