Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9CYI0

Entry ID Method Resolution Chain Position Source
AF-Q9CYI0-F1 Predicted AlphaFoldDB

15 variants for Q9CYI0

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389121252 10 D>N No EVA
rs242120318 28 R>Q No EVA
rs3389173726 29 R>T No EVA
rs259375346 138 I>V No EVA
rs247751246 163 E>D No EVA
rs243786869 179 N>D No EVA
rs3389194302 190 D>E No EVA
rs3389150751 216 K>T No EVA
rs3389185005 248 S>N No EVA
rs3389121261 260 T>S No EVA
rs3389186773 284 Q>P No EVA
rs240576968 339 Q>H No EVA
rs3389194300 349 K>R No EVA
rs3389189625 373 E>K No EVA
rs262787754 382 A>T No EVA

No associated diseases with Q9CYI0

No regional properties for Q9CYI0

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9CYI0

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasmic vesicle A vesicle found in the cytoplasm of a cell.
trans-Golgi network The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
vesicle tethering to Golgi The initial, indirect interaction between a transport vesicle membrane and the membrane of the Golgi. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9HAS0 C17orf75 Protein Njmu-R1 Homo sapiens (Human) PR
10 20 30 40 50 60
MLPSLQESLD GDEKELESSE EGGSAEERRL EPPPSSHYCL YSFRGSRLTQ NRGDSDDGRS
70 80 90 100 110 120
GGINAETPSG DDFSLSLVDT NLPSEVEPEL RSFIAKRLSK GAVFEGLGNV ASVELRIPGY
130 140 150 160 170 180
RVGCYYCLFQ QEKLLPEIAA MESEHNPSEY VVCFLGGSEK GLELFRLELD KYIQGLKNNM
190 200 210 220 230 240
NCEERSLGND VKSYLNSWYE DVVCPIQRVV LLFQEKLTFL LHAALSYTPV EFKESDEKTK
250 260 270 280 290 300
RDINRFLSVA SLQGLIHEGT MTSLCMAMTE EQHKSVIIDC SGPQPQFHNA GSNRFCEDWM
310 320 330 340 350 360
QAFLHGAEAG NPFLFRQVLE NFKLKAIQDT NNLKRFIRQA EMNHYALFKC YMFLKNCGSG
370 380 390
DILLKIVKVE HEEMPEAKSV VAVLEEFMRE ALV