Q9DGM7

PR
Gene name
mvp
Protein name
Major vault protein
Names
MVP
Species
Ictalurus punctatus (Channel catfish) (Silurus punctatus)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

427-501 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9DGM7

Entry ID Method Resolution Chain Position Source
AF-Q9DGM7-F1 Predicted AlphaFoldDB

No variants for Q9DGM7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9DGM7

No associated diseases with Q9DGM7

17 regional properties for Q9DGM7

Type Name Position InterPro Accession
binding_site IQ motif, EF-hand binding site 688 - 717 IPR000048
repeat Major vault protein, N-terminal 69 - 129 IPR002499-1
repeat Major vault protein, N-terminal 130 - 182 IPR002499-2
repeat Major vault protein, N-terminal 183 - 235 IPR002499-3
repeat Major vault protein, N-terminal 236 - 290 IPR002499-4
repeat Major vault protein, N-terminal 292 - 340 IPR002499-5
repeat Major vault protein, N-terminal 341 - 411 IPR002499-6
repeat Major vault protein, N-terminal 412 - 464 IPR002499-7
domain Major vault protein, shoulder domain 534 - 685 IPR021870
domain Major vault protein repeat domain 3 482 - 543 IPR040989
domain Major vault protein repeat domain 2 63 - 122 IPR041134-1
domain Major vault protein repeat domain 2 287 - 333 IPR041134-2
domain Major vault protein repeat domain 4 407 - 466 IPR041136
domain Major vault protein repeat domain 126 - 167 IPR041139-1
domain Major vault protein repeat domain 179 - 219 IPR041139-2
domain Major vault protein repeat domain 233 - 274 IPR041139-3
domain Major vault protein repeat domain 337 - 396 IPR041139-4

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKRPAGSHM EHNDLTDASI IRIPPHHYIH VLDQNTNIAR VEVGPLTYIR QDNERVLFSP
70 80 90 100 110 120
TRMTMVPPRH YCVILNPVAR DDEGHVQFDT AGQAKLRHAD LEIRLTQDPF PLYPGEEIQK
130 140 150 160 170 180
EVTPLQIVYP DTALRLQALL DFEEESGEKR VAGDEWLFEG PGTYIPRKEV AVLEIIKATV
190 200 210 220 230 240
IREHQAIRLR ARKEGVDRSG TRRVTGEEWQ VSKVGAYLPG AHEEVIDIVN AFILTDKRAL
250 260 270 280 290 300
HVRALRPFRD AGGRDRRTGE EWLVTVADRE AHIPSVAEEV VGVVDVTTLN SREYCVILDP
310 320 330 340 350 360
VGPDGKPQLG QKRVVKGERS FFLRPGEHLE NGIQDVYVLS EEEGLVLRAV EAFNDTEAQE
370 380 390 400 410 420
EDEEEEEEEE QAKKTSVQRR PGDRWMLRGP IEYVPPVTVE VMLRRQAIPL DENEGIYVRD
430 440 450 460 470 480
IKTGKVRAVI GHTYMLTHDE ELWEKELPPN VEKLLSTVRD PLADRSEHNQ NAVAEPRDKT
490 500 510 520 530 540
MVVSYRVPHN AAVQVYDYRE KKARVVFGPD LVMLGPDEQF TVLSLSGEKP KRANVIKAIC
550 560 570 580 590 600
LLLGPDFCTD IITIETADHA RLQLQLAYNW HFEVKNHSDP AQAAALFSVP DFVGDACKAI
610 620 630 640 650 660
ASRIRGAVAS VQFDDFHKNS IRIICSAVFG FDEKLAVRSS LRFNQNGLVI SSVDIQSVEP
670 680 690 700 710 720
VDQRTRDALQ KSVQLAIEIT TNSQEATARH EAERLEQEAR GKLERQKITD QAEAERARKE
730 740 750 760 770 780
LLELEALSAA VESTGAAKAE AQSRAEAARI QGEAAVQEAK LKVEALRIEA EAEMVRLAKA
790 800 810 820 830 840
REQELLYKKE LDHLEVEKQQ KLVTIESQRF KQLVEAIGSE TLTAMARAGP ELQVKMLQAL
850 860 870
GLKSTLITDG SSPINLFTTA NGLLGAMKAP E