Q9CPA9

PR
Gene name
ftsW
Protein name
Probable peptidoglycan glycosyltransferase FtsW
Names
PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase
Species
Pasteurella multocida (strain Pm70)
KEGG Pathway
pmu:PM0141
EC number
2.4.1.129: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

352-396 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9CPA9

Entry ID Method Resolution Chain Position Source
AF-Q9CPA9-F1 Predicted AlphaFoldDB

No variants for Q9CPA9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9CPA9

No associated diseases with Q9CPA9

9 regional properties for Q9CPA9

Type Name Position InterPro Accession
domain Elongation factor EFG, domain V-like 604 - 691 IPR000640
domain Translational (tr)-type GTP-binding domain 8 - 288 IPR000795
domain Translation elongation factor EFTu-like, domain 2 328 - 395 IPR004161
domain Small GTP-binding protein domain 10 - 185 IPR005225
domain Translation elongation factor EFG/EF2, domain IV 483 - 602 IPR005517
domain Elongation factor G, domain III 409 - 484 IPR009022
conserved_site Tr-type G domain, conserved site 51 - 66 IPR031157
domain EFG, domain V 607 - 684 IPR035649
domain Elongation Factor G, domain II 408 - 481 IPR041095

Functions

Description
EC Number 2.4.1.129 Hexosyltransferases
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
  • Localizes to the division septum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cell division site The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
peptidoglycan glycosyltransferase activity Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate.

4 GO annotations of biological process

Name Definition
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
FtsZ-dependent cytokinesis A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells.
peptidoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
regulation of cell shape Any process that modulates the surface configuration of a cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPFLDKVKQQ YEDWTRITPS NLLYDRALLL LFFVLLLIGL LAVSSASIPV GTRLFKDPFY
70 80 90 100 110 120
FAKRDAIYVF LSCVTCYLCV QVPMEKWEQW HVRLFAFAIF LLILVLIPGI GLSVNGARRW
130 140 150 160 170 180
IPMVLFNFQP AEFAKLALTC FLASYFTRKY DEVRSRKLSA FKPFALMGLM GLFLLSQPDL
190 200 210 220 230 240
GSTVVLFVIT FGLLFIVGAN FWQFVGLMAF GGLLFVWLVL SSAYRLKRFT GFLDPFKDPY
250 260 270 280 290 300
GTGFQLSNSL MAFGRGEWVG EGLGNSIQKL EYLPEAHTDF VMAVVGEEFG FLGILVIVIL
310 320 330 340 350 360
LGLLIFRAMK IGRESLLLEQ RFKGFFAFGI SFWIFFQGFV NLGMSLGLLP TKGLTFPLIS
370 380 390
YGGSSLIIMS MTIGLLLRID HENRLMRIGQ ARLRDD