Q9C8Z9

PR
Gene name
BHLH148
Protein name
Transcription factor bHLH148
Names
ATBS1 interacting factor 2, Basic helix-loop-helix protein 148, AtbHLH148, bHLH 148, Protein RSA1 INTERACTING TRANSCRIPTION FACTOR 1, AtRITF1, Transcription factor EN 143, bHLH transcription factor bHLH148
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G06590
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-180 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9C8Z9

Entry ID Method Resolution Chain Position Source
AF-Q9C8Z9-F1 Predicted AlphaFoldDB

15 variants for Q9C8Z9

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_3_2055216_A_G 33 S>P No 1000Genomes
ENSVATH13879733 50 S>P No 1000Genomes
tmp_3_2055140_G_A 58 S>L No 1000Genomes
ENSVATH02119296 77 S>P No 1000Genomes
ENSVATH13879731 82 A>V No 1000Genomes
ENSVATH05785425 123 Q>L No 1000Genomes
ENSVATH00309750 130 M>V No 1000Genomes
ENSVATH10529449 132 I>V No 1000Genomes
ENSVATH05785424 164 V>I No 1000Genomes
ENSVATH05785423 167 K>R No 1000Genomes
tmp_3_2054805_C_T 170 V>I No 1000Genomes
ENSVATH10529447 176 P>T No 1000Genomes
tmp_3_2054769_A_T 182 S>T No 1000Genomes
ENSVATH10529384 190 A>T No 1000Genomes
tmp_3_2054701_C_A 204 M>I No 1000Genomes

No associated diseases with Q9C8Z9

2 regional properties for Q9C8Z9

Type Name Position InterPro Accession
domain SIS domain 7 - 217 IPR001347
domain RpiR-like, SIS domain 25 - 185 IPR035472

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
protein dimerization activity The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

4 GO annotations of biological process

Name Definition
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
response to hydrogen peroxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
response to salt stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASLISDIEP PTSTTSDLVR RKKRSSASSA ASSRSSASSV SGEIHARWRS EKQQRIYSAK
70 80 90 100 110 120
LFQALQQVRL NSSASTSSSP TAQKRGKAVR EAADRALAVS ARGRTLWSRA ILANRIKLKF
130 140 150 160 170 180
RKQRRPRATM AIPAMTTVVS SSSNRSRKRR VSVLRLNKKS IPDVNRKVRV LGRLVPGCGK
190 200 210 220
QSVPVILEEA TDYIQALEMQ VRAMNSLVQL LSSYGSAPPP I