Q9D338
Gene name |
Mrpl19 |
Protein name |
39S ribosomal protein L19, mitochondrial |
Names |
L19mt, MRP-L19 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:56284 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9D338
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9D338-F1 | Predicted | AlphaFoldDB |
13 variants for Q9D338
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3388820181 | 10 | R>G | No | EVA | |
| rs237594426 | 37 | C>R | No | EVA | |
| rs1133924838 | 39 | G>D | No | EVA | |
| rs3413011258 | 60 | P>S | No | EVA | |
| rs248254207 | 72 | E>Q | No | EVA | |
| rs3388816639 | 98 | D>V | No | EVA | |
| rs3396902866 | 134 | L>A | No | EVA | |
| rs263359183 | 213 | Q>K | No | EVA | |
| rs584187168 | 234 | E>Q | No | EVA | |
| rs3388839367 | 264 | W>* | No | EVA | |
| rs3388834835 | 282 | L>F | No | EVA | |
| rs3388832331 | 287 | E>K | No | EVA | |
| rs3388831957 | 290 | K>N | No | EVA |
No associated diseases with Q9D338
No regional properties for Q9D338
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9D338 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
| mitochondrial large ribosomal subunit | The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site). |
| mitochondrial ribosome | A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial translation | The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAASMAESCR | ASLYLARSVR | MARPRLAAFA | SDACRVCTGP | SRFQSTGPSE | PGGFKPPPKP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VIVDRRRVPE | DERRFLSPEF | IPPRGRTNPL | KFKIERKDML | DRRKVLPIPE | FYVGSILRVT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TADPYASGKT | SQFLGICIKR | SGNGLGATFT | LRNTIEGQGV | EICFELYNPR | IQEIQVVKLE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KRLDDNLLYL | RDALPEYSTF | DVNMKPVPQE | ACQEVPVNKL | KVKMKPKPWS | KRWERPNFNI |
| 250 | 260 | 270 | 280 | 290 | |
| KGIRFDLALT | EEQMKEAQKW | NKPWIEFDMM | REYDTSKIEA | ALWEEIEASK | KS |