Q9D4V6
Gene name |
Tomm20l |
Protein name |
TOMM20-like protein 1 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:75266 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9D4V6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9D4V6-F1 | Predicted | AlphaFoldDB |
10 variants for Q9D4V6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs265345028 | 27 | V>A | No | EVA | |
| rs231717838 | 32 | R>K | No | EVA | |
| rs49277820 | 58 | A>T | No | EVA | |
| rs265932300 | 86 | I>T | No | EVA | |
| rs50179669 | 112 | M>R | No | EVA | |
| rs3389246314 | 115 | K>E | No | EVA | |
| rs3403412162 | 129 | K>N | No | EVA | |
| rs3389202426 | 133 | I>V | No | EVA | |
| rs1135380155 | 144 | T>M | No | EVA | |
| rs256670187 | 152 | D>N | No | EVA |
No associated diseases with Q9D4V6
No regional properties for Q9D4V6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9D4V6 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of mitochondrial outer membrane | The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial outer membrane translocase complex | A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| mitochondrion targeting sequence binding | Binding to a mitochondrion targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the mitochondrion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| protein import into mitochondrial matrix | The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together. |
| tRNA import into mitochondrion | The process in which a tRNA is transported from the cytosol into the mitochondrial matrix. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPSVRLGVGL | LAGLAAGGAV | VLLSYCVYLD | WRRHRDPAFR | RRLQDKRRAG | QPKAQAPARQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LWDPVKKEEL | QEYFFREVQM | GKLCLIRGER | GMGFEHLTNA | LLVCEQPKEL | LMFFKKTLPP |
| 130 | 140 | 150 | |||
| EVFQMLLDKI | PLICQQLEET | CRSTEHLKDD | PD |