Q9CH00

PR
Gene name
rnr1 (vacB1, LL0942, L0323)
Protein name
Ribonuclease R 1
Names
RNase R 1, VacB protein homolog 1
Species
Lactococcus lactis subsp lactis (strain IL1403) (Streptococcus lactis)
KEGG Pathway
lla:L0323
EC number
3.1.13.1: Exoribonucleases producing 5'-phosphomonoesters
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

695-817 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9CH00

Entry ID Method Resolution Chain Position Source
AF-Q9CH00-F1 Predicted AlphaFoldDB

No variants for Q9CH00

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9CH00

No associated diseases with Q9CH00

6 regional properties for Q9CH00

Type Name Position InterPro Accession
domain Ribonuclease II/R 259 - 588 IPR001900
domain S1 domain 636 - 717 IPR003029
domain Ribonuclease B, N-terminal OB domain 74 - 128 IPR013223
conserved_site Ribonuclease II/R, conserved site 555 - 579 IPR022966
domain RNA-binding domain, S1 635 - 717 IPR022967
domain RNase II/RNase R, cold shock domain 162 - 237 IPR040476

Functions

Description
EC Number 3.1.13.1 Exoribonucleases producing 5'-phosphomonoesters
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
exoribonuclease II activity Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction.
RNA binding Binding to an RNA molecule or a portion thereof.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSIREVIMDY LENSSKKALS VEELSVALHM NKAKDYKVFV KTLASLEAEH LLNFTAKGKV
70 80 90 100 110 120
ELAEKEEAKV VISGIFRANA AGFGFVSIDA EEPDVFVARG QTAFALDGDE VFIEIDKNAN
130 140 150 160 170 180
ALKGTSAEGH VVEIIRHDVH QVVGTFVALN DDEKEQTGLI GFVKSRNKKI PYRVYLENEG
190 200 210 220 230 240
LIPENKAIVR VEITHYPDKE FPQTMQGLVT EIIGQADDQG IDVLEVLASM DIVSEFPKEV
250 260 270 280 290 300
LDQAEAVPEE VPENEIVGRV DYRNEITFTI DGADAKDLDD AVHAKRLENG NYELGVHIAD
310 320 330 340 350 360
VSHYVTENSP LDKEAYERGT SVYVTDRVVP MLPERLSNGI CSLNPRINRL TQSCVMEISP
370 380 390 400 410 420
EGRVINYQIS QSIIKTTERM TYDAVNQMIA GDEAALENYA KIADSVKIMV ELHHILEAMR
430 440 450 460 470 480
KRRGAIDFDT VEAKIIVNEK GLPIEIRKRT RGIAERMIES FMLEANETVA THFEAHGLPF
490 500 510 520 530 540
IYRIHEQPKA DRLQRFIDFA ATFGMQIEGT SNGIDQKVLQ AFMKKIKGQP GEMVLSTMLL
550 560 570 580 590 600
RSMQQARYSE NNEGHFGLAA ENYTHFTSPI RRYPDLLVHR LIREIGEGKT PANILQKWED
610 620 630 640 650 660
KIPEIAEHSS HRERRAVDAE REVEKMKKAE FMEEHVGEEY EGIIASVTRF GMFIELENTI
670 680 690 700 710 720
EGLVHISTLK GDYFNYQERM LALIGERSGL TFKIGQPIKI KVVKADRMTG EIDFEYLPSE
730 740 750 760 770 780
LDLIDKAAKA KKKPDHKGRK KSNQSLKVKS VAPKSTDKSA NKSKNGRRAD EKFEFDKKKK
790 800 810
KSAKKPFYSK AAKGKFTDKK DNGKKFTDGR KKPHKRG