Q9DA03

PR
Gene name
Lyrm7 (MZM1L)
Protein name
Complex III assembly factor LYRM7
Names
LYR motif-containing protein 7
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:75530
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-84 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9DA03

Entry ID Method Resolution Chain Position Source
AF-Q9DA03-F1 Predicted AlphaFoldDB

3 variants for Q9DA03

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389144683 37 N>Y No EVA
rs3389153603 63 E>D No EVA
rs3389144675 95 P>A No EVA

No associated diseases with Q9DA03

2 regional properties for Q9DA03

Type Name Position InterPro Accession
domain Complex 1 LYR protein domain 6 - 60 IPR008011
domain LYRM7, LYR domain 7 - 77 IPR045298

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
mitochondrial membrane Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

1 GO annotations of molecular function

Name Definition
protein folding chaperone Binding to a protein or a protein-containing complex to assist the protein folding process.

2 GO annotations of biological process

Name Definition
cellular respiration The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).
mitochondrial respiratory chain complex III assembly The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q2M2S9 LYRM7 Complex III assembly factor LYRM7 Bos taurus (Bovine) PR
Q5U5X0 LYRM7 Complex III assembly factor LYRM7 Homo sapiens (Human) PR
B4F7A1 Lyrm7 Complex III assembly factor LYRM7 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MGQPAKVLQL FKTLHRTRQQ VFKNDKRALE AARVKINEEF KKHKNETSPE KIKEMMKLGS
70 80 90 100
DVELLLRTAV IQGIHTDHDT LQLVPRKDLL TENVPYCDAP TQKQ