Q9FD10

PR
Gene name
sseJ (STM1631)
Protein name
Secreted effector protein SseJ
Names
Salmonella-translocated effector J, STE J
Species
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
KEGG Pathway
stm:STM1631
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-47 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9FD10

Entry ID Method Resolution Chain Position Source
AF-Q9FD10-F1 Predicted AlphaFoldDB

No variants for Q9FD10

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9FD10

No associated diseases with Q9FD10

No regional properties for Q9FD10

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9FD10

Functions

Description
EC Number
Subcellular Localization
  • Secreted
  • Host cytoplasm
  • Secreted via type III secretion system 2 (SPI-2 T3SS), and delivered into the host cytoplasm
  • Localizes to the Salmonella-containing vacuole (SCV) at early time points following invasion and subsequently traffics away from the SCV along Salmonella-induced filaments (Sifs) in epithelial cells
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
host cell endosome A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to host cell lysosomes for degradation.
host cell membrane Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.

4 GO annotations of molecular function

Name Definition
cholesterol O-acyltransferase activity Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA.
glycerophospholipid acyltransferase (CoA-dependent) activity Catalysis of the reaction: 1-radyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-radyl-2-acyl-sn-glycero-3-phosphocholine = 1-radyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acyl-sn-glycero-3-phosphoethanolamine.
lipase activity Catalysis of the hydrolysis of a lipid or phospholipid.
small GTPase binding Binding to a small monomeric GTPase.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPLSVGQGYF TSSISSEKFN AIKESARLPE LSLWEKIKAY FFTTHHAEAL ECIFNLYHHQ
70 80 90 100 110 120
ELNLTPVQVR GAYIKLRALA SQGCKEQFII ESQEHADKLI IKDDNGENIL SIEVECHPEA
130 140 150 160 170 180
FGLAKEINKS HPKPKNISLG DITRLVFFGD SLSDSLGRMF EKTHHILPSY GQYFGGRFTN
190 200 210 220 230 240
GFTWTEFLSS PHFLGKEMLN FAEGGSTSAS YSCFNCIGDF VSNTDRQVAS YTPSHQDLAI
250 260 270 280 290 300
FLLGANDYMT LHKDNVIMVV EQQIDDIEKI ISGGVNNVLV MGIPDLSLTP YGKHSDEKRK
310 320 330 340 350 360
LKDESIAHNA LLKTNVEELK EKYPQHKICY YETADAFKVI MEAASNIGYD TENPYTHHGY
370 380 390 400
VHVPGAKDPQ LDICPQYVFN DLVHPTQEVH HCFAIMLESF IAHHYSTE