Q9DUT3

PR
Gene name
ORF1a
Protein name
Replication protein 1a
Names
Species
Pelargonium zonate spot virus (isolate Tomato/Italy/1982) (PZSV) (Pelargonium zonate spot virus (isolate Tomato))
KEGG Pathway
vg:956568
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

487-590 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q9DUT3

Entry ID Method Resolution Chain Position Source

No variants for Q9DUT3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9DUT3

No associated diseases with Q9DUT3

4 regional properties for Q9DUT3

Type Name Position InterPro Accession
domain Alphavirus-like methyltransferase (MT) domain 71 - 411 IPR002588
domain Replication protein 1a, necrotic phentoype-determining domain 429 - 597 IPR021002
domain Cucumber mosaic virus 1a protein C-terminal 600 - 680 IPR022184
domain (+) RNA virus helicase core domain 667 - 962 IPR027351

Functions

Description
EC Number
Subcellular Localization
  • Host endoplasmic reticulum membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
host cell endoplasmic reticulum membrane The lipid bilayer surrounding the host cell endoplasmic reticulum.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
mRNA methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule.
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAATSFNVRD LINSNGADAM GVRGLVDAHA TKAAEEQFEY IKRSKKVWVR QILSASDGEK
70 80 90 100 110 120
MQKRFGGTFD LQLSKNLCPH SFAGAMRQCE TLECLSSFPE DSLILDFGGS WLFHWQRQHN
130 140 150 160 170 180
VHSCCPVLDA RDMARHQERM ISMQKCVAHR PGKFESFESP DFCLLKAEDC EVQSPYAISI
190 200 210 220 230 240
HGAYDMGFEG LCKAMHSHGT IMLRGTMMFD ANMLVFNEGV MEDLNCRWTK EKGDPYGLRG
250 260 270 280 290 300
APCEDMVHFD FIDESTLSYS HSWKNIKSFL TEGGYQIGNV QYVLERCVIS YGIMSFKIFA
310 320 330 340 350 360
VSGKIPHTRL RHCVWFPKVR DYVNINPSDP RIWSKVRVKL DTVREVEEIC FRCPKDVSKI
370 380 390 400 410 420
EVMGGESETC GIMSVLYSST IIVNGMTMMA GERLDVLDYH HVAFSLMLSA RRKFDMFGKA
430 440 450 460 470 480
MNSLEWKGWV SHFFKSLWPS GDLRDLFGRY FPSLIRYYDK IEFVEKLTHC EVFVNELGMT
490 500 510 520 530 540
DDKEQRDVVA EAADVLKNTL LKVAIKMSLD KTFRPAEEKK EERTTTTTVT SSAVGDVDER
550 560 570 580 590 600
PAGTVSGPTI QAPSVTQENT VTSLSEPLDG RLAVRLEAMK EYKRYLLKLQ KNTESNLAGL
610 620 630 640 650 660
WSLCGGTSDS NNLISTEVLR IMRQSDSLVN LHKADGGWLF PNDFEYMVGY NSSGLGEKRP
670 680 690 700 710 720
NEVFLVNKDC VLNNNVLLAN GVPAQPPKGN INLMDGVAGC GKTTAIKRAF VFESDLIVTA
730 740 750 760 770 780
NKKSSEDILK AMFRDTPDIG RNKVRTADSV LMHGVAHKVK RVLFDEVSLV HFGQLCAILT
790 800 810 820 830 840
ISGAEELIGF GDSEQISFVS RDRLFDMKYH KLSPDSSDQQ IRTFRCPKDV VECVKIMARK
850 860 870 880 890 900
VGARGSKYNN WFTTSAVRKS LGYHKVSSIN ESPLRPDVHY LTMTQADKAS LLSKARETRF
910 920 930 940 950 960
RPSVSTIDEV IKTTHESQGI SVPKVILWRG KSTKCDLFTD KMELRFGCCH QASRKFRLLF
GC