Q9F364

PR
Gene name
nadA
Protein name
Quinolinate synthase
Names
Species
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
KEGG Pathway
sco:SCO2162
EC number
2.5.1.72: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-79 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9F364

Entry ID Method Resolution Chain Position Source
AF-Q9F364-F1 Predicted AlphaFoldDB

No variants for Q9F364

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9F364

No associated diseases with Q9F364

No regional properties for Q9F364

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9F364

Functions

Description
EC Number 2.5.1.72 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
metal ion binding Binding to a metal ion.
quinolinate synthetase A activity Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate.

1 GO annotations of biological process

Name Definition
'de novo' NAD biosynthetic process from aspartate The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTTAQTQELD VQPTPLALLL LGREADPRSE RGVECPGDLP SPSDPDLVAR ARAAKEKLGD
70 80 90 100 110 120
KVFVLGHHYQ RDEVIQFADV TGDSFKLARD AAARPEAEYI VFCGVHFMAE SADILTSNDQ
130 140 150 160 170 180
KVVLPDLAAG CSMADMATAE QVAECWDVLT EAGIAEQVVP VSYMNSSADI KAFTGKHGGT
190 200 210 220 230 240
ICTSSNAERA LNWAFEQGEK VLFLPDQHLG RNTAVRDLGM SLEDCVVYNP HRPNGGLTAK
250 260 270 280 290 300
ELRDANMILW RGHCSVHGRF SLDSVNDVRE RIPGVNVLVH PECKHEVVAA ADYVGSTEYI
310 320 330 340 350 360
IKALEAAPAG SKWAIGTELN LVRRLANRFA AEDKEIVFLD KTVCFCSTMN RIDLPHLVWT
370 380 390
LESLAEGTLV NRIEVDQETE AFAKLALERM LALP