Q9F5P3
Gene name |
gadA (lmo0447) |
Protein name |
Glutamate decarboxylase alpha |
Names |
GAD-alpha |
Species |
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) |
KEGG Pathway |
lmo:lmo0447 |
EC number |
4.1.1.15: Carboxy-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9F5P3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9F5P3-F1 | Predicted | AlphaFoldDB |
No variants for Q9F5P3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9F5P3 | |||||
No associated diseases with Q9F5P3
No regional properties for Q9F5P3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9F5P3 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 4.1.1.15 | Carboxy-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| glutamate decarboxylase activity | Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2. |
| pyridoxal phosphate binding | Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glutamate catabolic process | The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFKTNVEQNN | VPVFGSFESG | QDLPEKRMNK | ESVDPRIAYQ | LVKDQLIDEG | SARQNLATFC |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QTYMEPEAEQ | IMAETMEKNA | IDKSEYPQTA | KLESSCVNML | ADLWNVDESE | HYMGTSTVGS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SEACMLGGMA | MKFRWRSAAL | KNGLDIHAKK | PSLVISSGYQ | VCWEKFCVYW | DIELREVPMS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EEHLSINTDI | IMDYVDEYTI | GIVGILGITY | TGKFDDIMTL | NDLVEDYNNT | HDNEVVIHVD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GASGAMFTPF | VEPGLEWDFR | LPNVVSINTS | GHKYGLVYPG | VGWILWRDKE | YLPEELVFDV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SYLGGHMPTM | AINFSRSASQ | IIGQYYNFLR | FGYEGYRQIH | MRTRDGALQL | SQAVAETGLF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EIYNDGANLP | IVCYKLKDDA | NVAWTLYDLA | DRLQMKGWQV | PAYPLPKEMG | NTIIQRYVCR |
| 430 | 440 | 450 | 460 | ||
| GDLGQNMVTA | FKNDLSESIE | ELNNAHILYH | DVNTSKTHGF | TH |