Q9F5K5

PR
Gene name
aviRa
Protein name
23S rRNA (guanine(2535)-N(1))-methyltransferase
Names
Avilamycin resistance protein A
Species
Streptomyces viridochromogenes
KEGG Pathway
ag:AAG32067
EC number
2.1.1.209: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

50-233 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for Q9F5K5

Entry ID Method Resolution Chain Position Source
1O9G X-ray 150 A A 1-250 PDB
1O9H X-ray 240 A A 1-250 PDB
AF-Q9F5K5-F1 Predicted AlphaFoldDB

No variants for Q9F5K5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9F5K5

No associated diseases with Q9F5K5

4 regional properties for Q9F5K5

Type Name Position InterPro Accession
domain Protein kinase domain 140 - 390 IPR000719
active_site Serine/threonine-protein kinase, active site 259 - 271 IPR008271
binding_site Protein kinase, ATP binding site 146 - 169 IPR017441
domain Aurora kinase A 134 - 391 IPR030611

Functions

Description
EC Number 2.1.1.209 Methyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
rRNA (guanine-N1-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N1-methylguanine.

3 GO annotations of biological process

Name Definition
methylation The process in which a methyl group is covalently attached to a molecule.
response to antibiotic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
rRNA methylation The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSAYRHAVER IDSSDLACGV VLHSAPGYPA FPVRLATEIF QRALARLPGD GPVTLWDPCC
70 80 90 100 110 120
GSGYLLTVLG LLHRRSLRQV IASDVDPAPL ELAAKNLALL SPAGLTAREL ERREQSERFG
130 140 150 160 170 180
KPSYLEAAQA ARRLRERLTA EGGALPCAIR TADVFDPRAL SAVLAGSAPD VVLTDLPYGE
190 200 210 220 230 240
RTHWEGQVPA QPVAGLLRSL ASALPAHAVI AVTDRSRKIP VAPVKALERL KIGTRSAVLV
RAADVLEAGP