Q9C2L8
Gene name |
gtp-14 (17E5.300, NCU03711) |
Protein name |
Ypt/Rab-type GTPase Rab7 |
Names |
Guanine triphosphate binding protein 14 |
Species |
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) |
KEGG Pathway |
ncr:NCU03711 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9C2L8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9C2L8-F1 | Predicted | AlphaFoldDB |
No variants for Q9C2L8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9C2L8 | |||||
No associated diseases with Q9C2L8
1 regional properties for Q9C2L8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 10 - 171 | IPR005225 |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| fungal-type vacuole membrane | The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae. |
| late endosome | A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center. |
| phagocytic vesicle | A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| vacuole | A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| regulation of vacuole fusion, non-autophagic | Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSRKKVLLK | VIILGDSGVG | KTSLMNQYVN | KKFSASYKAT | IGADFLTREV | LVDDRQVTMQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LWDTAGQERF | QSLGVAFYRG | ADCCVLVYDV | NNSKSFDALD | SWRDEFLIQA | SPRDPDNFPF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VVLGNKIDME | ESKRVISTKR | AMTFCQSKGN | IPYFETSAKE | AINVEQAFEV | IARNALMQEE |
| 190 | 200 | ||||
| SEEFSGDFQD | PINIHIENDR | DGCAC |