Q9D518

PR
Gene name
Fam227b
Protein name
Protein FAM227B
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:75823
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

51-129 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9D518

Entry ID Method Resolution Chain Position Source
AF-Q9D518-F1 Predicted AlphaFoldDB

18 variants for Q9D518

Variant ID(s) Position Change Description Diseaes Association Provenance
rs246083063 105 Y>C No EVA
rs3388581406 204 K>N No EVA
rs3388591757 288 F>L No EVA
rs3388583683 289 W>L No EVA
rs234617350 290 T>S No EVA
rs212359818 291 H>N No EVA
rs212359818 291 H>Y No EVA
rs3388586234 292 W>G No EVA
rs3388591825 305 S>N No EVA
rs3388586659 340 A>V No EVA
rs212407003 343 M>I No EVA
rs3388592133 346 L>R No EVA
rs3388591012 349 E>* No EVA
rs247699807 352 A>E No EVA
rs244340516 404 T>S No EVA
rs242210859 510 M>L No EVA
rs1134626321 511 Q>H No EVA
rs3388591764 524 E>* No EVA

No associated diseases with Q9D518

5 regional properties for Q9D518

Type Name Position InterPro Accession
domain Phenylalanyl-tRNA synthetase 210 - 483 IPR002319
domain Aminoacyl-tRNA synthetase, class II 229 - 491 IPR006195
domain PheRS DNA binding domain 2 134 - 165 IPR040586
domain PheRS, DNA binding domain 1 3 - 61 IPR040724
domain PheRS, DNA binding domain 3 75 - 132 IPR040725

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q96M60 FAM227B Protein FAM227B Homo sapiens (Human) PR
Q6AXP3 Fam227b Protein FAM227B Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MELPVPQKLP DPPRSFDEFL KSQNWDYWPR DVHFRDSDIW EDTLKKLEEA ISYTSIYSYL
70 80 90 100 110 120
WTNVPRLYDI VDSLESKLKE SSHLLQHHAS RLFESDKMIS KKRSYTNLER YKAFVKEHYR
130 140 150 160 170 180
PKKIALSDRM ETEKNIEGCT FLFNQNEVTQ LPRHLDAKQI YLYVLKTHNF EEKVFKVWKT
190 200 210 220 230 240
HVLSDCSIAL LHDSFWWWFL HKFKPDKRDE DFLFDRIAES YVTLFIKIPL RRKDAFFKMY
250 260 270 280 290 300
PDCLTQAVYT TFQESFPESC SLFNDKFKED LGNTIFLWLS GLKPETGFWT HWKLQDLCTT
310 320 330 340 350 360
TIHGSRRVPV KLRRSVIPSQ EHIPGIRDLK IEDILKNPRA YAMPKLMKES VASKAATKPS
370 380 390 400 410 420
HYRSLGPEFH KVLFDFGGQS PLILYYLKMH ELGGISVTHN PKGTKFTKIL REPSPAPTYC
430 440 450 460 470 480
DIIRDAKRKF ADNKKDFKRV KQRIKDDIKF LREQQELIDK ELDRIQAKAS KNLQEVKNEF
490 500 510 520 530
ENFLHKQRVE AKLKEEYGGS TSASESPQSM QSPQSSSSFP TISEDFNNVE EG