Q9EQR2

PR
Gene name
Agps (Ads)
Protein name
Alkyldihydroxyacetonephosphate synthase, peroxisomal
Names
Alkyl-DHAP synthase, Alkylglycerone-phosphate synthase
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:84114
EC number
2.5.1.26: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-174 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9EQR2

Entry ID Method Resolution Chain Position Source
AF-Q9EQR2-F1 Predicted AlphaFoldDB

No variants for Q9EQR2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9EQR2

No associated diseases with Q9EQR2

No regional properties for Q9EQR2

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9EQR2

Functions

Description
EC Number 2.5.1.26 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Peroxisome membrane
  • Peroxisome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
peroxisomal membrane The lipid bilayer surrounding a peroxisome.
peroxisome A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.

2 GO annotations of molecular function

Name Definition
alkylglycerone-phosphate synthase activity Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion.
FAD binding Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.

2 GO annotations of biological process

Name Definition
ether lipid biosynthetic process The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.
lipid biosynthetic process The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O00116 AGPS Alkyldihydroxyacetonephosphate synthase, peroxisomal Homo sapiens (Human) PR
Q8C0I1 Agps Alkyldihydroxyacetonephosphate synthase, peroxisomal Mus musculus (Mouse) PR
10 20 30 40 50 60
MAEAAGEAGA SERDPDAVRA RRRLRVLSGH LLGRPQEAPS TNECKARRAA SAAGASPAAS
70 80 90 100 110 120
PAAPESGTIP KKRQELMKWN GWGYNDSKFL LNKKGQVELT GKRYPLSGLA LPTLKDWIQN
130 140 150 160 170 180
TLGVNLEHKT TSKPSINPSE APPSIVNEDF LQELKEAHIS YSQDADDRVF RAHGHCLHEI
190 200 210 220 230 240
FLLREGMFER IPDIVVWPTC HDDVVKIVNL ACKYNLCIIP IGGGTSVSYG LMCPADETRT
250 260 270 280 290 300
IISLDTSQMN RILWVDENNL TAHVEAGITG QDLERQLKES GYCTGHEPDS LEFSIVGGWI
310 320 330 340 350 360
STRASGMKKN VYGNIEDLVV HMKMVTPRGV IEKSSQGPRM STGPDIHHFI MGSEGTLGVI
370 380 390 400 410 420
TEATIKIRPT PEYQKYGSVA FPNFEQGVAC LREIAKQRCA PASIRLMDNQ QFQFGHALKP
430 440 450 460 470 480
QVSSIFTSFL DGFKKFYITK FKGFDPNQIS VATLLFEGDR EKVLQHEKQV YDIAAKFGGL
490 500 510 520 530 540
AAGEDNGQRG YLLTYVIAYM RDLGLEYYVV GESFETSAPW DRVIDLCRNV KERIRRECKE
550 560 570 580 590 600
RGVQFAPLST CRVTQTYDAG ACIYFYFAFN YRGISDPLTV FEQTEAAARD EILANGGSLS
610 620 630 640
HHHGVGKLRK QWLKESISDV GFGMLKSVKD YVDPSNIFGN RNLL