Q9D9H8

PR
Gene name
Protein name
Mitochondrial protein C2orf69 homolog
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:73467
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-105 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9D9H8

Entry ID Method Resolution Chain Position Source
AF-Q9D9H8-F1 Predicted AlphaFoldDB

30 variants for Q9D9H8

Variant ID(s) Position Change Description Diseaes Association Provenance
rs246586703 30 L>P No EVA
rs581034641 73 R>W No EVA
rs3388471627 97 I>S No EVA
rs585916858 109 N>S No EVA
rs3388469194 136 M>T No EVA
rs222525685 142 S>T No EVA
rs3388470726 150 S>N No EVA
rs3388471531 174 N>K No EVA
rs579536229 189 S>N No EVA
rs582070285 192 N>S No EVA
rs3388471082 201 E>K No EVA
rs3388470725 219 E>G No EVA
rs3388471005 221 V>A No EVA
rs254716616 229 P>A No EVA
rs215795436 234 D>A No EVA
rs1132964291 276 M>K No EVA
rs3388470807 283 H>R No EVA
rs3388471072 284 S>Y No EVA
rs3388471639 285 G>R No EVA
rs3388470052 297 L>M No EVA
rs3388473195 299 E>K No EVA
rs3388471945 311 V>I No EVA
rs3388470674 337 D>N No EVA
rs3388471552 344 S>I No EVA
rs3390001890 352 T>I No EVA
rs3390001894 352 T>S No EVA
rs3388473050 354 S>P No EVA
rs3388470630 355 I>V No EVA
rs3388471623 360 R>M No EVA
rs217939647 364 V>I No EVA

No associated diseases with Q9D9H8

2 regional properties for Q9D9H8

Type Name Position InterPro Accession
domain RNA recognition motif domain 43 - 121 IPR000504
domain NCBP2, RNA recognition motif 45 - 122 IPR034148

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
respirasome The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
oxidative phosphorylation The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8N8R5 C2orf69 Mitochondrial protein C2orf69 Homo sapiens (Human) PR
10 20 30 40 50 60
MLGSRRLRSP ALVLLLLRPL LASGDSASRL QTRAMNPGGG ERGSPEDSHR LQRSTVPGSD
70 80 90 100 110 120
PQRSNELLLL TSREGDSPEQ RHHVLYFPGD VQNYHEIMTR HPENYQWENW SLENIATILA
130 140 150 160 170 180
RRFPNSYIWV IKCSRMHLHK FSCYDNFVKS NMFGAPEHTP DFGAFKHLYM LLVNAFNLTQ
190 200 210 220 230 240
NGMLFKNRSV WNKDCKASNC ESNPSTSNGG QKENERTCEH VDEPSMSFPP LSLDGASFTL
250 260 270 280 290 300
IGFSKGCVVL NQLLFELKEA KKDKNIDAFI KSIRTMYWLD GGHSGGSNTW VTYPEVLEEF
310 320 330 340 350 360
AQTGITVHTH VTPYQVHDPM RSWIGKEHKK FVQILRDLGM QVTSQIHFAK ETPSIENHFR
VHEVF